HRP20150100T1 - Pripravci za simptomatsko olakšavanje boli u želucu ili gastroezofagealnog refluksa - Google Patents
Pripravci za simptomatsko olakšavanje boli u želucu ili gastroezofagealnog refluksa Download PDFInfo
- Publication number
- HRP20150100T1 HRP20150100T1 HRP20150100TT HRP20150100T HRP20150100T1 HR P20150100 T1 HRP20150100 T1 HR P20150100T1 HR P20150100T T HRP20150100T T HR P20150100TT HR P20150100 T HRP20150100 T HR P20150100T HR P20150100 T1 HRP20150100 T1 HR P20150100T1
- Authority
- HR
- Croatia
- Prior art keywords
- preparation according
- fatty acid
- composition according
- sodium
- acid
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 6
- 208000021302 gastroesophageal reflux disease Diseases 0.000 title claims 5
- 206010000087 Abdominal pain upper Diseases 0.000 title 1
- 238000002360 preparation method Methods 0.000 claims 9
- 235000014113 dietary fatty acids Nutrition 0.000 claims 5
- 229930195729 fatty acid Natural products 0.000 claims 5
- 239000000194 fatty acid Substances 0.000 claims 5
- 150000004665 fatty acids Chemical class 0.000 claims 5
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 3
- 239000006000 Garlic extract Substances 0.000 claims 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 3
- 229910052791 calcium Inorganic materials 0.000 claims 3
- 239000011575 calcium Substances 0.000 claims 3
- 235000020706 garlic extract Nutrition 0.000 claims 3
- -1 glycerol ester Chemical class 0.000 claims 3
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims 3
- 229910052708 sodium Inorganic materials 0.000 claims 3
- 239000011734 sodium Substances 0.000 claims 3
- 241000123646 Allioideae Species 0.000 claims 2
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 2
- 239000003513 alkali Substances 0.000 claims 2
- 150000001342 alkaline earth metals Chemical class 0.000 claims 2
- 230000029087 digestion Effects 0.000 claims 2
- 230000001079 digestive effect Effects 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 210000000981 epithelium Anatomy 0.000 claims 2
- 210000004211 gastric acid Anatomy 0.000 claims 2
- 210000001156 gastric mucosa Anatomy 0.000 claims 2
- 230000013632 homeostatic process Effects 0.000 claims 2
- KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical compound CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000419 plant extract Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 235000006708 antioxidants Nutrition 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 150000005323 carbonate salts Chemical class 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000007884 disintegrant Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 238000005538 encapsulation Methods 0.000 claims 1
- 239000000945 filler Substances 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 235000003599 food sweetener Nutrition 0.000 claims 1
- 239000003205 fragrance Substances 0.000 claims 1
- 150000002314 glycerols Chemical class 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 125000002467 phosphate group Chemical class [H]OP(=O)(O[H])O[*] 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- MFBOGIVSZKQAPD-UHFFFAOYSA-M sodium butyrate Chemical compound [Na+].CCCC([O-])=O MFBOGIVSZKQAPD-UHFFFAOYSA-M 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000003765 sweetening agent Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 1
- 239000008513 turmeric extract Substances 0.000 claims 1
- 229940052016 turmeric extract Drugs 0.000 claims 1
- 235000020240 turmeric extract Nutrition 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (15)
1. Pripravak koji sadrži:
- barem jednu C1-C10 masnu kiselinu iz skupine koja obuhvaća maslačnu kiselinu ili izomaslačnu kiselinu, same ili u kombinaciji, ili njihove soli s alkalijskim ili zemnoalkalijskim metalima, ili njihove glicerolske estere, i
- barem jedan biljni ekstrakt iz porodice alliaceae.
2. Pripravak prema zahtjevu 1, gdje je biljni ekstrakt iz porodice alliaceae ekstrakt češnjaka.
3. Pripravak prema zahtjevu 2, gdje je ekstrakt češnjaka suhi ekstrakt češnjaka, u prahu, bez dodanih mirisa.
4. Pripravak prema bilo kojem od zahtjeva 1 do 3, gdje je sol s alkalijskim ili zemnoalkalijskim metalima, barem jedne C1-C10 masne kiseline, natrijeva, kalcijeva ili kalijeva sol.
