HRP20120874T1 - Pripravci za lijeäśenje poremeä†aja gornjeg dišnog trakta i sindroma influence - Google Patents
Pripravci za lijeäśenje poremeä†aja gornjeg dišnog trakta i sindroma influence Download PDFInfo
- Publication number
- HRP20120874T1 HRP20120874T1 HRP20120874AT HRP20120874T HRP20120874T1 HR P20120874 T1 HRP20120874 T1 HR P20120874T1 HR P20120874A T HRP20120874A T HR P20120874AT HR P20120874 T HRP20120874 T HR P20120874T HR P20120874 T1 HRP20120874 T1 HR P20120874T1
- Authority
- HR
- Croatia
- Prior art keywords
- preparations
- extract
- hippophae rhamnoides
- specified
- benzophenanthridine alkaloids
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims 3
- 210000002345 respiratory system Anatomy 0.000 title claims 3
- 208000035475 disorder Diseases 0.000 title 1
- 206010022000 influenza Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
- 239000000284 extract Substances 0.000 claims 13
- 238000002360 preparation method Methods 0.000 claims 10
- 240000000950 Hippophae rhamnoides Species 0.000 claims 8
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims 8
- 229930015421 benzophenanthridine alkaloid Natural products 0.000 claims 6
- 150000008622 benzophenanthridines Chemical class 0.000 claims 6
- 244000133098 Echinacea angustifolia Species 0.000 claims 4
- INVGWHRKADIJHF-UHFFFAOYSA-N Sanguinarin Chemical compound C1=C2OCOC2=CC2=C3[N+](C)=CC4=C(OCO5)C5=CC=C4C3=CC=C21 INVGWHRKADIJHF-UHFFFAOYSA-N 0.000 claims 4
- 235000014134 echinacea Nutrition 0.000 claims 4
- WEEFNMFMNMASJY-UHFFFAOYSA-M 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium;chloride Chemical compound [Cl-].C1=C2OCOC2=CC2=CC=C3C4=CC=C(OC)C(OC)=C4C=[N+](C)C3=C21 WEEFNMFMNMASJY-UHFFFAOYSA-M 0.000 claims 2
- LLEJIEBFSOEYIV-UHFFFAOYSA-N Chelerythrine Natural products C1=C2OCOC2=CC2=CC=C3C4=CC=C(OC)C(OC)=C4C=[N+](C)C3=C21 LLEJIEBFSOEYIV-UHFFFAOYSA-N 0.000 claims 2
- RATMHCJTVBHJSU-UHFFFAOYSA-N Dihydrochelerythrine Natural products C1=C2OCOC2=CC2=C(N(C)C(O)C=3C4=CC=C(C=3OC)OC)C4=CC=C21 RATMHCJTVBHJSU-UHFFFAOYSA-N 0.000 claims 2
- AFSDNFLWKVMVRB-UHFFFAOYSA-N Ellagic acid Chemical class OC1=C(O)C(OC2=O)=C3C4=C2C=C(O)C(O)=C4OC(=O)C3=C1 AFSDNFLWKVMVRB-UHFFFAOYSA-N 0.000 claims 2
- FCEXWTOTHXCQCQ-UHFFFAOYSA-N Ethoxydihydrosanguinarine Natural products C12=CC=C3OCOC3=C2C(OCC)N(C)C(C2=C3)=C1C=CC2=CC1=C3OCO1 FCEXWTOTHXCQCQ-UHFFFAOYSA-N 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 2
- GHKISGDRQRSCII-ZOCIIQOWSA-N chelidonine Chemical compound C1=C2[C@H]3N(C)CC4=C(OCO5)C5=CC=C4[C@H]3[C@@H](O)CC2=CC2=C1OCO2 GHKISGDRQRSCII-ZOCIIQOWSA-N 0.000 claims 2
- 210000000214 mouth Anatomy 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 229940084560 sanguinarine Drugs 0.000 claims 2
- YZRQUTZNTDAYPJ-UHFFFAOYSA-N sanguinarine pseudobase Natural products C1=C2OCOC2=CC2=C3N(C)C(O)C4=C(OCO5)C5=CC=C4C3=CC=C21 YZRQUTZNTDAYPJ-UHFFFAOYSA-N 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 241001233914 Chelidonium majus Species 0.000 claims 1
