HRP20191293T1 - Anti-transglutaminaza 2 antitijela - Google Patents

Anti-transglutaminaza 2 antitijela Download PDF

Info

Publication number
HRP20191293T1
HRP20191293T1 HRP20191293TT HRP20191293T HRP20191293T1 HR P20191293 T1 HRP20191293 T1 HR P20191293T1 HR P20191293T T HRP20191293T T HR P20191293TT HR P20191293 T HRP20191293 T HR P20191293T HR P20191293 T1 HRP20191293 T1 HR P20191293T1
Authority
HR
Croatia
Prior art keywords
antibody
antigen
sequence
chain variable
variable region
Prior art date
Application number
HRP20191293TT
Other languages
English (en)
Croatian (hr)
Inventor
Tim Johnson
Phil WATSON
David Matthews
Alex Brown
Original Assignee
Lifearc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46546551&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20191293(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lifearc filed Critical Lifearc
Publication of HRP20191293T1 publication Critical patent/HRP20191293T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1075Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against an enzyme
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Addiction (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
HRP20191293TT 2012-05-24 2013-05-24 Anti-transglutaminaza 2 antitijela HRP20191293T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1209096.5A GB201209096D0 (en) 2012-05-24 2012-05-24 Compounds
EP13730049.7A EP2855530B1 (en) 2012-05-24 2013-05-24 Anti-transglutaminase 2 antibodies
PCT/GB2013/051373 WO2013175229A1 (en) 2012-05-24 2013-05-24 Anti -transglutaminase 2 antibodies

Publications (1)

Publication Number Publication Date
HRP20191293T1 true HRP20191293T1 (hr) 2019-10-18

Family

ID=46546551

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20191293TT HRP20191293T1 (hr) 2012-05-24 2013-05-24 Anti-transglutaminaza 2 antitijela
HRP20202059TT HRP20202059T1 (hr) 2012-05-24 2020-12-23 Anti-transglutaminaza 2 antitijela

Family Applications After (1)

Application Number Title Priority Date Filing Date
HRP20202059TT HRP20202059T1 (hr) 2012-05-24 2020-12-23 Anti-transglutaminaza 2 antitijela

Country Status (39)

Country Link
US (3) US10005846B2 (OSRAM)
EP (2) EP3521315B1 (OSRAM)
JP (2) JP6411998B2 (OSRAM)
KR (1) KR102091223B1 (OSRAM)
CN (1) CN104321346B (OSRAM)
AU (1) AU2013265025B2 (OSRAM)
BR (1) BR112014029089B1 (OSRAM)
CA (1) CA2874488C (OSRAM)
CL (1) CL2014003125A1 (OSRAM)
CO (1) CO7151528A2 (OSRAM)
CY (2) CY1121932T1 (OSRAM)
DK (2) DK3521315T3 (OSRAM)
EA (1) EA036810B1 (OSRAM)
EC (1) ECSP14030942A (OSRAM)
ES (2) ES2728856T3 (OSRAM)
GB (1) GB201209096D0 (OSRAM)
HR (2) HRP20191293T1 (OSRAM)
HU (2) HUE045539T2 (OSRAM)
IL (1) IL235369B (OSRAM)
IN (1) IN2014MN02231A (OSRAM)
LT (2) LT3521315T (OSRAM)
MA (1) MA37670B1 (OSRAM)
ME (1) ME03393B (OSRAM)
MX (1) MX367517B (OSRAM)
MY (1) MY185966A (OSRAM)
NZ (1) NZ701424A (OSRAM)
PE (1) PE20150346A1 (OSRAM)
PH (1) PH12014502582A1 (OSRAM)
PL (2) PL3521315T3 (OSRAM)
PT (2) PT2855530T (OSRAM)
RS (2) RS61286B1 (OSRAM)
SG (1) SG11201407053YA (OSRAM)
SI (2) SI3521315T1 (OSRAM)
SM (2) SMT201900407T1 (OSRAM)
TN (1) TN2014000458A1 (OSRAM)
TR (1) TR201906781T4 (OSRAM)
UA (1) UA117657C2 (OSRAM)
WO (1) WO2013175229A1 (OSRAM)
ZA (1) ZA201408213B (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110055235A (zh) * 2019-05-14 2019-07-26 深圳市亚辉龙生物科技股份有限公司 用于转谷氨酰胺酶抗体检测的抗原及其制备方法、试剂盒及检测方法
FR3117599B1 (fr) * 2020-12-16 2024-11-29 Oreal Méthode de pronostic et/ou de diagnostic d’un état pelliculaire du cuir chevelu
GB202115127D0 (en) 2021-10-21 2021-12-08 Ucb Biopharma Sprl Formulations
GB202115121D0 (en) 2021-10-21 2021-12-08 Ucb Biopharma Sprl Formulations
GB202116665D0 (en) 2021-11-18 2022-01-05 UCB Biopharma SRL Method for the treatment of a scleroderma disease
JP2024540753A (ja) 2021-11-18 2024-11-01 ユーシービー ビオファルマ ソシエタ ア レスポンサビリタ リミタータ 進行性慢性間質性肺疾患の治療方法
GB202118010D0 (en) 2021-12-13 2022-01-26 UCB Biopharma SRL Method for detecting and/or quantifying crosslinks formed by transglutaminases
CN116515786B (zh) * 2023-04-26 2024-05-28 广东医科大学 一种人tgm3乙酰化多肽、抗原、抗体及其制备方法和应用
WO2025153465A1 (en) 2024-01-15 2025-07-24 UCB Biopharma SRL Method for the treatment of fibrotic-related disorder associated to ibd

