HRP20170238T1 - Postupak za pripremu vodenih otopina hiperpolariziranih molekula - Google Patents

Postupak za pripremu vodenih otopina hiperpolariziranih molekula

Info

Publication number
HRP20170238T1
HRP20170238T1 HRP20170238TT HRP20170238T HRP20170238T1 HR P20170238 T1 HRP20170238 T1 HR P20170238T1 HR P20170238T T HRP20170238T T HR P20170238TT HR P20170238 T HRP20170238 T HR P20170238T HR P20170238 T1 HRP20170238 T1 HR P20170238T1
Authority
HR
Croatia
Prior art keywords
preparation
aqueous solutions
hyperpolarized molecules
hyperpolarized
molecules
Prior art date
Application number
HRP20170238TT
Other languages
English (en)
Inventor
Francesca Reineri
Alessandra Viale
Giovanni Battista Giovenzana
Daniela Santelia
Walter Dastru'
Roberto Gobetto
Silvio Aime
Fulvio Uggeri
Original Assignee
Bracco Imaging S.P.A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI2008A001765A external-priority patent/IT1391330B1/it
Priority claimed from ITMI2009A000942A external-priority patent/IT1395345B1/it
Application filed by Bracco Imaging S.P.A filed Critical Bracco Imaging S.P.A
Publication of HRP20170238T1 publication Critical patent/HRP20170238T1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
HRP20170238TT 2008-10-03 2017-02-14 Postupak za pripremu vodenih otopina hiperpolariziranih molekula HRP20170238T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ITMI2008A001765A IT1391330B1 (it) 2008-10-03 2008-10-03 Processo per la preparazione di molecole iperpolarizzate.
ITMI2009A000942A IT1395345B1 (it) 2009-05-28 2009-05-28 Processo per la preparazione di molecole iperpolarizzate
EP09783592.0A EP2349350B1 (en) 2008-10-03 2009-09-30 A process for the preparation of aqueous solutions of hyperpolarized molecules
PCT/EP2009/062674 WO2010037771A1 (en) 2008-10-03 2009-09-30 A process for the preparation of aqueous solutions of hyperpolarized molecules

Publications (1)

Publication Number Publication Date
HRP20170238T1 true HRP20170238T1 (hr) 2017-04-07

Family

ID=41571789

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20170238TT HRP20170238T1 (hr) 2008-10-03 2017-02-14 Postupak za pripremu vodenih otopina hiperpolariziranih molekula

Country Status (13)

Country Link
US (1) US8961933B2 (hr)
EP (1) EP2349350B1 (hr)
JP (1) JP5518874B2 (hr)
CN (1) CN102170914B (hr)
DK (1) DK2349350T3 (hr)
ES (1) ES2616265T3 (hr)
HR (1) HRP20170238T1 (hr)
HU (1) HUE031915T2 (hr)
IL (1) IL212117A0 (hr)
PL (1) PL2349350T3 (hr)
PT (1) PT2349350T (hr)
SI (1) SI2349350T1 (hr)
WO (1) WO2010037771A1 (hr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009129265A1 (en) * 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization
WO2011124672A1 (en) * 2010-04-08 2011-10-13 Bracco Imaging Spa Process for preparing hyperpolarized substrates and method for mri
US9511154B2 (en) 2011-10-12 2016-12-06 Bracco Imaging S.P.A. Process for the preparation of hyperpolarized derivatives for use in MRI analysis
US9693828B2 (en) 2011-12-05 2017-07-04 Bracco Imaging S.P.A. Composition comprising acetic anhydride and a gadolinium complex, and method for the use in hyperpolarisation in MRI analysis
WO2015063020A1 (en) * 2013-10-28 2015-05-07 Bracco Imaging Spa Process for the preparation of hyperpolarized carboxylate compounds
DE102016125583A1 (de) * 2016-12-23 2018-06-28 Stefan Glöggler Verfahren zur Herstellung eines Kontrastmittels für die MR-Spektroskopie
GB201703658D0 (en) * 2017-03-07 2017-04-19 Univ York Hyperpolarization in aqueous media via SABRE
GB201710677D0 (en) * 2017-07-03 2017-08-16 Univ York Polorisation transfer via a second metal complex
WO2019071090A1 (en) * 2017-10-06 2019-04-11 University Of Florida Research Foundation METHODS AND SYSTEMS FOR PRODUCTION, USE, AND ADMINISTRATION OF HYPERPOLARIZED FLUIDS
US11571686B2 (en) 2019-02-15 2023-02-07 Board Of Trustees Of Southern Illinois University Removal of homogeneous catalysts from NMR/MRI agents hyperpolarized via sabre or PHIP
EP4313174A1 (en) * 2021-03-23 2024-02-07 NVision Imaging Technologies GmbH Systems and method for generation of hyperpolarized materials

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3615723A (en) 1970-04-15 1971-10-26 Pillsbury Co Spray-drying apparatus
US5334791A (en) * 1992-05-22 1994-08-02 Ligands Inc. Hydrogenation process with transition metal catalysts derived from bifunctional phosphorus-nitrogen ligands
GB9614139D0 (en) 1996-07-05 1996-09-04 Nycomed Imaging As Method
WO1999024080A1 (en) * 1997-11-12 1999-05-20 Nycomed Imaging As Para-hydrogen labelled agents and their use in magnetic resonance imaging
GB9911681D0 (en) 1999-05-19 1999-07-21 Nycomed Imaging As Process
ES2654520T3 (es) * 2005-10-11 2018-02-14 Huntington Medical Research Institutes Agentes de formación de imágenes y métodos de uso de los mismos
WO2009129265A1 (en) * 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization

Also Published As

Publication number Publication date
PT2349350T (pt) 2017-01-23
PL2349350T3 (pl) 2017-05-31
WO2010037771A1 (en) 2010-04-08
CN102170914B (zh) 2016-02-10
US20110178393A1 (en) 2011-07-21
JP5518874B2 (ja) 2014-06-11
EP2349350B1 (en) 2016-11-30
ES2616265T3 (es) 2017-06-12
DK2349350T3 (en) 2017-02-27
CN102170914A (zh) 2011-08-31
JP2012504438A (ja) 2012-02-23
US8961933B2 (en) 2015-02-24
HUE031915T2 (en) 2017-08-28
SI2349350T1 (sl) 2017-03-31
IL212117A0 (en) 2011-07-31
EP2349350A1 (en) 2011-08-03

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