HRP20161252T1 - Nosač stanica koji sadrži kolagen - Google Patents
Nosač stanica koji sadrži kolagen Download PDFInfo
- Publication number
- HRP20161252T1 HRP20161252T1 HRP20161252TT HRP20161252T HRP20161252T1 HR P20161252 T1 HRP20161252 T1 HR P20161252T1 HR P20161252T T HRP20161252T T HR P20161252TT HR P20161252 T HRP20161252 T HR P20161252T HR P20161252 T1 HRP20161252 T1 HR P20161252T1
- Authority
- HR
- Croatia
- Prior art keywords
- approximately
- preparation
- use according
- biological material
- radiation
- Prior art date
Links
- 102000008186 Collagen Human genes 0.000 title claims 2
- 108010035532 Collagen Proteins 0.000 title claims 2
- 229920001436 collagen Polymers 0.000 title claims 2
- 238000002360 preparation method Methods 0.000 claims 16
- 239000012620 biological material Substances 0.000 claims 5
- 230000005855 radiation Effects 0.000 claims 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 235000011187 glycerol Nutrition 0.000 claims 1
- 239000004519 grease Substances 0.000 claims 1
- 238000011534 incubation Methods 0.000 claims 1
- 230000005865 ionizing radiation Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 239000002243 precursor Substances 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 238000004659 sterilization and disinfection Methods 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
- 235000015112 vegetable and seed oil Nutrition 0.000 claims 1
- 239000008158 vegetable oil Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Botany (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Claims (11)
1. Uporaba pripravka za kultiviranje bioloških stanica, naznačena time da navedeni pripravak sadrži slijedeće parametre:
Kolagen [tež. -%]: približno 50 do 70,
Amidni dušik [tež. -%]: približno 0.14 do 0.4,
Glicerin [tež. -%]: približno 12 do 35,
Mast [tež. -%]: približno 3 do 7,
Sorbit [tež. -%]: približno 0 do 20,
Pepeo [tež. -%]: približno 0.5 do 3,
Voda [tež. -%]: približno 12 do 18,
pH vrijednost: približno 5.5 do 8,
Težina po jedinici površine [g/m2]: približno 20 do 40,
Vlačna čvrstoća [N/mm2]: približno 5 do 25.
2. Uporaba prema zahtjevu 1, naznačena time da je mast uglavnom biljno ulje.
3. Uporaba prema bilo kojem od prethodnih zahtjeva, naznačena time da je pH vrijednost kod približno 6.8 do 8.0, poželjno kod približno 7.0 do 7.8, poželjnije kod približno 7.2 do 7.5.
4. Uporaba prema bilo kojem od prethodnih zahtjeva, naznačena time da je pripravak konfiguriran kao ravni film, ili kao cjevasta ljuska.
5. Uporaba prema bilo kojem od prethodnih zahtjeva, naznačena time da pripravak u suhom stanju ima debljinu od približno 5 do 200 µm, poželjno od približno 10 do µm, najpoželjnije od približno 15 µm.
6. Uporaba prema bilo kojem od prethodnih zahtjeva, naznačena time da je pripravak konfiguriran kao nosač za primjenu za kultiviranje stanica.
7. Uporaba prema bilo kojem od prethodnih zahtjeva, naznačena time da je pripravak konfiguriran kao nosač za implantiranje biološkog materijala, poželjno matičnih prekursorskih stanica, u organizam.
8. Uporaba prema bilo kojem od prethodnih zahtjeva, naznačena time da je pripravak steriliziran pomoću zračenja, pri čemu navedena sterilizacija zračenjem se provodi korištenjem ionizirajućeg zračenja, koje je nadalje poželjno beta-zračenje i/ili gama zračenje.
9. Uporaba prema bilo kojem od prethodnih zahtjeva, naznačena time da pripravak prema izumu sadrži boju, poželjno fluorescentno-apsorbirajuću boju.
10. Uporaba pripravka za određivanje invazivnosti i metastazirajućeg potencijala tumorskih stanica, naznačena time da pripravak koji se koristi je pripravak za uporabu prema bilo kojem od zahtjeva 1 do 9.
