HRP20131204T1 - Nova upotreba amonij klorida u terapiji potpunog ili djelomiäśnog zatajenja jetre i nekroze - Google Patents
Nova upotreba amonij klorida u terapiji potpunog ili djelomiäśnog zatajenja jetre i nekroze Download PDFInfo
- Publication number
- HRP20131204T1 HRP20131204T1 HRP20131204TT HRP20131204T HRP20131204T1 HR P20131204 T1 HRP20131204 T1 HR P20131204T1 HR P20131204T T HRP20131204T T HR P20131204TT HR P20131204 T HRP20131204 T HR P20131204T HR P20131204 T1 HRP20131204 T1 HR P20131204T1
- Authority
- HR
- Croatia
- Prior art keywords
- ammonium chloride
- necrosis
- therapy
- total
- new use
- Prior art date
Links
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 title claims 13
- 235000019270 ammonium chloride Nutrition 0.000 title claims 7
- 206010019663 Hepatic failure Diseases 0.000 title claims 2
- 231100000835 liver failure Toxicity 0.000 title claims 2
- 208000007903 liver failure Diseases 0.000 title claims 2
- 230000017074 necrotic cell death Effects 0.000 title claims 2
- 206010019692 hepatic necrosis Diseases 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 210000002784 stomach Anatomy 0.000 claims 2
- 206010019799 Hepatitis viral Diseases 0.000 claims 1
- 102000014150 Interferons Human genes 0.000 claims 1
- 108010050904 Interferons Proteins 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000000840 anti-viral effect Effects 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 229940047124 interferons Drugs 0.000 claims 1
- 230000002045 lasting effect Effects 0.000 claims 1
- 231100000832 liver cell necrosis Toxicity 0.000 claims 1
- 239000003094 microcapsule Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 201000001862 viral hepatitis Diseases 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/02—Ammonia; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Claims (3)
1. Amonij klorid za upotrebu kao lijek koji poboljšava ili rješava zatajenja jetre uslijed nekroze jetrene stanice, s različitim stupnjevima, izazvane zbog raznih razloga, u shemi liječenja naznačen time da se amonij klorid primjenjuje u dozi između 2g do 5g dnevno tijekom 3 dana uz interval od 4 dana, u trajanju od 1-6 mjeseci i 3-4 mjeseca za bolesnike s djelomičnom nekrozom.
2. Amonij klorid za upotrebu u skladu s patentnim zahtjevom 1, naznačen time da navedeni lijek NH4Cl je u farmaceutskom obliku koji usporava otpuštanje aktivnog sastojka u gastrointestinalnom lumenu, ili u obliku tablete ili kapsule obložene sa spojevima polimera za zaštitu želuca ili u obliku granula ili mikrokapsula sa spojevima polimera za zaštitu želuca, ili spreman za korištenje suspenzije.
3. Amonij klorid za upotrebu u skladu s bilo kojim od patentnih zahtjeva 1 ili 2, naznačen time, da je navedeni amonijev klorid asociran s interferonima i antivirusno za poboljšano liječenje virusnog hepatitisa.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06386019.1A EP1875918B1 (en) | 2006-07-03 | 2006-07-03 | New use of ammonium chloride for the therapy of total or partial hepatic failure and necrosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20131204T1 true HRP20131204T1 (hr) | 2014-02-28 |
Family
ID=37671075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20131204TT HRP20131204T1 (hr) | 2006-07-03 | 2013-12-17 | Nova upotreba amonij klorida u terapiji potpunog ili djelomiäśnog zatajenja jetre i nekroze |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1875918B1 (hr) |
| CY (1) | CY1114843T1 (hr) |
| DK (1) | DK1875918T3 (hr) |
| ES (1) | ES2440196T3 (hr) |
| HR (1) | HRP20131204T1 (hr) |
| PL (1) | PL1875918T3 (hr) |
| PT (1) | PT1875918E (hr) |
| SI (1) | SI1875918T1 (hr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8840934B2 (en) | 2009-01-02 | 2014-09-23 | Rainbow Pharmaceutical Sa | Uses of ammonium chloride |
| US20110045103A1 (en) * | 2009-08-19 | 2011-02-24 | Abukurah Abdul R | Methods for treating aids |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4346082A (en) * | 1980-01-04 | 1982-08-24 | The Vinoxen Company | Method of employing therapeutic composition comprising ammonium or substituted ammonium compounds for treatment of alcoholism |
| NL8401782A (nl) * | 1984-06-04 | 1986-01-02 | Jan Willem Bins | Therapeutisch preparaat met ammoniumnitraat als werkzame stof. |
| GR1003980B (el) * | 2001-04-20 | 2002-09-03 | Ιωαννου Διαμαντης Κιασσος | Νεα χρηση του χλωριουχου αμμωνιου για τη θεραπεια των ενδοηπατικων χολοστασεων οφειλομενων εις δυσπραγια του ηπατικου κυτταρου |
| GR20020100405A (el) * | 2002-09-12 | 2004-05-24 | Διαμαντης Ιωαννου Κιασσος | Νεα χρηση του nh4 cl για την θεραπεια της ηπατικης ινωσεως νεκρωσεως και εγκεφαλοπαθιας οξειας και χρονιας ηπατικης ανεπαρκειας. νεα χρηση του nh4 cl για την θεραπεια της υπερχολερυθριναιμιας, υπερτρασανεμιας προκιρρωτικων και κιρρωτικων καταστασεων του ηπατος, ως επισης για την προληψη της μετατροπης των ως ανω νοσηματων εις νεοπλασματα του ηπατος. |
-
2006
- 2006-07-03 PL PL06386019T patent/PL1875918T3/pl unknown
- 2006-07-03 PT PT63860191T patent/PT1875918E/pt unknown
- 2006-07-03 DK DK06386019.1T patent/DK1875918T3/da active
- 2006-07-03 SI SI200631715T patent/SI1875918T1/sl unknown
- 2006-07-03 ES ES06386019.1T patent/ES2440196T3/es active Active
- 2006-07-03 EP EP06386019.1A patent/EP1875918B1/en active Active
-
2013
- 2013-12-17 HR HRP20131204TT patent/HRP20131204T1/hr unknown
- 2013-12-18 CY CY20131101139T patent/CY1114843T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2440196T3 (es) | 2014-01-28 |
| EP1875918B1 (en) | 2013-09-18 |
| EP1875918A3 (en) | 2008-11-19 |
| PT1875918E (pt) | 2013-12-26 |
| PL1875918T3 (pl) | 2014-03-31 |
| CY1114843T1 (el) | 2016-12-14 |
| SI1875918T1 (sl) | 2014-03-31 |
| EP1875918A2 (en) | 2008-01-09 |
| DK1875918T3 (da) | 2014-01-13 |
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