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4912120A (en) 1986-03-14 1990-03-27 Syntex (U.S.A.) Inc. 3,5-substituted 4,5-dihydroisoxazoles as transglutaminase inhibitors
WO1992012238A1 (en) 1991-01-04 1992-07-23 The Board Of Regents, University Of Texas System Cloning and expression of tissue transglutaminases
AU6620596A (en) 1996-07-25 1998-02-20 Victoria University Of Manchester, The Use of transglutaminase modulators to promote wound healing
GB0103024D0 (en) * 2001-02-07 2001-03-21 Rsr Ltd Assay for Autoantibodies to tissue transglutaminase
US20060211624A1 (en) 2003-02-02 2006-09-21 Goverment of the US, as Represented by Methods and compositions for the treatment of parkinson's disease and other alpha-synucleinopathies
GB0314262D0 (en) 2003-06-19 2003-07-23 Univ Nottingham Trent Novel compounds and methods of using the same
WO2006100679A2 (en) * 2005-03-22 2006-09-28 Quark Pharmaceuticals, Inc. Recombinant antibodies against human type ii transglutaminase and uses thereof
US8299040B2 (en) 2006-10-18 2012-10-30 Board Of Regents, The University Of Texas System Methods for treating cancer targeting transglutaminase
US8614296B2 (en) * 2008-04-24 2013-12-24 Gene Techno Science Co., Ltd. Humanized antibodies specific for amino acid sequence RGD of an extracellular matrix protein and the uses thereof
KR20110139736A (ko) 2009-03-19 2011-12-29 퀸스랜드 유니버시티 오브 테크놀로지 성장 인자 시그널링을 위한 표적 및 치료 방법
HU0900195D0 (en) * 2009-04-01 2009-06-29 Debreceni Egyetem Diagnosis and treatment of gluten-induced autoimmune diseases
HU0900199D0 (en) * 2009-04-01 2009-06-29 Debreceni Egyetem Diagnosis of gluten-induced autoimmune diseases
WO2011151395A2 (en) 2010-06-02 2011-12-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Transglutaminase 2 inhibitors for use in the prevention or treatment of rapidly progressive glomerulonephritis
GB2490655A (en) 2011-04-28 2012-11-14 Univ Aston Modulators of tissue transglutaminase

