HRP20090489T1 - Hidantoinski derivati korisni kao inhibitori metaloproteinaza - Google Patents

Hidantoinski derivati korisni kao inhibitori metaloproteinaza Download PDF

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Publication number
HRP20090489T1
HRP20090489T1 HR20090489T HRP20090489T HRP20090489T1 HR P20090489 T1 HRP20090489 T1 HR P20090489T1 HR 20090489 T HR20090489 T HR 20090489T HR P20090489 T HRP20090489 T HR P20090489T HR P20090489 T1 HRP20090489 T1 HR P20090489T1
Authority
HR
Croatia
Prior art keywords
methyl
formula
phenoxy
compound
sulfonyl
Prior art date
Application number
HR20090489T
Other languages
English (en)
Croatian (hr)
Inventor
Waterson David
J. Person David
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HRP20090489T1 publication Critical patent/HRP20090489T1/hr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41661,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR20090489T 2004-12-15 2009-09-15 Hidantoinski derivati korisni kao inhibitori metaloproteinaza HRP20090489T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0427403.1A GB0427403D0 (en) 2004-12-15 2004-12-15 Novel compounds I
PCT/GB2005/004811 WO2006064218A1 (en) 2004-12-15 2005-12-14 Hydantoin derivatives useful as metalloproteinase inhibitors

Publications (1)

Publication Number Publication Date
HRP20090489T1 true HRP20090489T1 (hr) 2009-10-31

Family

ID=34090044

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20090489T HRP20090489T1 (hr) 2004-12-15 2009-09-15 Hidantoinski derivati korisni kao inhibitori metaloproteinaza

Country Status (30)

Country Link
US (1) US8129412B2 (ja)
EP (1) EP1828166B1 (ja)
JP (1) JP5042849B2 (ja)
KR (1) KR20070090921A (ja)
CN (1) CN101080402B (ja)
AR (1) AR051797A1 (ja)
AU (1) AU2005315459B2 (ja)
BR (1) BRPI0519057A2 (ja)
CA (1) CA2589525A1 (ja)
CY (1) CY1109376T1 (ja)
DE (1) DE602005015617D1 (ja)
DK (1) DK1828166T3 (ja)
ES (1) ES2328836T3 (ja)
GB (1) GB0427403D0 (ja)
HK (1) HK1108435A1 (ja)
HR (1) HRP20090489T1 (ja)
IL (1) IL183590A0 (ja)
MX (1) MX2007006744A (ja)
NO (1) NO20073550L (ja)
NZ (1) NZ555684A (ja)
PL (1) PL1828166T3 (ja)
PT (1) PT1828166E (ja)
RS (1) RS51193B (ja)
RU (1) RU2388758C2 (ja)
SA (1) SA05260406B1 (ja)
SI (1) SI1828166T1 (ja)
TW (1) TW200634001A (ja)
UA (1) UA89067C2 (ja)
WO (1) WO2006064218A1 (ja)
ZA (1) ZA200705068B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2381452T3 (es) 2007-10-19 2012-05-28 Boehringer Ingelheim International Gmbh PIPERIDINO-DIHIDROTIENOPIRIMIDINAS sustituidas
WO2009138777A1 (en) * 2008-05-12 2009-11-19 Astrazeneca Ab Process for the preparation of alkoxy-phenoxy-pi peridine
US7759512B2 (en) 2008-07-21 2010-07-20 3M Innovative Properties Company Aqueous methods for making fluorinated sulfonate esters
CN102234287B (zh) 2010-04-26 2015-08-05 上海阳帆医药科技有限公司 硝基咪唑类化合物、其制备方法和用途
US9255074B2 (en) 2010-07-16 2016-02-09 Abbvie Inc. Process for preparing antiviral compounds
KR101774742B1 (ko) 2010-07-16 2017-09-11 애브비 아일랜드 언리미티드 컴퍼니 촉매 반응용 포스핀 리간드
US8975443B2 (en) 2010-07-16 2015-03-10 Abbvie Inc. Phosphine ligands for catalytic reactions
JP5819959B2 (ja) 2010-07-16 2015-11-24 アッヴィ・バハマズ・リミテッド 抗ウイルス性化合物を調製するための方法
HUP1300139A2 (en) 2013-03-06 2014-09-29 Richter Gedeon Nyrt Phenoxypiperidine h3 antagonists
US20160364553A1 (en) * 2015-06-09 2016-12-15 Intel Corporation System, Apparatus And Method For Providing Protected Content In An Internet Of Things (IOT) Network
GB201610056D0 (en) * 2016-06-09 2016-07-27 Galapagos Nv And Laboratoires Servier Les Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders and osteoarthritis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9919776D0 (en) * 1998-08-31 1999-10-27 Zeneca Ltd Compoujnds
EP1187811B1 (en) * 1999-06-04 2007-03-07 AstraZeneca AB Inhibitors of metalloproteinases
RU2283306C2 (ru) 2000-02-21 2006-09-10 Астразенека Аб Пиперидин- и пиперазинзамещенные n-гидроксиформамиды в качестве ингибиторов металлопротеиназ
SE0100902D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0301922D0 (sv) * 2003-06-27 2003-06-27 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
UA89067C2 (ru) 2009-12-25
TW200634001A (en) 2006-10-01
AU2005315459B2 (en) 2009-01-08
NZ555684A (en) 2009-11-27
ZA200705068B (en) 2008-10-29
US20080280950A1 (en) 2008-11-13
JP5042849B2 (ja) 2012-10-03
SA05260406B1 (ar) 2009-02-02
WO2006064218A1 (en) 2006-06-22
MX2007006744A (es) 2007-07-09
RU2007121222A (ru) 2009-01-27
ES2328836T3 (es) 2009-11-18
NO20073550L (no) 2007-09-11
CN101080402A (zh) 2007-11-28
DE602005015617D1 (de) 2009-09-03
EP1828166A1 (en) 2007-09-05
CA2589525A1 (en) 2006-06-22
SI1828166T1 (sl) 2009-12-31
US8129412B2 (en) 2012-03-06
CN101080402B (zh) 2010-12-08
IL183590A0 (en) 2007-09-20
RS51193B (sr) 2010-10-31
JP2008524184A (ja) 2008-07-10
AU2005315459A1 (en) 2006-06-22
GB0427403D0 (en) 2005-01-19
EP1828166B1 (en) 2009-07-22
CY1109376T1 (el) 2014-07-02
DK1828166T3 (da) 2009-10-05
RU2388758C2 (ru) 2010-05-10
BRPI0519057A2 (pt) 2008-12-23
PT1828166E (pt) 2009-09-16
AR051797A1 (es) 2007-02-07
PL1828166T3 (pl) 2009-12-31
KR20070090921A (ko) 2007-09-06
HK1108435A1 (en) 2008-05-09

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