HRP20110954T1 - Proizvod koji sadrži nikotin - Google Patents
Proizvod koji sadrži nikotin Download PDFInfo
- Publication number
- HRP20110954T1 HRP20110954T1 HR20110954T HRP20110954T HRP20110954T1 HR P20110954 T1 HRP20110954 T1 HR P20110954T1 HR 20110954 T HR20110954 T HR 20110954T HR P20110954 T HRP20110954 T HR P20110954T HR P20110954 T1 HRP20110954 T1 HR P20110954T1
- Authority
- HR
- Croatia
- Prior art keywords
- nicotine
- product containing
- pharmaceutically acceptable
- amberlite
- manufacturing
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title claims abstract 24
- 229960002715 nicotine Drugs 0.000 title claims abstract 22
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title claims abstract 22
- 238000004519 manufacturing process Methods 0.000 claims abstract 8
- 239000000758 substrate Substances 0.000 claims abstract 7
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims abstract 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims abstract 6
- 150000001767 cationic compounds Chemical class 0.000 claims abstract 6
- 229910001411 inorganic cation Inorganic materials 0.000 claims abstract 6
- 150000003839 salts Chemical class 0.000 claims abstract 6
- 238000000034 method Methods 0.000 claims abstract 5
- 239000002904 solvent Substances 0.000 claims abstract 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract 4
- 239000000203 mixture Substances 0.000 claims abstract 3
- 239000011780 sodium chloride Substances 0.000 claims abstract 2
- 229920001429 chelating resin Polymers 0.000 claims 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- 239000000825 pharmaceutical preparation Substances 0.000 claims 3
- 229940127557 pharmaceutical product Drugs 0.000 claims 3
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims 2
- 239000000920 calcium hydroxide Substances 0.000 claims 2
- 235000011116 calcium hydroxide Nutrition 0.000 claims 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims 2
- 239000003729 cation exchange resin Substances 0.000 claims 2
- 229920000307 polymer substrate Polymers 0.000 claims 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims 1
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical group OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims 1
- 229960004853 betadex Drugs 0.000 claims 1
- 229940023913 cation exchange resins Drugs 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000011575 calcium Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08022123A EP2198865B1 (en) | 2008-12-19 | 2008-12-19 | Nicotine-containing product |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20110954T1 true HRP20110954T1 (hr) | 2012-01-31 |
Family
ID=40602533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20110954T HRP20110954T1 (hr) | 2008-12-19 | 2011-12-19 | Proizvod koji sadrži nikotin |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9585967B2 (es) |
| EP (2) | EP2392331A1 (es) |
| AR (1) | AR074770A1 (es) |
| AT (1) | ATE533487T1 (es) |
| AU (1) | AU2009328589B2 (es) |
| CA (1) | CA2734403C (es) |
| DK (1) | DK2198865T3 (es) |
| ES (1) | ES2377673T3 (es) |
| HR (1) | HRP20110954T1 (es) |
| MX (1) | MX2011003942A (es) |
| NZ (1) | NZ591209A (es) |
| PL (1) | PL2198865T3 (es) |
| PT (1) | PT2198865E (es) |
| SI (1) | SI2198865T1 (es) |
| UY (1) | UY32337A (es) |
| WO (1) | WO2010069507A1 (es) |
