ME03328B - Hidrobromidna so n-(4-hloro-2-hidroksi-3-((3s)-3-piperidinilsulfonil)fenil)-n’-(3-fluoro-2-metilfenil)uree - Google Patents
Hidrobromidna so n-(4-hloro-2-hidroksi-3-((3s)-3-piperidinilsulfonil)fenil)-n’-(3-fluoro-2-metilfenil)ureeInfo
- Publication number
- ME03328B ME03328B MEP-2019-47A MEP201947A ME03328B ME 03328 B ME03328 B ME 03328B ME P201947 A MEP201947 A ME P201947A ME 03328 B ME03328 B ME 03328B
- Authority
- ME
- Montenegro
- Prior art keywords
- piperidinylsulfonyl
- methylphenyl
- fluoro
- chloro
- urea
- Prior art date
Links
- NGYNBSHYFOFVLS-LBPRGKRZSA-N 1-[4-chloro-2-hydroxy-3-[(3s)-piperidin-3-yl]sulfonylphenyl]-3-(3-fluoro-2-methylphenyl)urea Chemical compound CC1=C(F)C=CC=C1NC(=O)NC1=CC=C(Cl)C(S(=O)(=O)[C@@H]2CNCCC2)=C1O NGYNBSHYFOFVLS-LBPRGKRZSA-N 0.000 title 1
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical class Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4462—Non condensed piperidines, e.g. piperocaine only substituted in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/452—Piperidinium derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1320021.7A GB201320021D0 (en) | 2013-11-13 | 2013-11-13 | Novel Compounds |
| EP14799988.2A EP3068763B1 (en) | 2013-11-13 | 2014-11-11 | Hydrobromide salt of n-(4-chloro-2-hydroxy-3-((3s)-3-piperidinylsulfonyl)phenyl)-n'-(3-fluoro-2-methylphenyl)urea |
| PCT/EP2014/074222 WO2015071235A1 (en) | 2013-11-13 | 2014-11-11 | Hydrobromide salt ofn-(4-chloro-2-hydroxy-3-((3s)-3-piperidinylsulfonyl)phenyl-n'-(3-fluoro-2-methylphenyl)urea |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ME03328B true ME03328B (me) | 2019-10-20 |
Family
ID=49818555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MEP-2019-47A ME03328B (me) | 2013-11-13 | 2014-11-11 | Hidrobromidna so n-(4-hloro-2-hidroksi-3-((3s)-3-piperidinilsulfonil)fenil)-n’-(3-fluoro-2-metilfenil)uree |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US9809540B2 (me) |
| EP (1) | EP3068763B1 (me) |
| JP (1) | JP6401265B2 (me) |
| KR (1) | KR20160083950A (me) |
| CN (1) | CN105683162A (me) |
| AU (1) | AU2014350334B2 (me) |
| BR (1) | BR112016010409A8 (me) |
| CA (1) | CA2929907A1 (me) |
| CY (1) | CY1121581T1 (me) |
| DK (1) | DK3068763T3 (me) |
| ES (1) | ES2714721T3 (me) |
| GB (1) | GB201320021D0 (me) |
| HR (1) | HRP20190449T1 (me) |
| HU (1) | HUE041873T2 (me) |
| LT (1) | LT3068763T (me) |
| ME (1) | ME03328B (me) |
| PL (1) | PL3068763T3 (me) |
| PT (1) | PT3068763T (me) |
| RS (1) | RS58382B1 (me) |
| RU (1) | RU2685408C1 (me) |
| SI (1) | SI3068763T1 (me) |
| SM (1) | SMT201900156T1 (me) |
| TR (1) | TR201902981T4 (me) |
| WO (1) | WO2015071235A1 (me) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015173701A2 (en) * | 2014-05-12 | 2015-11-19 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pharmaceutical compositions for treating infectious diseases |
| CA3006865A1 (en) * | 2015-11-30 | 2017-06-08 | Glaxosmithkline Intellectual Property (No.2) Limited | Formulations for intravenous injection of danirixin |
