HRP20182043T1 - Upotreba anti-konfeksinskih sredstava za poboljšanje terapijskog učinka inhibitora acetilkolinesteraze - Google Patents
Upotreba anti-konfeksinskih sredstava za poboljšanje terapijskog učinka inhibitora acetilkolinesterazeInfo
- Publication number
- HRP20182043T1 HRP20182043T1 HRP20182043TT HRP20182043T HRP20182043T1 HR P20182043 T1 HRP20182043 T1 HR P20182043T1 HR P20182043T T HRP20182043T T HR P20182043TT HR P20182043 T HRP20182043 T HR P20182043T HR P20182043 T1 HRP20182043 T1 HR P20182043T1
- Authority
- HR
- Croatia
- Prior art keywords
- enhancing
- therapeutic effect
- acetylcholinesterase inhibitors
- connexin agents
- connexin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/49—Cinchonan derivatives, e.g. quinine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11306407.5A EP2586436A1 (en) | 2011-10-31 | 2011-10-31 | Use of anti-connexin agents for enhancing the therapeutic effect of acetylcholinesterase inhibitor |
| EP12778762.0A EP2773337B1 (en) | 2011-10-31 | 2012-10-31 | Use of anti-connexin agents for enhancing the therapeutic effect of acetylcholinesterase inhibitors |
| PCT/EP2012/071631 WO2013064579A1 (en) | 2011-10-31 | 2012-10-31 | Use of anti-connexin agents for enhancing the therapeutic effect of acetylcholinesterase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20182043T1 true HRP20182043T1 (hr) | 2019-04-19 |
| HRP20182043T8 HRP20182043T8 (hr) | 2019-06-14 |
Family
ID=47080551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20182043TT HRP20182043T8 (hr) | 2011-10-31 | 2018-12-05 | Upotreba anti-koneksinskih sredstava za poboljšanje terapijskog učinka inhibitora acetilkolinesteraze |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20150011584A1 (hr) |
| EP (3) | EP2586436A1 (hr) |
| JP (1) | JP6053805B2 (hr) |
| CN (1) | CN103906511B (hr) |
| AU (2) | AU2012331136B2 (hr) |
| CA (1) | CA2853325C (hr) |
| DK (1) | DK2773337T3 (hr) |
| ES (1) | ES2701048T3 (hr) |
| HR (1) | HRP20182043T8 (hr) |
| HU (1) | HUE042671T2 (hr) |
| IL (2) | IL232292A0 (hr) |
| PL (1) | PL2773337T3 (hr) |
| PT (1) | PT2773337T (hr) |
| WO (1) | WO2013064579A1 (hr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2620363T3 (es) * | 2004-12-21 | 2017-06-28 | Musc Foundation For Research Development | Composiciones y métodos para promover la cicatrización de heridas y la regeneración tisular |
| AU2014295030B2 (en) * | 2013-07-24 | 2017-06-01 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Use of flecainide as an anti-connexin agent and method for potentiating the effects of a psychotropic drug |
| WO2015035258A1 (en) * | 2013-09-06 | 2015-03-12 | The Rockefeller University | Treatment and prevention of autism and autism spectrum disorders |
| JP6914858B2 (ja) * | 2015-06-15 | 2021-08-04 | ラッシュ・ユニバーシティ・メディカル・センター | 脳由来のＰＰＡＲαリガンド |
| US10864192B2 (en) * | 2016-01-15 | 2020-12-15 | Aristea Translational Medicine Corporation | Compositions and methods for inhibiting brain trauma-induced neurodegeneration and related conditions |
| US10111860B1 (en) * | 2016-01-15 | 2018-10-30 | Aristea Translational Medicine Corporation | Compositions and methods for treating concussion |
| KR20200107927A (ko) | 2017-09-28 | 2020-09-16 | 아스데라 엘엘씨 | 인지질 조절장애를 수반하는 질환 및 장애에서의 시클로덱스트린의 용도 |
| EP3593822A1 (en) | 2018-07-13 | 2020-01-15 | Theranexus | Therapeutic and diagnostic applications of a new method of monitoring of neuroglial interaction memri) |
| FR3110393B1 (fr) | 2020-05-20 | 2022-05-06 | Grn Consulting | Compose et composition pour induire une neuroprotection |
| FR3128872A1 (fr) | 2021-11-08 | 2023-05-12 | Rest Therapeutics | Nouvelles combinaisons synergiques a base de fenm |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0975345A1 (en) | 1997-11-26 | 2000-02-02 | Cerebrus Pharmaceuticals Limited | (-)-mefloquine to block purinergic receptors and to treat movement or neurodegenerative disorders |