11. Postupak za kultiviranje biološkog materijala, koji sadrži slijedeće korake:
(1) osiguravanje pripravka pogodnog za korištenje kao nosača za biološki materijal,
(2) dovođenje u kontakt biološkog materijala s pripravkom, te
(3) inkubaciju pripravka s biološkim materijalom pod kultivacijskim uvjetima,
naznačen time da pripravak koji se koristi je pripravak za uporabu prema bilo kojem od zahtjeva 1 do 9.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007040370A DE102007040370B4 (de) | 2007-08-20 | 2007-08-20 | Kollagenhaltiger Zellträger |
| EP08801567.2A EP2185684B8 (de) | 2007-08-20 | 2008-08-13 | Kollagenhaltiger zellträger |
| PCT/EP2008/006660 WO2009024280A2 (de) | 2007-08-20 | 2008-08-13 | Kollagenhaltiger zellträger |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20161252T1 true HRP20161252T1 (hr) | 2016-11-04 |
Family
ID=39971020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20161252TT HRP20161252T1 (hr) | 2007-08-20 | 2016-09-30 | Nosač stanica koji sadrži kolagen |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US20100233140A1 (hr) |
| EP (2) | EP3098305B8 (hr) |
| JP (1) | JP5638950B2 (hr) |
| KR (2) | KR101685751B1 (hr) |
| CN (1) | CN101790581B (hr) |
| AU (1) | AU2008290857B2 (hr) |
| BR (1) | BRPI0815761B1 (hr) |
| CA (2) | CA2842980C (hr) |
| CY (1) | CY1118101T1 (hr) |
| DE (1) | DE102007040370B4 (hr) |
| DK (1) | DK2185684T3 (hr) |
| ES (2) | ES2710280T3 (hr) |
| HR (1) | HRP20161252T1 (hr) |
| HU (1) | HUE029031T2 (hr) |
| IL (2) | IL203762A (hr) |
| LT (1) | LT2185684T (hr) |
| MX (1) | MX2010001996A (hr) |
| PL (1) | PL2185684T3 (hr) |
| PT (1) | PT2185684T (hr) |
| RU (2) | RU2511426C2 (hr) |
| SI (1) | SI2185684T1 (hr) |
| TW (1) | TWI432571B (hr) |
| WO (1) | WO2009024280A2 (hr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2221362A1 (en) * | 2009-02-19 | 2010-08-25 | Naturin GmbH & Co | Method for the cryopreservation of cells, artificial cell constructs or three-dimensional complex tissues assemblies |
| KR102238108B1 (ko) * | 2010-11-10 | 2021-04-12 | 인리젠 | 장기 확대를 위한 주사가능 제제 |
| US9238090B1 (en) | 2014-12-24 | 2016-01-19 | Fettech, Llc | Tissue-based compositions |
| EP3483253A1 (en) * | 2017-11-08 | 2019-05-15 | Viscofan, S.A. | Cellularized collagen membranes into cell culture bag |
| JP7414224B2 (ja) * | 2018-06-29 | 2024-01-16 | 国立研究開発法人量子科学技術研究開発機構 | 細胞培養用ハイドロゲル、ゲルキット、細胞培養物の製造方法、及び細胞培養用ハイドロゲルの製造方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4996154A (en) * | 1989-05-04 | 1991-02-26 | Millipore Corporation | Method for growing cellular tissue |
| ES2017564A6 (es) | 1989-10-19 | 1991-02-16 | Conservera Campofrio S A | Procedimiento de obtencion de una pasta de colageno. |
| JPH0789842B2 (ja) * | 1992-07-17 | 1995-10-04 | 新田ゼラチン株式会社 | コラーゲンケーシングの製造方法 |
| DE4227681C2 (de) * | 1992-08-21 | 1995-05-18 | Becker & Co Naturinwerk | Wundabdeckungsmaterial auf der Basis von Kollagenfasern und Verfahren zu seiner Herstellung |
| JPH07178A (ja) * | 1993-06-11 | 1995-01-06 | New Japan Chem Co Ltd | 細胞培養用担体 |
| JPH07135961A (ja) * | 1993-11-19 | 1995-05-30 | Sumitomo Bakelite Co Ltd | 血管内皮細胞培養用基材及びその製造方法 |
| DE19504704B4 (de) * | 1995-02-13 | 2005-09-15 | Naturin Gmbh & Co | Eßbare Kollagenhülle, Verfahren zur Herstellung sowie die Verwendung derselben |
| US6482240B1 (en) * | 1999-12-07 | 2002-11-19 | Ed. Geistlich Soehne Ag Fur Chemische Industrie | Method of making a collagen membrane from porcine skin |
| DE10196234B4 (de) * | 2000-05-26 | 2008-04-30 | Engelhard Lyon S.A. | Verfahren zur Herstellung eines Verbundprodukts aus Kollagen für die Gewebebildung und seine Verwendung |
| WO2001092322A1 (fr) * | 2000-05-26 | 2001-12-06 | Coletica | Utilisation de collagene d'origine aquatique pour la realisation de supports destines a l'ingenierie tissulaire, et supports et biomateriaux obtenus |
| US6974679B2 (en) * | 2000-05-26 | 2005-12-13 | Coletica | Support with collagen base for tissue engineering and manufacture of biomaterials |
| US6790454B1 (en) * | 2000-05-26 | 2004-09-14 | Coletica | Processes for the preparation of novel collagen-based supports for tissue engineering, and biomaterials obtained |
