HRP20190449T1 - Hidrobromidna sol n-(4-klor-2-hidroksi-3-((3s)-3-piperidinilsulfonil)fenil)-n’-(3-fluor-2-metilfenil)uree - Google Patents

Hidrobromidna sol n-(4-klor-2-hidroksi-3-((3s)-3-piperidinilsulfonil)fenil)-n’-(3-fluor-2-metilfenil)uree

Info

Publication number
HRP20190449T1
HRP20190449T1 HRP20190449TT HRP20190449T HRP20190449T1 HR P20190449 T1 HRP20190449 T1 HR P20190449T1 HR P20190449T T HRP20190449T T HR P20190449TT HR P20190449 T HRP20190449 T HR P20190449T HR P20190449 T1 HRP20190449 T1 HR P20190449T1
Authority
HR
Croatia
Prior art keywords
piperidinylsulphonyl
uree
fluor
hydrobromide
methylphenyl
Prior art date
Application number
HRP20190449TT
Other languages
English (en)
Croatian (hr)
Inventor
Francis Dominic Sanderson
Sarah Mary VALLANCE
Original Assignee
Glaxosmithkline Intellectual Property (No. 2) Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Intellectual Property (No. 2) Limited filed Critical Glaxosmithkline Intellectual Property (No. 2) Limited
Publication of HRP20190449T1 publication Critical patent/HRP20190449T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4462—Non condensed piperidines, e.g. piperocaine only substituted in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/452—Piperidinium derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
HRP20190449TT 2013-11-13 2014-11-11 Hidrobromidna sol n-(4-klor-2-hidroksi-3-((3s)-3-piperidinilsulfonil)fenil)-n’-(3-fluor-2-metilfenil)uree HRP20190449T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1320021.7A GB201320021D0 (en) 2013-11-13 2013-11-13 Novel Compounds
EP14799988.2A EP3068763B1 (en) 2013-11-13 2014-11-11 Hydrobromide salt of n-(4-chloro-2-hydroxy-3-((3s)-3-piperidinylsulfonyl)phenyl)-n'-(3-fluoro-2-methylphenyl)urea
PCT/EP2014/074222 WO2015071235A1 (en) 2013-11-13 2014-11-11 Hydrobromide salt ofn-(4-chloro-2-hydroxy-3-((3s)-3-piperidinylsulfonyl)phenyl-n'-(3-fluoro-2-methylphenyl)urea

Publications (1)

Publication Number Publication Date
HRP20190449T1 true HRP20190449T1 (hr) 2019-04-19

Family

ID=49818555

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20190449TT HRP20190449T1 (hr) 2013-11-13 2014-11-11 Hidrobromidna sol n-(4-klor-2-hidroksi-3-((3s)-3-piperidinilsulfonil)fenil)-n’-(3-fluor-2-metilfenil)uree

Country Status (24)

Country Link
US (3) US9809540B2 (https=)
EP (1) EP3068763B1 (https=)
JP (1) JP6401265B2 (https=)
KR (1) KR20160083950A (https=)
CN (1) CN105683162A (https=)
AU (1) AU2014350334B2 (https=)
BR (1) BR112016010409A8 (https=)
CA (1) CA2929907A1 (https=)
CY (1) CY1121581T1 (https=)
DK (1) DK3068763T3 (https=)
ES (1) ES2714721T3 (https=)
GB (1) GB201320021D0 (https=)
HR (1) HRP20190449T1 (https=)
HU (1) HUE041873T2 (https=)
LT (1) LT3068763T (https=)
ME (1) ME03328B (https=)
PL (1) PL3068763T3 (https=)
PT (1) PT3068763T (https=)
RS (1) RS58382B1 (https=)
RU (1) RU2685408C1 (https=)
SI (1) SI3068763T1 (https=)
SM (1) SMT201900156T1 (https=)
TR (1) TR201902981T4 (https=)
WO (1) WO2015071235A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170100385A1 (en) * 2014-05-12 2017-04-13 Glaxosmithkline Intellectual Property (No. 2) Limited Pharmaceutical compositions comprising danirixin for treating infectious diseases
BR112018011138A2 (pt) * 2015-11-30 2018-11-21 Glaxosmithkline Intellectual Property (No. formulações para administração intravenosa
WO2018073248A1 (en) 2016-10-17 2018-04-26 Icm (Institut Du Cerveau Et De La Moelle Épinière) Prognosis of demyelinating diseases patients and treatment thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2009992T3 (pl) * 2006-04-21 2012-11-30 Glaxosmithkline Llc Antagoniści receptora IL-8

Also Published As

Publication number Publication date
TR201902981T4 (tr) 2019-03-21
US20180079722A1 (en) 2018-03-22
RU2685408C1 (ru) 2019-04-18
RS58382B1 (sr) 2019-04-30
RU2016116955A (ru) 2017-12-19
EP3068763A1 (en) 2016-09-21
LT3068763T (lt) 2019-03-12
AU2014350334B2 (en) 2017-08-10
PT3068763T (pt) 2019-03-20
CY1121581T1 (el) 2020-05-29
JP2016537344A (ja) 2016-12-01
US20190112269A1 (en) 2019-04-18
GB201320021D0 (en) 2013-12-25
CN105683162A (zh) 2016-06-15
US9809540B2 (en) 2017-11-07
HUE041873T2 (hu) 2019-05-28
BR112016010409A8 (pt) 2020-04-22
EP3068763B1 (en) 2018-12-19
KR20160083950A (ko) 2016-07-12
SI3068763T1 (sl) 2019-04-30
ME03328B (me) 2019-10-20
US10604485B2 (en) 2020-03-31
CA2929907A1 (en) 2015-05-21
DK3068763T3 (en) 2019-03-18
ES2714721T3 (es) 2019-05-29
PL3068763T3 (pl) 2019-05-31
WO2015071235A1 (en) 2015-05-21
SMT201900156T1 (it) 2019-05-10
JP6401265B2 (ja) 2018-10-10
AU2014350334A1 (en) 2016-06-02
US20160264525A1 (en) 2016-09-15

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