HRP20090151T3 - Derivati indozolona kao inhibitori 11b-hsd1 - Google Patents
Derivati indozolona kao inhibitori 11b-hsd1Info
- Publication number
- HRP20090151T3 HRP20090151T3 HR20090151T HRP20090151T HRP20090151T3 HR P20090151 T3 HRP20090151 T3 HR P20090151T3 HR 20090151 T HR20090151 T HR 20090151T HR P20090151 T HRP20090151 T HR P20090151T HR P20090151 T3 HRP20090151 T3 HR P20090151T3
- Authority
- HR
- Croatia
- Prior art keywords
- alkyl
- fluoro
- alkoxy
- hydrogen
- aryl
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 5
- 229910052736 halogen Inorganic materials 0.000 abstract 5
- 150000002367 halogens Chemical class 0.000 abstract 5
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- -1 aryl-C 1 -C 7 -alkyl Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Spojevi formule (I) ,naznačeni time, da jeR1 vodik, C1-C7-alkil, aril, ili aril-C1-C7-alkil; R2 je aril, aril-C1-C7-alkil, heteroaril, heteroaril-C1-C7-alkil, cikloalkil, cikloalkil-C1-C7-alkil, fluor-C1-C7-alkil, ili C1-C7-alkil, gdje je C1-C7-alkil opcijski supstituiran s 1 do 3 supstituenta izabranih iz skupine koja se sastoji od OH, CN, halogen, C1-C7-alkoksi i C(O)NR8R9;R3 je vodik, halogen, C1-C7-alkil, fluor-C1-C7-alkil, C1-C7-alkoksi ili fluor-C1-C7-alkoksi; R4 je vodik, halogen, C1-C7-alkil, fluor-C1-C7-alkil, C1-C7-alkoksi ili fluor-C1-C7-alkoksi; R5 je vodik, halogen, C1-C7-alkil, fluor-C1-C7-alkil, C1-C7-alkoksi ili fluor-C1-C7-alkoksi; R6 je vodik ili C1-C7-alkil; R7 je aril, heteroaril, fluor-C1-C7-alkil ili C1-C7-alkil gdje je C1-C7-alkil opcijski supstituiran s 1 do 3 supstituenta izabranih iz skupine koja se sastoji od OH, CN, halogen, C1-C7-alkoksi i cikloalkila; R8 i R9 su neovisno jedan od drugog izabrani iz skupine koja se sastoji od vodika i C1-C7-alkila; i njihove farmaceutski prihvatljive soli. Patent sadrži još 30 patentnih zahtjeva.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04104753 | 2004-09-29 | ||
PCT/EP2005/010175 WO2006034804A1 (en) | 2004-09-29 | 2005-09-21 | Indozolone derivatives as 11b-hsd1 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20090151T3 true HRP20090151T3 (hr) | 2009-04-30 |
Family
ID=35447579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20090151T HRP20090151T3 (hr) | 2004-09-29 | 2009-03-16 | Derivati indozolona kao inhibitori 11b-hsd1 |
Country Status (28)
Country | Link |
---|---|
US (1) | US7528158B2 (hr) |
EP (1) | EP1797042B1 (hr) |
JP (1) | JP4682207B2 (hr) |
KR (1) | KR100856164B1 (hr) |
CN (1) | CN101027286B (hr) |
AR (1) | AR050952A1 (hr) |
AT (1) | ATE420076T1 (hr) |
AU (1) | AU2005289107B2 (hr) |
BR (1) | BRPI0515931A (hr) |
CA (1) | CA2581865C (hr) |
DE (1) | DE602005012292D1 (hr) |
DK (1) | DK1797042T3 (hr) |
ES (1) | ES2317305T3 (hr) |
HK (1) | HK1107348A1 (hr) |
HR (1) | HRP20090151T3 (hr) |
IL (1) | IL182212A (hr) |
MX (1) | MX2007003546A (hr) |
MY (1) | MY140841A (hr) |
NO (1) | NO20071617L (hr) |
NZ (1) | NZ553849A (hr) |
PL (1) | PL1797042T3 (hr) |
PT (1) | PT1797042E (hr) |
RU (1) | RU2392272C2 (hr) |
SG (1) | SG148178A1 (hr) |
SI (1) | SI1797042T1 (hr) |
TW (1) | TWI309646B (hr) |
WO (1) | WO2006034804A1 (hr) |
ZA (1) | ZA200702394B (hr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7579360B2 (en) | 2005-06-09 | 2009-08-25 | Bristol-Myers Squibb Company | Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
US7572807B2 (en) | 2005-06-09 | 2009-08-11 | Bristol-Myers Squibb Company | Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors |
US8318941B2 (en) | 2006-07-06 | 2012-11-27 | Bristol-Myers Squibb Company | Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
CA2666193A1 (en) | 2006-08-08 | 2008-02-14 | Sanofi-Aventis | Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, process for preparing them, medicaments comprising these compounds, and their use |
CL2008001839A1 (es) | 2007-06-21 | 2009-01-16 | Incyte Holdings Corp | Compuestos derivados de 2,7-diazaespirociclos, inhibidores de 11-beta hidroxil esteroide deshidrogenasa tipo 1; composicion farmaceutica que comprende a dichos compuestos; utiles para tratar la obesidad, diabetes, intolerancia a la glucosa, diabetes tipo ii, entre otras enfermedades. |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US20090076783A1 (en) * | 2007-09-13 | 2009-03-19 | Tyco Healthcare Retail Services Ag | Digitally optimized fastener assembly and method of making the same |