| ZA (1) | ZA201101124B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11911375B2 (en) * | 2020-11-16 | 2024-02-27 | Fertin Pharma A/S | Solid oral nicotine formulation |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3901248A (en) | 1970-07-22 | 1975-08-26 | Leo Ab | Chewable smoking substitute composition |
| GB1332503A (en) * | 1970-10-15 | 1973-10-03 | British American Tobacco Co | Smoking compositions |
| US3845217A (en) * | 1972-11-16 | 1974-10-29 | Helsingborg L Ab | Buffered smoking substitute compositions |
| IT1104351B (it) * | 1978-06-14 | 1985-10-21 | Muzzarelli Riccardo | Il complesso glucano chitosano il metodo della sua produzione a partire da muffe funghi e lieviti e i suoi usi |
| GB9310412D0 (en) | 1993-05-20 | 1993-07-07 | Danbiosyst Uk | Nasal nicotine system |
| GB2385288A (en) | 2002-01-18 | 2003-08-20 | Advanced Phytonics Ltd | Preparing a resinate. |
| US6586449B1 (en) | 2002-05-28 | 2003-07-01 | Cambrex Charles City, Inc. | Nicotine-containing, controlled release composition and method |
| US20050123502A1 (en) * | 2003-10-07 | 2005-06-09 | Chan Shing Y. | Nicotine containing oral compositions |
| US8741935B2 (en) | 2003-12-02 | 2014-06-03 | Fertin Pharma A/S | Nicotine delivery product and method for producing it |
| US20070269492A1 (en) * | 2006-05-16 | 2007-11-22 | Per Steen | New product and use and manufacture thereof |
| US20070269386A1 (en) * | 2006-05-16 | 2007-11-22 | Per Steen | New product and use and manufacture thereof |
| PT2177213E (pt) * | 2008-09-17 | 2013-02-21 | Siegfried Ltd | Granulado contendo nicotina |
-
2008
- 2008-12-19 AT AT08022123T patent/ATE533487T1/de active
- 2008-12-19 EP EP11007015A patent/EP2392331A1/en not_active Withdrawn
- 2008-12-19 SI SI200830503T patent/SI2198865T1/sl unknown
- 2008-12-19 PT PT08022123T patent/PT2198865E/pt unknown
- 2008-12-19 PL PL08022123T patent/PL2198865T3/pl unknown
- 2008-12-19 ES ES08022123T patent/ES2377673T3/es active Active
- 2008-12-19 EP EP08022123A patent/EP2198865B1/en active Active
- 2008-12-19 DK DK08022123.7T patent/DK2198865T3/da active
-
2009
- 2009-12-10 AU AU2009328589A patent/AU2009328589B2/en not_active Ceased
- 2009-12-10 WO PCT/EP2009/008822 patent/WO2010069507A1/en active Application Filing
- 2009-12-10 MX MX2011003942A patent/MX2011003942A/es active IP Right Grant
- 2009-12-10 NZ NZ591209A patent/NZ591209A/xx not_active IP Right Cessation
- 2009-12-10 CA CA2734403A patent/CA2734403C/en active Active
- 2009-12-10 US US13/058,778 patent/US9585967B2/en active Active
- 2009-12-17 AR ARP090104938A patent/AR074770A1/es unknown
- 2009-12-17 UY UY0001032337A patent/UY32337A/es not_active Application Discontinuation
-
2011
- 2011-02-11 ZA ZA2011/01124A patent/ZA201101124B/en unknown
- 2011-12-19 HR HR20110954T patent/HRP20110954T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UY32337A (es) | 2010-07-30 |
| ES2377673T3 (es) | 2012-03-29 |
| CA2734403A1 (en) | 2010-06-24 |
| ATE533487T1 (de) | 2011-12-15 |
| AU2009328589A1 (en) | 2010-06-24 |
| AR074770A1 (es) | 2011-02-09 |
| MX2011003942A (es) | 2011-05-19 |
| WO2010069507A1 (en) | 2010-06-24 |
| PT2198865E (pt) | 2012-02-07 |
| ZA201101124B (en) | 2012-05-30 |
| EP2198865A1 (en) | 2010-06-23 |
| PL2198865T3 (pl) | 2012-04-30 |
| DK2198865T3 (da) | 2012-01-16 |
| CA2734403C (en) | 2013-05-14 |
| EP2198865B1 (en) | 2011-11-16 |
| US20110207782A1 (en) | 2011-08-25 |
| SI2198865T1 (sl) | 2012-02-29 |
| AU2009328589B2 (en) | 2012-12-06 |
| EP2392331A1 (en) | 2011-12-07 |
| US9585967B2 (en) | 2017-03-07 |
| NZ591209A (en) | 2012-11-30 |
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