HRP20190245T1 - Tartratna sol [(s)-2-[metil-3-(2-okso-pirolidin-1-il)-benzensulfonilamino]-3-(4-metil piperazin-1 -il)-3-okso-propril]amida 5-kloro-tiofen-2-karboksilne kiseline - Google Patents

Tartratna sol [(s)-2-[metil-3-(2-okso-pirolidin-1-il)-benzensulfonilamino]-3-(4-metil piperazin-1 -il)-3-okso-propril]amida 5-kloro-tiofen-2-karboksilne kiseline

Info

Publication number
HRP20190245T1
HRP20190245T1 HRP20190245TT HRP20190245T HRP20190245T1 HR P20190245 T1 HRP20190245 T1 HR P20190245T1 HR P20190245T T HRP20190245T T HR P20190245TT HR P20190245 T HRP20190245 T HR P20190245T HR P20190245 T1 HRP20190245 T1 HR P20190245T1
Authority
HR
Croatia
Prior art keywords
oxo
methyl
propryl
benzenesulfonylamino
pyrrolidin
Prior art date
Application number
HRP20190245TT
Other languages
English (en)
Inventor
Laurent Lafferrere
Sébastien VILLION
Sandrine Gauthier
André Bourbon
Original Assignee
Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi filed Critical Sanofi
Publication of HRP20190245T1 publication Critical patent/HRP20190245T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/245Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/255Tartaric acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HRP20190245TT 2013-04-26 2019-02-06 Tartratna sol [(s)-2-[metil-3-(2-okso-pirolidin-1-il)-benzensulfonilamino]-3-(4-metil piperazin-1 -il)-3-okso-propril]amida 5-kloro-tiofen-2-karboksilne kiseline HRP20190245T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13305556 2013-04-26
EP14719340.3A EP2989095B1 (en) 2013-04-26 2014-04-25 Tartrate salt of 5-chloro-thiophene-2-carboxylic acid [(s)-2-[methyl-3-(2-oxo-pyrrolidin-1-yl)-benzenesulfonylamino]-3-(4-methyl piperazin-1 -yl)-3-oxo-propryl]amide
PCT/EP2014/058513 WO2014174102A1 (en) 2013-04-26 2014-04-25 Tartrate salt of 5-chloro-thiophene-2-carboxylic acid [(s)-2-[methyl-3-(2-oxo-pyrrolidin-1-yl)-benzenesulfonylamino]-3-(4-methyl piperazin-1 -yl)-3-oxo-propryl]amide

Publications (1)

Publication Number Publication Date
HRP20190245T1 true HRP20190245T1 (hr) 2019-04-05

Family

ID=48428407

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20190245TT HRP20190245T1 (hr) 2013-04-26 2019-02-06 Tartratna sol [(s)-2-[metil-3-(2-okso-pirolidin-1-il)-benzensulfonilamino]-3-(4-metil piperazin-1 -il)-3-okso-propril]amida 5-kloro-tiofen-2-karboksilne kiseline

Country Status (24)

Country Link
US (1) US9637479B2 (hr)
EP (1) EP2989095B1 (hr)
JP (1) JP6393310B2 (hr)
KR (1) KR102388926B1 (hr)
CN (1) CN105143213B (hr)
AU (1) AU2014259378B2 (hr)
BR (1) BR112015026841A8 (hr)
CA (1) CA2910085C (hr)
CY (1) CY1123536T1 (hr)
DK (1) DK2989095T3 (hr)
ES (1) ES2711144T3 (hr)
HR (1) HRP20190245T1 (hr)
HU (1) HUE042250T2 (hr)
IL (1) IL242081B (hr)
LT (1) LT2989095T (hr)
MX (1) MX360896B (hr)
PL (1) PL2989095T3 (hr)
PT (1) PT2989095T (hr)
RU (1) RU2664538C2 (hr)
SG (1) SG11201508515WA (hr)
SI (1) SI2989095T1 (hr)
TR (1) TR201901931T4 (hr)
TW (1) TWI615390B (hr)
WO (1) WO2014174102A1 (hr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022338082A1 (en) 2021-09-03 2024-02-15 Bayer Aktiengesellschaft Substituted s-alaninate derivatives

