HRP20181265T1 - Mif inhibitori - Google Patents

Mif inhibitori

Info

Publication number
HRP20181265T1
HRP20181265T1 HRP20181265TT HRP20181265T HRP20181265T1 HR P20181265 T1 HRP20181265 T1 HR P20181265T1 HR P20181265T T HRP20181265T T HR P20181265TT HR P20181265 T HRP20181265 T HR P20181265T HR P20181265 T1 HRP20181265 T1 HR P20181265T1
Authority
HR
Croatia
Prior art keywords
mif inhibitors
mif
inhibitors
Prior art date
Application number
HRP20181265TT
Other languages
English (en)
Croatian (hr)
Inventor
Gaël Jalce
Bernardin Akagah
Original Assignee
Mifcare
Gaël Jalce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mifcare, Gaël Jalce filed Critical Mifcare
Publication of HRP20181265T1 publication Critical patent/HRP20181265T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
HRP20181265TT 2014-04-10 2018-08-08 Mif inhibitori HRP20181265T1 (hr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14164210.8A EP2929882B1 (en) 2014-04-10 2014-04-10 MIF inhibitors

Publications (1)

Publication Number Publication Date
HRP20181265T1 true HRP20181265T1 (hr) 2018-11-02

Family

ID=50478272

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20181265TT HRP20181265T1 (hr) 2014-04-10 2018-08-08 Mif inhibitori

Country Status (13)

Country Link
US (1) US10160732B2 (pl)
EP (1) EP2929882B1 (pl)
JP (1) JP6619796B2 (pl)
DK (1) DK2929882T3 (pl)
ES (1) ES2683716T3 (pl)
HK (1) HK1216234A1 (pl)
HR (1) HRP20181265T1 (pl)
HU (1) HUE039739T2 (pl)
PL (1) PL2929882T3 (pl)
PT (1) PT2929882T (pl)
RS (1) RS57649B1 (pl)
TR (1) TR201811441T4 (pl)
WO (1) WO2015155358A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS57649B1 (sr) 2014-04-10 2018-11-30 Mifcare Mif inhibitori
EP2944310B1 (en) * 2014-05-16 2018-03-21 Mifcare MIF inhibitors for the acute or chronic treatment of pulmonary hypertension
EP3506982A4 (en) * 2016-09-02 2020-07-22 The Johns Hopkins University MIF INHIBITORS AND METHOD FOR USE
JP7450980B2 (ja) * 2019-12-10 2024-03-18 シャンハイ ジムン バイオファーマ,インコーポレーテッド 神経保護効果を有する化合物およびその調製方法と用途
CN114195702A (zh) * 2020-09-18 2022-03-18 瑞博(杭州)医药科技有限公司 一种用于合成抗肿瘤药物尼拉帕利的中间体及其制备方法
WO2023198833A1 (en) 2022-04-13 2023-10-19 Apaxen Sa Compound for the inhibition of the nlrp3 inflammasome

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2028083A1 (pl) * 1969-01-10 1970-10-09 Fuji Photo Film Co Ltd
JPS51151134A (en) * 1975-06-19 1976-12-25 Fuji Photo Film Co Ltd Multilayer color photographic light sensitive material
JPS58157718A (ja) * 1982-03-11 1983-09-19 Masatoshi Yamato 抗腫瘍薬
JPS63101380A (ja) * 1986-10-17 1988-05-06 Zeria Shinyaku Kogyo Kk 新規な2−メルカプトベンズイミダゾ−ル誘導体、それらの製造法およびそれらを有効成分として含有する抗潰瘍剤
GB8804457D0 (en) * 1988-02-25 1988-03-23 Ciba Geigy Ag Compositions
EP0394195A3 (de) * 1989-04-18 1992-06-17 Ciba-Geigy Ag Korrosionsbeständige Epoxid- und Polyurethanharzzusammensetzungen
US20050267148A1 (en) * 1998-07-15 2005-12-01 Teijin Limited Benzimidazole derivative
US20120040974A1 (en) 2008-08-18 2012-02-16 Yale University Mif modulators
RS57649B1 (sr) 2014-04-10 2018-11-30 Mifcare Mif inhibitori

Also Published As

Publication number Publication date
TR201811441T4 (tr) 2018-09-21
EP2929882A1 (en) 2015-10-14
HK1216234A1 (zh) 2016-10-28
RS57649B1 (sr) 2018-11-30
EP2929882B1 (en) 2018-06-13
WO2015155358A1 (en) 2015-10-15
PL2929882T3 (pl) 2018-11-30
ES2683716T3 (es) 2018-09-27
PT2929882T (pt) 2018-10-04
HUE039739T2 (hu) 2019-01-28
US10160732B2 (en) 2018-12-25
JP2017510657A (ja) 2017-04-13
JP6619796B2 (ja) 2019-12-11
US20170029387A1 (en) 2017-02-02
DK2929882T3 (en) 2018-08-20

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