US8119658B2 (en) | 2007-10-01 | 2012-02-21 | Bristol-Myers Squibb Company | Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
JP2011513409A (ja) * | 2008-03-06 | 2011-04-28 | メルク・シャープ・エンド・ドーム・コーポレイション | 選択的グルココルチコイドレセプターモジュレーターとしてのヘキサヒドロシクロペンチル[f]インダゾールスルホンアミドおよびこれらの誘導体 |
AR072707A1 (es) | 2008-07-09 | 2010-09-15 | Sanofi Aventis | Compuestos heterociclicos, procesos para su preparacion, medicamentos que comprenden estos compuestos y el uso de los mismos |
WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
DK2470552T3 (en) | 2009-08-26 | 2014-02-17 | Sanofi Sa | NOVEL, CRYSTALLINE, heteroaromatic FLUORGLYCOSIDHYDRATER, MEDICINES COVERING THESE COMPOUNDS AND THEIR USE |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
WO2012120050A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8828994B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
WO2012120058A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8895547B2 (en) | 2011-03-08 | 2014-11-25 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120053A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
WO2012120051A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
EP3235813A1 (en) | 2016-04-19 | 2017-10-25 | Cidqo 2012, S.L. | Aza-tetra-cyclo derivatives |
KR101796781B1 (ko) | 2016-05-20 | 2017-11-13 | 한국화학연구원 | 신규한 인다졸 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 암 질환의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL84944A (en) * | 1987-01-19 | 1992-02-16 | Ici Plc | Pharmaceutical compositions containing 1,2-dihydro-3h-indazolone derivatives,some new such compounds and their preparation |
GB9805520D0 (en) | 1998-03-17 | 1998-05-13 | Zeneca Ltd | Chemical compounds |
SE0001899D0 (sv) * | 2000-05-22 | 2000-05-22 | Pharmacia & Upjohn Ab | New compounds |
FR2836914B1 (fr) * | 2002-03-11 | 2008-03-14 | Aventis Pharma Sa | Indazoles substitues, compositions les contenant, procede de fabrication et utilisation |
CA2784937A1 (en) | 2002-05-24 | 2003-12-04 | Millennium Pharmaceuticals, Inc. | Ccr9 inhibitors and methods of use thereof |
JP2007514731A (ja) * | 2003-12-19 | 2007-06-07 | ファイザー インコーポレイテッド | 糖尿病及び肥満症の治療のための11−ベータ−ヒドロキシステロイドデヒドロゲナーゼ1型(11−β−hsd−1)の阻害剤としてのベンゼンスルホニルアミノ−ピリジン−2−イル誘導体及び関連化合物 |
-
2005
- 2005-09-21 RU RU2007116033/04A patent/RU2392272C2/ru not_active IP Right Cessation
- 2005-09-21 ES ES05791184T patent/ES2317305T3/es active Active
- 2005-09-21 PT PT05791184T patent/PT1797042E/pt unknown
- 2005-09-21 CA CA2581865A patent/CA2581865C/en not_active Expired - Fee Related
- 2005-09-21 CN CN2005800322682A patent/CN101027286B/zh not_active Expired - Fee Related
- 2005-09-21 JP JP2007533911A patent/JP4682207B2/ja not_active Expired - Fee Related
- 2005-09-21 DK DK05791184T patent/DK1797042T3/da active
- 2005-09-21 WO PCT/EP2005/010175 patent/WO2006034804A1/en active Application Filing
- 2005-09-21 AU AU2005289107A patent/AU2005289107B2/en not_active Ceased
- 2005-09-21 DE DE602005012292T patent/DE602005012292D1/de active Active
- 2005-09-21 SG SG200808470-9A patent/SG148178A1/en unknown
- 2005-09-21 BR BRPI0515931-8A patent/BRPI0515931A/pt not_active IP Right Cessation
- 2005-09-21 NZ NZ553849A patent/NZ553849A/en not_active IP Right Cessation
- 2005-09-21 KR KR1020077007018A patent/KR100856164B1/ko not_active IP Right Cessation
- 2005-09-21 MX MX2007003546A patent/MX2007003546A/es active IP Right Grant
- 2005-09-21 PL PL05791184T patent/PL1797042T3/pl unknown
- 2005-09-21 SI SI200530605T patent/SI1797042T1/sl unknown
- 2005-09-21 EP EP05791184A patent/EP1797042B1/en active Active
- 2005-09-21 AT AT05791184T patent/ATE420076T1/de active
- 2005-09-26 AR ARP050104014A patent/AR050952A1/es unknown
- 2005-09-26 US US11/235,375 patent/US7528158B2/en not_active Expired - Fee Related
- 2005-09-26 TW TW094133289A patent/TWI309646B/zh not_active IP Right Cessation
- 2005-09-27 MY MYPI20054555A patent/MY140841A/en unknown
-
2007
- 2007-03-22 ZA ZA200702394A patent/ZA200702394B/xx unknown
- 2007-03-26 IL IL182212A patent/IL182212A/en not_active IP Right Cessation
- 2007-03-27 NO NO20071617A patent/NO20071617L/no not_active Application Discontinuation
-
2008
- 2008-01-30 HK HK08101177.5A patent/HK1107348A1/xx not_active IP Right Cessation
-
2009
- 2009-03-16 HR HR20090151T patent/HRP20090151T3/hr unknown
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