- 240000007849 Macleaya cordata Species 0.000 claims 1
- 241001455961 Macleaya microcarpa Species 0.000 claims 1
- 244000001385 Sanguinaria canadensis Species 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- GHKISGDRQRSCII-UHFFFAOYSA-N chelidonine Natural products C1=C2C3N(C)CC4=C(OCO5)C5=CC=C4C3C(O)CC2=CC2=C1OCO2 GHKISGDRQRSCII-UHFFFAOYSA-N 0.000 claims 1
- 235000015218 chewing gum Nutrition 0.000 claims 1
- 239000006185 dispersion Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000002324 mouth wash Substances 0.000 claims 1
- 241000712461 unidentified influenza virus Species 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Cosmetics (AREA)
Claims (10)
1. Pripravci naznačeni time da su zasnovani na sljedećim:
a) benzofenantridinni alkoloidi,
b) ekstrakt Hippophae rhamnoides,
c) lipofilni ekstrakt Echinacea angustifolia.
2. Pripravci kako su navedeni u patentnom zahtjevu 1, naznačeni time da su zasnovani na sljedećim:
a) benzofenantridinski alkoloidi odabrani od sljedećih: sanguinarine, helerithrin te kelidonin.
b) ekstrakt Hippophae rhamnoides obogaćen derivatima elagične kiseline,
c) lipofilni ekstrakt Echinacea angustifolia.
3. Pripravci kako su navedeni u patentnim zahtjevima 1 i 2, naznačeni time da su razne komponente prisutne u sljedećim rasponima (masa po jedinici doze):
a) benzofenantridinski alkoloidi: od 1 do 5;
b) ekstrakt Hippophae rhamnoides: od 10 do 100;
c) lipofilni ekstrakt Echinacea angustifolia: od 0.2 do 2.
4. Pripravci kako su navedeni u prethodnim patentnim zahtjevima, naznačeni time da su benzofenantridinski alkoloidi sangvinarin, helerithrin te kelidonin prisutni u slobodnom obliku ili u obliku soli, u čistom obliku ili u obliku ekstrakata Sanguinaria canadensis, Macleaya cordata ili Macleaya microcarpa ili Chelidonium majus.
5. Pripravci kako su navedeni u patentnom zahtjevu 4, naznačeni time da su benzofenantridinski alkoloidi prisutni u obliku soli lutenske kiseline.
6. Pripravci kako su navedeni u patentnim zahtjevima 1-5, naznačeni time da je ekstrakt Hippophae rhamnoides prisutan kao ekstrakt Hippophae rhamnoides dobiven ekstrakcijom dijelova obogaćenih derivativima elagične kiseline.
7. Pripravci kako su navedeni u patentnom zahtjevu 6, naznačeni time da je ekstrakt Hippophae rhamnoides prisutan kao ekstrakt Hippophae rhamnoides sa sadržajem 90 % elagitinina.
8. Pripravci kako su navedeni u patentnim zahtjevima 1 do 7, naznačeni time da su u obliku tableta koje se polako otapaju u oralnoj šupljini ili guma za žvakanje koje polako oslobađaju aktivne tvari, vode za usta, gelova za disperziju u oralnoj šupljini i slično.
9. Pripravci naznačeni time da su zasnovani na sljedećim:
a) benzofenantridinni alkoloidi,
b) ekstrakt Hippophae rhamnoides,
c) lipofilni ekstrakt Echinacea angustifolia
za upotrebu u liječenju bakterijskih i virusnih poremećaja gornjeg respiratornog trakta.