| WO2018073248A1 (en) | 2016-10-17 | 2018-04-26 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Prognosis of demyelinating diseases patients and treatment thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2008013600A (es) | 2006-04-21 | 2008-10-31 | Smithkline Beechman Corp | Antagonistas del receptor de interleuquina-8. |
-
2013
- 2013-11-13 GB GBGB1320021.7A patent/GB201320021D0/en not_active Ceased
-
2014
- 2014-11-11 BR BR112016010409A patent/BR112016010409A8/pt not_active IP Right Cessation
- 2014-11-11 ME MEP-2019-47A patent/ME03328B/me unknown
- 2014-11-11 US US15/034,583 patent/US9809540B2/en not_active Expired - Fee Related
- 2014-11-11 PT PT14799988T patent/PT3068763T/pt unknown
- 2014-11-11 ES ES14799988T patent/ES2714721T3/es active Active
- 2014-11-11 TR TR2019/02981T patent/TR201902981T4/tr unknown
- 2014-11-11 DK DK14799988.2T patent/DK3068763T3/en active
- 2014-11-11 WO PCT/EP2014/074222 patent/WO2015071235A1/en not_active Ceased
- 2014-11-11 PL PL14799988T patent/PL3068763T3/pl unknown
- 2014-11-11 HR HRP20190449TT patent/HRP20190449T1/hr unknown
- 2014-11-11 JP JP2016529894A patent/JP6401265B2/ja not_active Expired - Fee Related
- 2014-11-11 RS RS20190230A patent/RS58382B1/sr unknown
- 2014-11-11 SI SI201431125T patent/SI3068763T1/sl unknown
- 2014-11-11 CN CN201480061455.2A patent/CN105683162A/zh active Pending
- 2014-11-11 CA CA2929907A patent/CA2929907A1/en not_active Abandoned
- 2014-11-11 HU HUE14799988A patent/HUE041873T2/hu unknown
- 2014-11-11 EP EP14799988.2A patent/EP3068763B1/en active Active
- 2014-11-11 KR KR1020167015530A patent/KR20160083950A/ko not_active Withdrawn
- 2014-11-11 SM SM20190156T patent/SMT201900156T1/it unknown
- 2014-11-11 AU AU2014350334A patent/AU2014350334B2/en not_active Ceased
- 2014-11-11 RU RU2016116955A patent/RU2685408C1/ru not_active IP Right Cessation
- 2014-11-11 LT LTEP14799988.2T patent/LT3068763T/lt unknown
-
2017
- 2017-10-05 US US15/725,429 patent/US20180079722A1/en not_active Abandoned
-
2018
- 2018-12-13 US US16/218,602 patent/US10604485B2/en not_active Expired - Fee Related
-
2019
- 2019-02-26 CY CY20191100237T patent/CY1121581T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI3068763T1 (sl) | 2019-04-30 |
| KR20160083950A (ko) | 2016-07-12 |
| JP6401265B2 (ja) | 2018-10-10 |
| US20180079722A1 (en) | 2018-03-22 |
| RU2016116955A (ru) | 2017-12-19 |
| DK3068763T3 (en) | 2019-03-18 |
| RS58382B1 (sr) | 2019-04-30 |
| TR201902981T4 (tr) | 2019-03-21 |
| ES2714721T3 (es) | 2019-05-29 |
| HRP20190449T1 (hr) | 2019-04-19 |
| US20160264525A1 (en) | 2016-09-15 |
| GB201320021D0 (en) | 2013-12-25 |
| SMT201900156T1 (it) | 2019-05-10 |
| AU2014350334B2 (en) | 2017-08-10 |
| PT3068763T (pt) | 2019-03-20 |
| AU2014350334A1 (en) | 2016-06-02 |
| CY1121581T1 (el) | 2020-05-29 |
| EP3068763B1 (en) | 2018-12-19 |
| RU2685408C1 (ru) | 2019-04-18 |
| LT3068763T (lt) | 2019-03-12 |
| PL3068763T3 (pl) | 2019-05-31 |
| EP3068763A1 (en) | 2016-09-21 |
| JP2016537344A (ja) | 2016-12-01 |
| US10604485B2 (en) | 2020-03-31 |
| US20190112269A1 (en) | 2019-04-18 |
| HUE041873T2 (hu) | 2019-05-28 |
| US9809540B2 (en) | 2017-11-07 |
| CA2929907A1 (en) | 2015-05-21 |
| CN105683162A (zh) | 2016-06-15 |
| BR112016010409A8 (pt) | 2020-04-22 |
| WO2015071235A1 (en) | 2015-05-21 |
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