| US20080021085A1 (en) * | 2000-04-13 | 2008-01-24 | Mayo Foundation For Medical Education And Research | Method of reducing abeta42 and treating diseases |
| JP2003530437A (ja) * | 2000-04-13 | 2003-10-14 | マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ | Ａβ４２低下物質 |
| DE10119862A1 (de) * | 2001-04-24 | 2002-11-07 | Hf Arzneimittelforsch Gmbh | Verwendung von Galanthamin zur Behandlung von Krankheitserscheinungen des zentralen Nervensystems aufgrund von Intoxikationen mit psychotropen Substanzen |
| WO2004091522A2 (en) | 2003-04-11 | 2004-10-28 | Myriad Genetics, Inc. | Method for treating neurodegenerative disorders |
| CA2508585A1 (en) * | 2004-06-01 | 2005-12-01 | Axonyx, Inc. | Transdermal delivery system for treatment of cognitive disorders |
| HUP0401850A3 (en) | 2004-09-15 | 2008-03-28 | Egis Gyogyszergyar Nyilvanosan | Donepezil salts for producing pharmaceutical composition |
| US20060194723A1 (en) * | 2005-02-28 | 2006-08-31 | Rabinoff Michael D | Novel medication treatment and delivery strategies for Alzheimer's Disease, other disorders with memory impairment, and possible treatment strategies for memory improvement |
| US8021701B1 (en) * | 2005-04-13 | 2011-09-20 | Perry Stephen C | Composition to retard the onset of symptoms of alzheimer's disease |
| FR2935611B1 (fr) | 2008-09-10 | 2010-10-15 | Commissariat Energie Atomique | Utilisation d'agents anti-connexines pour moduler l'effet therapeutique de molecules psychotropes |
| CN101991859A (zh) * | 2009-10-27 | 2011-03-30 | 上海复旦复华药业有限公司 | 一种石杉碱甲的β-环糊精包合物及其制备方法和制剂 |
-
2011
- 2011-10-31 EP EP11306407.5A patent/EP2586436A1/en not_active Withdrawn
-
2012
- 2012-10-31 AU AU2012331136A patent/AU2012331136B2/en not_active Ceased
- 2012-10-31 EP EP12778762.0A patent/EP2773337B1/en active Active
- 2012-10-31 CN CN201280053256.8A patent/CN103906511B/zh not_active Expired - Fee Related
- 2012-10-31 JP JP2014537665A patent/JP6053805B2/ja not_active Expired - Fee Related
- 2012-10-31 CA CA2853325A patent/CA2853325C/en active Active
- 2012-10-31 PT PT12778762T patent/PT2773337T/pt unknown
- 2012-10-31 PL PL12778762T patent/PL2773337T3/pl unknown
- 2012-10-31 US US14/355,153 patent/US20150011584A1/en not_active Abandoned
- 2012-10-31 ES ES12778762T patent/ES2701048T3/es active Active
- 2012-10-31 HU HUE12778762A patent/HUE042671T2/hu unknown
- 2012-10-31 DK DK12778762.0T patent/DK2773337T3/en active
- 2012-10-31 WO PCT/EP2012/071631 patent/WO2013064579A1/en active Application Filing
- 2012-10-31 EP EP18195298.7A patent/EP3446688A1/en not_active Withdrawn
-
2014
- 2014-04-28 IL IL232292A patent/IL232292A0/en unknown
-
2017
- 2017-09-11 AU AU2017228472A patent/AU2017228472B2/en not_active Ceased
-
2018
- 2018-02-23 US US15/903,662 patent/US10765670B2/en active Active
- 2018-12-05 HR HRP20182043TT patent/HRP20182043T8/hr unknown
-
2019
- 2019-11-18 IL IL270748A patent/IL270748B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUE042671T2 (hu) | 2019-07-29 |
| IL270748A (en) | 2020-01-30 |
| EP2773337A1 (en) | 2014-09-10 |
| JP2014532635A (ja) | 2014-12-08 |
| AU2012331136B2 (en) | 2017-06-29 |
| HRP20182043T8 (hr) | 2019-06-14 |
| AU2017228472A1 (en) | 2017-10-05 |
| EP3446688A1 (en) | 2019-02-27 |
| AU2017228472B2 (en) | 2019-07-11 |
| EP2773337B1 (en) | 2018-09-19 |
| WO2013064579A1 (en) | 2013-05-10 |
| EP2586436A1 (en) | 2013-05-01 |
| AU2012331136A1 (en) | 2014-05-01 |
| PL2773337T3 (pl) | 2019-04-30 |
| IL270748B (en) | 2021-10-31 |
| CA2853325A1 (en) | 2013-05-10 |
| ES2701048T3 (es) | 2019-02-20 |
| US20180177773A1 (en) | 2018-06-28 |
| JP6053805B2 (ja) | 2016-12-27 |
| CN103906511A (zh) | 2014-07-02 |
| PT2773337T (pt) | 2018-12-20 |
| CN103906511B (zh) | 2016-04-06 |
| US10765670B2 (en) | 2020-09-08 |
| CA2853325C (en) | 2021-08-24 |
| DK2773337T3 (en) | 2018-12-10 |
| US20150011584A1 (en) | 2015-01-08 |
| IL232292A0 (en) | 2014-06-30 |
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