Also Published As

Publication number Publication date
ZA201408213B (en) 2020-02-26
UA117657C2 (uk) 2018-09-10
PH12014502582B1 (en) 2015-01-21
EP2855530A1 (en) 2015-04-08
HUE045539T2 (hu) 2019-12-30
MX2014014264A (es) 2015-05-15
US10961319B2 (en) 2021-03-30
KR20150013340A (ko) 2015-02-04
CL2014003125A1 (es) 2015-08-21
SI3521315T1 (sl) 2020-12-31
EP3521315A1 (en) 2019-08-07
CA2874488A1 (en) 2013-11-28
CY1123926T1 (el) 2022-05-27
PL3521315T3 (pl) 2021-08-23
SMT202100014T1 (it) 2021-03-15
SG11201407053YA (en) 2014-12-30
EP3521315B1 (en) 2020-10-14
DK3521315T3 (da) 2020-11-09
PE20150346A1 (es) 2015-03-05
AU2013265025B2 (en) 2018-04-26
CO7151528A2 (es) 2014-12-29
NZ701424A (en) 2016-08-26
HK1203974A1 (en) 2015-11-06
IL235369B (en) 2019-05-30
LT2855530T (lt) 2019-07-25
US10005846B2 (en) 2018-06-26
RS59135B1 (sr) 2019-09-30
TN2014000458A1 (en) 2016-03-30
MY185966A (en) 2021-06-14
PH12014502582A1 (en) 2015-01-21
ECSP14030942A (es) 2015-09-30
AU2013265025A1 (en) 2014-12-04
US20180355060A1 (en) 2018-12-13
RS61286B1 (sr) 2021-02-26
WO2013175229A1 (en) 2013-11-28
CN104321346B (zh) 2018-12-07
MA37670B1 (fr) 2019-12-31
SI2855530T1 (sl) 2019-08-30
KR102091223B1 (ko) 2020-03-20
CY1121932T1 (el) 2020-10-14
CA2874488C (en) 2021-09-07
LT3521315T (lt) 2020-12-28
JP2015519897A (ja) 2015-07-16
TR201906781T4 (tr) 2019-05-21
PL2855530T3 (pl) 2019-10-31
HRP20202059T1 (hr) 2021-02-19
EA201492162A1 (ru) 2015-03-31
MA37670A1 (fr) 2016-05-31
BR112014029089A2 (pt) 2019-06-25
US20150218289A1 (en) 2015-08-06
DK2855530T3 (da) 2019-06-24
PT2855530T (pt) 2019-07-08
BR112014029089B1 (pt) 2023-04-25
IN2014MN02231A (OSRAM) 2015-07-24
IL235369A0 (en) 2014-12-31
JP6411998B2 (ja) 2018-10-24
CN104321346A (zh) 2015-01-28
US11718686B2 (en) 2023-08-08
ES2728856T3 (es) 2019-10-29
JP2018166510A (ja) 2018-11-01
SMT201900407T1 (it) 2019-09-09
EA036810B1 (ru) 2020-12-23
EP2855530B1 (en) 2019-05-01
US20210101999A1 (en) 2021-04-08
PT3521315T (pt) 2020-10-29
GB201209096D0 (en) 2012-07-04
HUE052490T2 (hu) 2021-04-28
ES2835383T3 (es) 2021-06-22
ME03393B (me) 2020-01-20
MX367517B (es) 2019-08-26

Similar Documents

Publication Publication Date Title
HRP20191293T1 (hr) Anti-transglutaminaza 2 antitijela
US20200377578A1 (en) Neutralising antibodies to the major exotoxins tcda and tcdb of clostridium difficile
CA2994425C (en) Pd-l1 ("programmed death-ligand 1") antibodies
RU2495050C2 (ru) Связующий элемент для рецептора gm-csf
HRP20201399T1 (hr) Novi modulatori i postupci njihove uporabe
RU2018119165A (ru) Антитело против лиганда 1 запрограммированной гибели клеток (pd-l1), его антигенсвязывающий фрагмент и их медицинское применение
IL278574B2 (en) Glycan-interacting compounds and methods of use
NZ625403A (en) Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
JP2013543498A5 (OSRAM)
JP2017500028A5 (OSRAM)
JP2014511179A5 (OSRAM)
HRP20201595T1 (hr) Anti-pd-l1 protutijela i njihova uporaba
NZ601293A (en) Compositions and methods for the diagnosis and treatment of tumor
RU2014139552A (ru) Человеческие антитела к токсинам clostridium difficile
JP2015519897A5 (OSRAM)
EP4403226A3 (en) Anti-psma antibodies, uses thereof and conjugates thereof
JP2020502198A5 (OSRAM)
RU2017144629A (ru) Тромбин-связывающие молекулы антител и их применение
RU2018121413A (ru) Антитело ANTI-PCSK9 и его применение
CN120475994A (zh) 抗bdca2抗体-药物偶联物及其用途
NZ761838A (en) Cd38 antibody
NZ761020A (en) Cd38 modulating antibody
NZ760342A (en) Cd38 modulating antibody
NZ761020B2 (en) Cd38 modulating antibody
NZ760342B2 (en) Cd38 modulating antibody