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0778835A4 (en) * 1994-08-25 1999-02-03 Univ Virginia 7-AZABICYCLO (2.2.1) -HEPTANE AND -HEPTENE DERIVATIVES AS LIGANDS OF THE CHOLI ENERGY RECEPTORS
JP4160634B2 (ja) * 1996-05-31 2008-10-01 シグマ―タウ インダストゥリー ファーマチェウティケ リウニーテ ソシエタ ペル アチオニ L(―)カルニチンおよびアルカノイルl(―)カルニチン類の安定な非吸湿性塩、それらの製造方法並びに該塩を含有する固形の経口投与可能な組成物
SE510305C2 (sv) * 1997-05-30 1999-05-10 Astra Ab Nytt salt
GB0030304D0 (en) * 2000-12-13 2001-01-24 Lilly Co Eli Compounds
GB0114005D0 (en) * 2001-06-08 2001-08-01 Glaxo Group Ltd Chemical compounds
GB0127568D0 (en) * 2001-11-16 2002-01-09 Glaxo Group Ltd Chemical compounds
GB0228552D0 (en) * 2002-12-06 2003-01-15 Glaxo Group Ltd Chemical compounds
CA2537170A1 (en) * 2003-08-28 2005-03-10 Mayne Pharma Pty Ltd Acid containing oxaliplatin formulations
US7371743B2 (en) * 2004-02-28 2008-05-13 Boehringer Ingelheim International Gmbh Carboxylic acid amides, the preparation thereof and their use as medicaments
JP5422570B2 (ja) * 2008-02-21 2014-02-19 サノフイ 凝固第Xa因子及びトロンビンの阻害剤としてのクロロチオフェン−アミド類
KR100953535B1 (ko) * 2008-07-17 2010-04-21 재단법인 포항산업과학연구원 염소계 화합물을 이용한 배가스 내 수은 제거 방법

Also Published As

Publication number Publication date
RU2015150388A3 (hr) 2018-03-27
KR102388926B1 (ko) 2022-04-22
DK2989095T3 (en) 2019-03-18
CY1123536T1 (el) 2021-10-29
CA2910085C (en) 2021-05-25
ES2711144T3 (es) 2019-04-30
KR20160002952A (ko) 2016-01-08
JP6393310B2 (ja) 2018-09-19
SG11201508515WA (en) 2015-11-27
BR112015026841A2 (pt) 2017-07-25
EP2989095B1 (en) 2018-11-21
AU2014259378A1 (en) 2015-12-10
RU2015150388A (ru) 2017-06-02
CA2910085A1 (en) 2014-10-30
MX360896B (es) 2018-11-21
US9637479B2 (en) 2017-05-02
TW201520208A (zh) 2015-06-01
JP2016518381A (ja) 2016-06-23
MX2015014986A (es) 2016-02-05
SI2989095T1 (sl) 2019-03-29
PL2989095T3 (pl) 2019-07-31
LT2989095T (lt) 2019-03-12
RU2664538C2 (ru) 2018-08-20
CN105143213B (zh) 2018-07-24
US20160102082A1 (en) 2016-04-14
WO2014174102A1 (en) 2014-10-30
AU2014259378B2 (en) 2018-08-30
BR112015026841A8 (pt) 2019-12-24
TR201901931T4 (tr) 2019-03-21
PT2989095T (pt) 2019-02-19
TWI615390B (zh) 2018-02-21
EP2989095A1 (en) 2016-03-02
HUE042250T2 (hu) 2019-06-28
CN105143213A (zh) 2015-12-09
IL242081B (en) 2019-08-29

Similar Documents

Publication Publication Date Title
HUS2200010I1 (hu) Kondenzált heterociklusos vegyületek protein-kináz inhibitorként
HRP20201107T8 (hr) Heteroaril amidi kao inhibitori proteinske agregacije
HK1221606A1 (zh) 纖維化的小分子抑制劑
ZA201502783B (en) Azaquinazoline inhibitors of atypical protein kinase c
IL242239B (en) Co-crystals of dapagliflozin
SG11201507347QA (en) Pharmaceutical composition of s-ketamine hydrochloride
SG11201507358VA (en) Pharmaceutical composition of s-ketamine hydrochloride
EP2968321A4 (en) COMPOUNDS FOR THE TREATMENT OF FIBROSIS DISEASES
HK1204559A1 (en) Solid composition of amino carboxylate salt
PL3063152T3 (pl) Dogodne wytwarzanie n-podstawionych morfinan-6-oli z morfinan-6-onów
HRP20190245T1 (hr) Tartratna sol [(s)-2-[metil-3-(2-okso-pirolidin-1-il)-benzensulfonilamino]-3-(4-metil piperazin-1 -il)-3-okso-propril]amida 5-kloro-tiofen-2-karboksilne kiseline