| CA2438904C (en) * | 2001-02-23 | 2012-09-04 | The University Of Pittsburgh | Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair |
| CA2388723C (en) * | 2001-06-06 | 2012-10-23 | Becton, Dickinson & Company | Method of providing a substrate with a ready-to-use, uniformly distributed extracellular matrix |
| RU2319709C2 (ru) * | 2001-07-17 | 2008-03-20 | Рисерч Дивелопмент Фаундейшн | Терапевтические агенты, содержащие проапоптозные белки |
| EP1420650B1 (en) * | 2001-08-21 | 2007-11-28 | NATURIN GmbH & CO. | Multi-perforated collagen film |
| GB0120756D0 (en) * | 2001-08-25 | 2001-10-17 | Devro Plc | Collagen casing |
| DE10146445A1 (de) * | 2001-09-20 | 2003-04-24 | Aventis Pharma Gmbh | Optimierung der Temperaturshiftung bei Hochzelldichtefermentationen |
| US7294348B2 (en) * | 2001-09-28 | 2007-11-13 | Biopharma Development, Ltd. | Polyfunctional biocompatible hydrogel and method for the production thereof |
| CA2565203A1 (en) * | 2004-03-31 | 2005-10-20 | Cook Incorporated | Ecm-based graft material |
| US20060121006A1 (en) * | 2004-09-10 | 2006-06-08 | Chancellor Michael B | Production of nutritional and therapeutic products from cultured animal cells |
| FR2877669B1 (fr) * | 2004-11-05 | 2007-01-26 | Inst Nat Sciences Appliq | Greffage covalent de substances hydrophobes sur le collagene |
| US7513866B2 (en) * | 2004-10-29 | 2009-04-07 | Depuy Products, Inc. | Intestine processing device and associated method |
| US7691095B2 (en) | 2004-12-28 | 2010-04-06 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Bi-directional steerable catheter control handle |
| EP2221362A1 (en) * | 2009-02-19 | 2010-08-25 | Naturin GmbH & Co | Method for the cryopreservation of cells, artificial cell constructs or three-dimensional complex tissues assemblies |
| RU89100U1 (ru) * | 2009-07-15 | 2009-11-27 | Сергей Константинович Гордеев | Носитель для культивирования клеток |
-
2007
- 2007-08-20 DE DE102007040370A patent/DE102007040370B4/de active Active
-
2008
- 2008-08-13 CA CA2842980A patent/CA2842980C/en active Active
- 2008-08-13 BR BRPI0815761-8A patent/BRPI0815761B1/pt active IP Right Grant
- 2008-08-13 ES ES16178934T patent/ES2710280T3/es active Active
- 2008-08-13 SI SI200831681A patent/SI2185684T1/sl unknown
- 2008-08-13 ES ES08801567.2T patent/ES2597434T3/es active Active
- 2008-08-13 LT LTEP08801567.2T patent/LT2185684T/lt unknown
- 2008-08-13 KR KR1020137020743A patent/KR101685751B1/ko active IP Right Grant
- 2008-08-13 CN CN200880103577.8A patent/CN101790581B/zh active Active
- 2008-08-13 WO PCT/EP2008/006660 patent/WO2009024280A2/de active Application Filing
- 2008-08-13 AU AU2008290857A patent/AU2008290857B2/en active Active
- 2008-08-13 EP EP16178934.2A patent/EP3098305B8/de active Active
- 2008-08-13 HU HUE08801567A patent/HUE029031T2/en unknown
- 2008-08-13 JP JP2010521341A patent/JP5638950B2/ja active Active
- 2008-08-13 RU RU2010109992/10A patent/RU2511426C2/ru not_active IP Right Cessation
- 2008-08-13 KR KR20107006028A patent/KR101497173B1/ko active IP Right Grant
- 2008-08-13 CA CA2696580A patent/CA2696580C/en active Active
- 2008-08-13 MX MX2010001996A patent/MX2010001996A/es active IP Right Grant
- 2008-08-13 PL PL08801567T patent/PL2185684T3/pl unknown
- 2008-08-13 PT PT88015672T patent/PT2185684T/pt unknown
- 2008-08-13 DK DK08801567.2T patent/DK2185684T3/en active
- 2008-08-13 EP EP08801567.2A patent/EP2185684B8/de active Active
- 2008-08-19 TW TW097131508A patent/TWI432571B/zh not_active IP Right Cessation
-
2010
- 2010-02-07 IL IL203762A patent/IL203762A/en active IP Right Grant
- 2010-02-15 US US12/705,682 patent/US20100233140A1/en not_active Abandoned
-
2013
- 2013-01-04 US US13/734,120 patent/US20130122078A1/en not_active Abandoned
- 2013-09-04 RU RU2013140791/10A patent/RU2577974C2/ru not_active IP Right Cessation
-
2014
- 2014-01-14 IL IL230453A patent/IL230453A/en active IP Right Grant
-
2016
- 2016-09-30 HR HRP20161252TT patent/HRP20161252T1/hr unknown
- 2016-10-13 CY CY20161101031T patent/CY1118101T1/el unknown
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