10. Pripravci prema patentnom zahtjevu 9, naznačeni time da bakterijski i virusni poremećaji gornjeg respiratornog trakta potječu od stanja uzrokovanih virusima influence.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI20081029 ITMI20081029A1 (it) | 2008-06-05 | 2008-06-05 | Composizioni per il trattamento delle affezioni delle prime vie respiratorie e delle sindromi influenzali |
| EP08425420A EP2133089A1 (en) | 2008-06-12 | 2008-06-12 | Compositions for the treatment of disorders of the upper respiratory tract and influenza syndromes |
| PCT/EP2009/003673 WO2009146807A1 (en) | 2008-06-05 | 2009-05-25 | Compositions for the treatment of disorders of the upper respiratory tract and influenza syndroms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20120874T1 true HRP20120874T1 (hr) | 2012-11-30 |
Family
ID=40872454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20120874AT HRP20120874T1 (hr) | 2008-06-05 | 2012-10-30 | Pripravci za lijeäśenje poremeä†aja gornjeg dišnog trakta i sindroma influence |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9101604B2 (hr) |
| EP (1) | EP2285393B1 (hr) |
| JP (2) | JP5992171B2 (hr) |
| KR (1) | KR20110027671A (hr) |
| CN (1) | CN102056614A (hr) |
| AU (1) | AU2009254262B2 (hr) |
| CA (1) | CA2726872C (hr) |
| DK (1) | DK2285393T3 (hr) |
| ES (1) | ES2393239T3 (hr) |
| HR (1) | HRP20120874T1 (hr) |
| IL (1) | IL209714A (hr) |
| PL (1) | PL2285393T3 (hr) |
| PT (1) | PT2285393E (hr) |
| RU (1) | RU2518738C2 (hr) |
| SI (1) | SI2285393T1 (hr) |
| WO (1) | WO2009146807A1 (hr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011082835A1 (en) * | 2010-01-11 | 2011-07-14 | Vitro-Bio Sarl | New synergistic compositions for the treatment of topical viral infections |
| IT1402018B1 (it) * | 2010-10-11 | 2013-08-28 | Indena Spa | Formulazioni per il trattamento delle affezioni delle prime vie respiratorie. |
| AU2013244472B9 (en) * | 2012-04-03 | 2015-02-19 | The Shizuoka Chamber Of Commerce And Industry | Composition for improving resistance to environmental stress of plant and method for improving resistance to environmental stress of plant |
| JP6320842B2 (ja) * | 2014-05-15 | 2018-05-09 | 株式会社シオンテック | 抗菌性繊維の製造方法及び抗菌性繊維 |
| CN114984010A (zh) * | 2019-08-31 | 2022-09-02 | 广州自远生物科技有限公司 | 异喹啉类化合物制备抗猪呼吸与繁殖综合征病毒产品中的用途 |
| JP7104926B1 (ja) * | 2021-08-03 | 2022-07-22 | 宇航人ジャパン株式会社 | ヘルパーｔ細胞増加剤およびヘルパーｔ細胞増加用の食品組成物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4818533A (en) * | 1985-07-09 | 1989-04-04 | Vipont Pharmaceutical, Inc. | Production of high purity alkaloids |
| RU2098111C1 (ru) | 1994-03-30 | 1997-12-10 | Научно-производственное объединение "Всероссийский научно-исследовательский институт лекарственных и ароматических растений" | Способ получения противовирусного препарата "гипорамин" |
| US20020132021A1 (en) * | 1997-04-30 | 2002-09-19 | Ilya Raskin | Elicited plant products |
| JP2000109428A (ja) * | 1998-10-05 | 2000-04-18 | Taisho Pharmaceut Co Ltd | 咽頭粘膜用組成物 |