5. Pripravak prema zahtjevu 4, gdje je natrijeva, kalcijeva ili kalijeva sol C1-C10 masne kiseline natrijev butirat.
6. Pripravak prema bilo kojem od zahtjeva 4 ili 5, gdje je natrijeva, kalcijeva ili kalijeva sol C1-C10 masne kiseline puferirana puferom izabranim između fosfatnih soli i karbonatnih soli.
7. Pripravak prema bilo kojem od zahtjeva 1 do 3, gdje je glicerolni ester barem jedne C1-C10 masne kiseline njezin triglicerid.
8. Pripravak prema bilo kojem od prethodnih zahtjeva, dalje sadrži ekstrat kurkume.
9. Pripravak prema bilo kojem od prethodnih zahtjeva, dalje sadrži barem jednu pomoćnu tvar izabranu iz skupine koja obuhvaća nosače, razrjeđivače, sredstva za raspadanje, lubrikante, veziva, gelante, arome, zaslađivače, bojila, konzervanse, punila, antioksidanse, koadjuvanse za kapsuliranje i sredstva za oblaganje.
10. Pripravak prema bilo kojem od prethodnih zahtjeva, koji dolazi u obliku kapsule, pilule, vrećice, tablete ili obložene tablete.
11. Pripravak prema bilo kojem od prethodnih zahtjeva za ponovno uspostavljanje homeostaze probave koja je poremećena zbog poremećaja želučane kiseline i/ili stanja koja su uzrokovana oštećenjem želučane sluznice ili probavnog epitela.
12. Pripravak prema bilo kojem od zahtjeva 1-10 za olakšavanje gastroezofagealnog refluksa ili GERD simptoma.
13. Uporaba pripravka prema bilo kojem od prethodnih zahtjeva 1-10 u proizvodnji dodatka prehrani.
14. Uporaba pripravka prema bilo kojem od prethodnih zahtjeva 1-10 u proizvodnji lijeka.
15. Uporaba prema zahtjevu 14, gdje je lijek za ponovno uspostavljanje homeostaze probave koja je poremećena zbog poremećaja želučane kiseline i/ili stanja koja su uzrokovana oštećenjem želučane sluznice ili probavnog epitela, kao što je gastroezofagealni refluks ili GERD.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/ES2010/070261 WO2011135107A1 (es) | 2010-04-26 | 2010-04-26 | Composiciones para el alivio sintomático del dolor de estómago o reflujo gastroesofágico |
EP10724102.8A EP2564840B1 (en) | 2010-04-26 | 2010-04-26 | Compositions for the symptomatic relief of stomach pain or gastro-oesophageal reflux |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20150100T1 true HRP20150100T1 (hr) | 2015-05-08 |
Family
ID=43383642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20150100TT HRP20150100T1 (hr) | 2010-04-26 | 2015-01-28 | Pripravci za simptomatsko olakšavanje boli u želucu ili gastroezofagealnog refluksa |
Country Status (11)
Country | Link |
---|---|
US (2) | US20130115290A1 (hr) |
EP (1) | EP2564840B1 (hr) |
CY (1) | CY1115996T1 (hr) |
DK (1) | DK2564840T3 (hr) |
ES (1) | ES2530729T3 (hr) |
HR (1) | HRP20150100T1 (hr) |
PL (1) | PL2564840T3 (hr) |
PT (1) | PT2564840E (hr) |
SI (1) | SI2564840T1 (hr) |
SM (1) | SMT201500033B (hr) |
WO (1) | WO2011135107A1 (hr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109890411A (zh) * | 2016-06-16 | 2019-06-14 | 国际艾滋病疫苗行动组织公司 | 结核病组合物和治疗或预防结核病的方法 |
