HRP20180397T1 - Novi postupci za pripremanje 4-supstituiranih imidazola - Google Patents

Novi postupci za pripremanje 4-supstituiranih imidazola

Info

Publication number
HRP20180397T1
HRP20180397T1 HRP20180397TT HRP20180397T HRP20180397T1 HR P20180397 T1 HRP20180397 T1 HR P20180397T1 HR P20180397T T HRP20180397T T HR P20180397TT HR P20180397 T HRP20180397 T HR P20180397T HR P20180397 T1 HRP20180397 T1 HR P20180397T1
Authority
HR
Croatia
Prior art keywords
preparation
new procedures
substituted imidazoles
imidazoles
substituted
Prior art date
Application number
HRP20180397TT
Other languages
English (en)
Croatian (hr)
Inventor
Lars Eklund
Lars Hansson
Tommy Lundholm
Pär Holmberg
Margus Eek
Original Assignee
Cambrex Karlskoga Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambrex Karlskoga Ab filed Critical Cambrex Karlskoga Ab
Publication of HRP20180397T1 publication Critical patent/HRP20180397T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/02—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
    • C07C47/105—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing rings
    • C07C47/11—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing rings monocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/228—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HRP20180397TT 2011-07-22 2012-07-20 Novi postupci za pripremanje 4-supstituiranih imidazola HRP20180397T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161510538P 2011-07-22 2011-07-22
EP12766318.5A EP2734508B1 (en) 2011-07-22 2012-07-20 New processes for preparing 4-substituted imidazoles
PCT/GB2012/051746 WO2013014428A1 (en) 2011-07-22 2012-07-20 New processes for preparing 4-substituted imidazoles

Publications (1)

Publication Number Publication Date
HRP20180397T1 true HRP20180397T1 (hr) 2018-05-18

Family

ID=46939718

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20180397TT HRP20180397T1 (hr) 2011-07-22 2012-07-20 Novi postupci za pripremanje 4-supstituiranih imidazola

Country Status (13)

Country Link
US (1) US8962862B2 (Direct)
EP (1) EP2734508B1 (Direct)
JP (1) JP5996647B2 (Direct)
KR (1) KR101932206B1 (Direct)
CN (1) CN103748077B (Direct)
DK (1) DK2734508T3 (Direct)
ES (1) ES2665093T3 (Direct)
HR (1) HRP20180397T1 (Direct)
HU (1) HUE037591T2 (Direct)
IN (1) IN2014DN00144A (Direct)
NO (1) NO2650436T3 (Direct)
PL (1) PL2734508T3 (Direct)
WO (1) WO2013014428A1 (Direct)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103588711B (zh) 2013-11-27 2015-04-08 天津炜捷制药有限公司 一种美托咪定中间体的制备方法
GB201501593D0 (en) 2015-01-30 2015-03-18 Cambrex Karlskoga Ab New compounds and processes
KR101940662B1 (ko) 2017-08-11 2019-01-22 충남대학교산학협력단 직류전원 공급부를 가지는 산화제 과잉환경 시험장치
KR101940663B1 (ko) 2017-08-11 2019-01-22 충남대학교산학협력단 촉매 반응부를 가지는 산화제 과잉 시험장치
US12050293B2 (en) 2018-12-19 2024-07-30 Pgs Geophysical As Medetomidine compositions having improved anti-fouling characteristics
WO2022086416A1 (en) 2020-10-21 2022-04-28 I-Tech Ab Antifouling compounds
EP4506340A1 (en) 2022-03-22 2025-02-12 Obshestvo s Ogranichennoj Otvetstvennostju "Vikzdorove Zhivotnyh" Method for producing medetomidine and its derivatives
EP4580398A1 (en) 2022-09-01 2025-07-09 I-Tech AB Composition protecting wood against marine woodborers
CN115745893A (zh) * 2022-11-16 2023-03-07 西安近代化学研究所 一种合成2-氰基-5-芳基-1h-咪唑类化合物的方法
WO2026015064A1 (en) 2024-07-09 2026-01-15 I-Tech Ab Antifouling paint composition with improved in-can stability

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2016809C3 (de) 1969-04-10 1974-05-16 S.A. Prb, Bruessel Verfahren zur Herstellung von Arylierungsprodukten olefinisch ungesättigter Verbindungen
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
SI1311488T1 (sl) * 2000-08-17 2010-01-29 Pfizer Ltd Substituirani imidazoli kot inhibitorji TAFIA
EP1918282A1 (en) 2006-11-06 2008-05-07 "Joint Stock Company Grindeks" Method for preparing medetomidine and its salts
EP2162441B1 (en) * 2007-05-24 2016-01-06 Eldrug S.A. 1,(3,)5-substituted imidazoles, useful in the treatment of hypertension and methods for their preparation
GB2453982B (en) * 2007-10-24 2009-09-16 Norbrook Lab Ltd Chemical process for the preparation of Medetomidine
CN101921234B (zh) * 2009-06-12 2012-05-30 中国中化股份有限公司 一种制备美托咪啶的方法
CN102753532B (zh) 2009-12-09 2015-05-13 I-技术有限公司 美托咪定的制备方法

Also Published As

Publication number Publication date
WO2013014428A1 (en) 2013-01-31
CN103748077B (zh) 2016-08-17
KR20140068888A (ko) 2014-06-09
KR101932206B1 (ko) 2018-12-24
PL2734508T3 (pl) 2018-08-31
US20140187789A1 (en) 2014-07-03
US8962862B2 (en) 2015-02-24
ES2665093T3 (es) 2018-04-24
JP2014520901A (ja) 2014-08-25
EP2734508B1 (en) 2018-02-28
EP2734508A1 (en) 2014-05-28
NO2650436T3 (Direct) 2018-03-10
HUE037591T2 (hu) 2018-09-28
IN2014DN00144A (Direct) 2015-05-22
JP5996647B2 (ja) 2016-09-21
DK2734508T3 (en) 2018-05-22
CN103748077A (zh) 2014-04-23

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