HRP20090104T3 - Solid pharmaceutical composition comprising donepezil hydrochloride - Google Patents
Solid pharmaceutical composition comprising donepezil hydrochlorideInfo
- Publication number
- HRP20090104T3 HRP20090104T3 HR20090104T HRP20090104T HRP20090104T3 HR P20090104 T3 HRP20090104 T3 HR P20090104T3 HR 20090104 T HR20090104 T HR 20090104T HR P20090104 T HRP20090104 T HR P20090104T HR P20090104 T3 HRP20090104 T3 HR P20090104T3
- Authority
- HR
- Croatia
- Prior art keywords
- pharmaceutical composition
- solid pharmaceutical
- donepezil hydrochloride
- donepezil
- hydrochloride
- Prior art date
Links
- 229960003135 donepezil hydrochloride Drugs 0.000 title abstract 2
- XWAIAVWHZJNZQQ-UHFFFAOYSA-N donepezil hydrochloride Chemical compound [H+].[Cl-].O=C1C=2C=C(OC)C(OC)=CC=2CC1CC(CC1)CCN1CC1=CC=CC=C1 XWAIAVWHZJNZQQ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Glanulating (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004051055 | 2004-10-19 | ||
| PCT/EP2005/011249 WO2006045512A1 (en) | 2004-10-19 | 2005-10-19 | Solid pharmaceutical composition comprising donepezil hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090104T3 true HRP20090104T3 (en) | 2009-03-31 |
Family
ID=35464350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090104T HRP20090104T3 (en) | 2004-10-19 | 2009-02-19 | Solid pharmaceutical composition comprising donepezil hydrochloride |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US20090130205A9 (es) |
| EP (3) | EP2283811A1 (es) |
| JP (1) | JP2008517022A (es) |
| AT (1) | ATE415148T1 (es) |
| CA (1) | CA2584547C (es) |
| CY (1) | CY1109956T1 (es) |
| DE (1) | DE602005011326D1 (es) |
| DK (1) | DK1811957T3 (es) |
| EA (1) | EA012220B1 (es) |
| ES (1) | ES2317313T3 (es) |
| HR (1) | HRP20090104T3 (es) |
| NO (1) | NO20072494L (es) |
| PL (1) | PL1811957T3 (es) |
| PT (1) | PT1811957E (es) |
| RS (1) | RS51271B (es) |
| SI (1) | SI1811957T1 (es) |
| UA (1) | UA83152C2 (es) |
| WO (1) | WO2006045512A1 (es) |
| ZA (1) | ZA200704023B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0515803D0 (en) * | 2005-07-30 | 2005-09-07 | Pliva Hrvatska D O O | Intermediate compounds |
| DE102005060377A1 (de) * | 2005-12-16 | 2007-06-21 | Ratiopharm Gmbh | Pharmazeutische Zusammensetzung enthaltend Donepezilhydrochlorid, Tablette hieraus und Verfahren zu deren Herstellung |
| EP2037918A2 (en) * | 2006-05-15 | 2009-03-25 | Acadia Pharmaceuticals Inc. | Pharmaceutical formulations of pimavanserin |
| GB0614586D0 (en) * | 2006-07-22 | 2006-08-30 | Pliva Istrazivacki Inst D O O | Pharmaceutical Formulation |
| WO2008092011A2 (en) * | 2007-01-24 | 2008-07-31 | Cook Incorporated | Biofilm-inhibiting medical products |
| GR20070100405A (el) * | 2007-06-26 | 2009-01-20 | Genepharm �.�. | Βελτιωμενες φαρμακοτεχνικες μορφες που περιεχουν αναστολεις της ακετυλοχοληνεστερασης και μεθοδοι παρασκευης αυτων |
| DE102007037932A1 (de) * | 2007-08-11 | 2009-02-12 | Alfred E. Tiefenbacher Gmbh & Co.Kg | Donepezilhydrochlorid in amorpher Form enthaltende Tablette |
| DE102009041839A1 (de) * | 2009-09-18 | 2011-03-24 | Dolorgiet Gmbh & Co. Kg | Donepezil-haltige Tabletten |
| US20100178307A1 (en) * | 2010-01-13 | 2010-07-15 | Jianye Wen | Transdermal anti-dementia active agent formulations and methods for using the same |
| EP2366378A1 (en) | 2010-03-01 | 2011-09-21 | Dexcel Pharma Technologies Ltd. | Sustained-release donepezil formulations |