US11633486B2 (en) | 2017-04-17 | 2023-04-25 | The University Of Chicago | Polymer materials for delivery of short-chain fatty acids to the intestine for applications in human health and treatment of disease |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2608252B2 (ja) * | 1994-09-16 | 1997-05-07 | 名古屋製酪株式会社 | ニンニクの加工処理方法およびアホエン含有油脂の製造方法 |
US5989560A (en) * | 1997-12-03 | 1999-11-23 | Renew Life, Inc. | Herbal intestinal tract cleanser |
US6613356B1 (en) * | 2000-10-10 | 2003-09-02 | Victor Vlahakos | Weight loss medication and method |
AU2003211635A1 (en) * | 2002-03-04 | 2003-09-16 | The Nisshin Oillio Group, Ltd | Uncoupling protein expression promoter |
WO2004069262A1 (en) * | 2003-02-07 | 2004-08-19 | Orchid Chemicals & Pharmaceuticals Ltd | Herbal composition comprising commiphora mukul, allium sativum and curcuma longa |
US20050013921A1 (en) * | 2003-07-17 | 2005-01-20 | Peticca Andrea Lynn | Novel multi-component garlic food supplement |
US7344738B2 (en) * | 2005-11-28 | 2008-03-18 | Sahajanand Biotech Pvt. Ltd. | Herbal composition for treatment of immunocompromised conditions |
EP1859786A1 (en) | 2006-05-16 | 2007-11-28 | Frutarom Netherlands B.V. | A method to reduce the symptoms of heartburn and gastro-oesophageal reflux disease (GERD) by specific polysaccharides |
PL216229B1 (pl) | 2007-01-25 | 2014-03-31 | Biolek Społka Z Ograniczoną Odpowiedzialnością | Preparat zawierający maślan sodu i zastosowanie preparatu zawierającego maślan sodu |
US20090208588A1 (en) | 2008-02-19 | 2009-08-20 | Roger Wayne Brown | GERD carbohydrate compositions |
EP2263666A4 (en) | 2008-03-11 | 2011-11-09 | Ajinomoto Kk | MEDICINE AND FOOD FOR PREVENTING / TREATING FUNCTIONAL STOMACH DISEASES |
IT1392214B1 (it) * | 2008-11-28 | 2012-02-22 | Sila S R L | Processo per la produzione di un composto dell'acido n-butirrico in forma microincapsulata, destinato ad alimentazione animale od umana |
-
2010
- 2010-04-26 WO PCT/ES2010/070261 patent/WO2011135107A1/es active Application Filing
- 2010-04-26 DK DK10724102.8T patent/DK2564840T3/en active
- 2010-04-26 PL PL10724102T patent/PL2564840T3/pl unknown
- 2010-04-26 EP EP10724102.8A patent/EP2564840B1/en active Active
- 2010-04-26 ES ES10724102T patent/ES2530729T3/es active Active
- 2010-04-26 SI SI201030867T patent/SI2564840T1/sl unknown
- 2010-04-26 US US13/643,643 patent/US20130115290A1/en not_active Abandoned
- 2010-04-26 PT PT107241028T patent/PT2564840E/pt unknown
-
2013
- 2013-10-03 US US14/044,980 patent/US20140037730A1/en not_active Abandoned
-
2015
- 2015-01-28 HR HRP20150100TT patent/HRP20150100T1/hr unknown
- 2015-02-11 SM SM201500033T patent/SMT201500033B/xx unknown
- 2015-02-13 CY CY20151100152T patent/CY1115996T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP2564840A1 (en) | 2013-03-06 |
US20130115290A1 (en) | 2013-05-09 |
PL2564840T3 (pl) | 2015-05-29 |
SI2564840T1 (sl) | 2015-04-30 |
SMT201500033B (it) | 2015-05-05 |
CY1115996T1 (el) | 2017-01-25 |
EP2564840B1 (en) | 2014-11-26 |
WO2011135107A1 (es) | 2011-11-03 |
ES2530729T3 (es) | 2015-03-05 |
DK2564840T3 (en) | 2015-03-02 |
PT2564840E (pt) | 2015-02-27 |
US20140037730A1 (en) | 2014-02-06 |
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