| IL152827A0 (en) * | 2000-05-18 | 2003-06-24 | Herbal composition useful for treatment of oral cavity and a method for the local delivery thereof | |
| ITMI20021691A1 (it) * | 2002-07-30 | 2004-01-30 | Indena Spa | Estratti di echinacea angustifolia |
| RU2311192C2 (ru) * | 2003-03-31 | 2007-11-27 | Каунсил Оф Сайентифик Энд Индастриал Рисерч | Способ получения антибактериальной и антиоксидантной фракции из семян облепихи (hippophae rhamnoides l.) |
| US20050031718A1 (en) * | 2003-04-10 | 2005-02-10 | Pharmanex, Llc | Sea Buckthorn compositions and associated methods |
| ITMI20042414A1 (it) * | 2004-12-17 | 2005-03-17 | Indena Spa | Formulazione per il trattamento di affezioni delle prime vie respiratorie |
| US7491414B2 (en) | 2005-10-12 | 2009-02-17 | Gaia Herbs, Inc. | Anti-inflammatory substances extracted from Echinacea |
-
2009
- 2009-05-25 PT PT09757190T patent/PT2285393E/pt unknown
- 2009-05-25 PL PL09757190T patent/PL2285393T3/pl unknown
- 2009-05-25 CN CN2009801209083A patent/CN102056614A/zh active Pending
- 2009-05-25 AU AU2009254262A patent/AU2009254262B2/en not_active Ceased
- 2009-05-25 US US12/996,159 patent/US9101604B2/en not_active Expired - Fee Related
- 2009-05-25 CA CA2726872A patent/CA2726872C/en active Active
- 2009-05-25 KR KR1020107027256A patent/KR20110027671A/ko active Search and Examination
- 2009-05-25 JP JP2011512001A patent/JP5992171B2/ja not_active Expired - Fee Related
- 2009-05-25 RU RU2010153660/15A patent/RU2518738C2/ru active
- 2009-05-25 SI SI200930377T patent/SI2285393T1/sl unknown
- 2009-05-25 WO PCT/EP2009/003673 patent/WO2009146807A1/en active Application Filing
- 2009-05-25 ES ES09757190T patent/ES2393239T3/es active Active
- 2009-05-25 DK DK09757190.5T patent/DK2285393T3/da active
- 2009-05-25 EP EP09757190A patent/EP2285393B1/en active Active
-
2010
- 2010-12-02 IL IL209714A patent/IL209714A/en active IP Right Grant
-
2012
- 2012-10-30 HR HRP20120874AT patent/HRP20120874T1/hr unknown
-
2016
- 2016-05-24 JP JP2016103317A patent/JP2016147914A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2726872C (en) | 2017-05-02 |
| RU2518738C2 (ru) | 2014-06-10 |
| AU2009254262A1 (en) | 2009-12-10 |
| JP2011521982A (ja) | 2011-07-28 |
| KR20110027671A (ko) | 2011-03-16 |
| US20110135769A1 (en) | 2011-06-09 |
| EP2285393B1 (en) | 2012-08-15 |
| CN102056614A (zh) | 2011-05-11 |
| AU2009254262B2 (en) | 2014-02-13 |
| PT2285393E (pt) | 2012-11-29 |
| WO2009146807A8 (en) | 2010-02-04 |
| PL2285393T3 (pl) | 2013-01-31 |
| IL209714A0 (en) | 2011-02-28 |
| DK2285393T3 (da) | 2012-10-22 |
| IL209714A (en) | 2014-02-27 |
| JP2016147914A (ja) | 2016-08-18 |
| JP5992171B2 (ja) | 2016-09-14 |
| WO2009146807A1 (en) | 2009-12-10 |
| ES2393239T3 (es) | 2012-12-19 |
| US9101604B2 (en) | 2015-08-11 |
| EP2285393A1 (en) | 2011-02-23 |
| SI2285393T1 (sl) | 2012-12-31 |
| RU2010153660A (ru) | 2012-07-20 |
| CA2726872A1 (en) | 2009-12-10 |
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