| DE102010010998A1 (de) * | 2010-03-10 | 2011-09-15 | Stada Arzneimittel Ag | Feste pharmazeutische Zusammensetzung, umfassend Donepezil-Hydrochlorid der kristallinen polymorphen Form I |
| WO2012016708A1 (en) | 2010-08-06 | 2012-02-09 | Ratiopharm Gmbh | Oral dosage form comprising dimebolin and donepezil |
| AU2011334679B2 (en) * | 2010-11-30 | 2016-12-15 | Wista Laboratories Ltd. | Formulations comprising methylthioninium chloride |
| EP2502620A1 (en) | 2011-03-24 | 2012-09-26 | Krka Tovarna Zdravil, D.D., Novo Mesto | Solid pharmaceutical composition comprising donepezil |
| US20150216849A1 (en) | 2014-02-04 | 2015-08-06 | Forest Laboratories Holdings Ltd. | Donepezil compositions and methods of treating alzheimers disease |
| CN114272219B (zh) * | 2021-12-30 | 2023-11-10 | 江苏豪森药业集团有限公司 | 一种盐酸多奈哌齐片及其制备方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8813064D0 (en) * | 1988-06-02 | 1988-07-06 | Euro Celtique Sa | Controlled release dosage forms having defined water content |
| US4956182A (en) * | 1989-03-16 | 1990-09-11 | Bristol-Myers Company | Direct compression cholestyramine tablet and solvent-free coating therefor |
| US5698224A (en) * | 1994-06-27 | 1997-12-16 | Alza Corporation | Tacrine therapy |
| TW513409B (en) * | 1996-06-07 | 2002-12-11 | Eisai Co Ltd | Polymorphs of donepezil hydrochloride |
| SK285312B6 (sk) | 1996-06-07 | 2006-10-05 | Eisai Co., Ltd. | Polymorf (III) donepezil hydrochloridu, spôsob jeho výroby a terapeutický prostriedok s jeho obsahom |
| JPH1053576A (ja) * | 1996-06-07 | 1998-02-24 | Eisai Co Ltd | 塩酸ドネペジルの多形結晶およびその製造法 |
| WO1997046526A1 (en) * | 1996-06-07 | 1997-12-11 | Eisai Co., Ltd. | Stable polymorphs of donepezil (1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine) hydrochloride and process for production |
| CA2279846C (en) * | 1997-02-07 | 2008-06-03 | Princeton University | Engineered protein kinases which can utilize modified nucleotide triphosphate substrates |
| US20030077227A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
| US6066339A (en) * | 1997-10-17 | 2000-05-23 | Elan Corporation, Plc | Oral morphine multiparticulate formulation |
| CN1195862C (zh) * | 1998-02-19 | 2005-04-06 | 札幌啤酒株式会社 | 分离和纯化的包括在蛇麻腺中特异性表达的基因的核酸 |
| WO2000059544A1 (fr) | 1999-03-31 | 2000-10-12 | Eisai Co., Ltd. | Compositions stabilisees contenant des medicaments nootropes |
| US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| JP4107842B2 (ja) * | 2000-03-01 | 2008-06-25 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ポリビニルアルコールを配合した速崩壊性錠剤 |
| US20030022921A1 (en) * | 2001-02-21 | 2003-01-30 | Minutza Leibovici | Stable pharmaceutical formulation comprising torsemide modification II |
| IN192180B (es) * | 2001-09-28 | 2004-03-06 | Ranbaxy Lab | |
| TWI231760B (en) * | 2001-12-20 | 2005-05-01 | Chugai Pharmaceutical Co Ltd | Coated lozenge and manufacturing method thereof |
| SI21223A (sl) * | 2002-06-19 | 2003-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom |
| IL150509A (en) | 2002-07-01 | 2007-07-04 | Joseph Kaspi | Pharmaceutical preparations containing donafazil hydrochloride |
| AU2003280324A1 (en) * | 2002-11-26 | 2004-06-18 | Alk-Abello A/S | Pharmaceutical allergen product |
| AU2003245029A1 (en) * | 2003-04-16 | 2004-11-04 | Hetero Drugs Limited | Novel crystalline forms of donepezil hydrochloride |
| US20040265375A1 (en) | 2003-04-16 | 2004-12-30 | Platteeuw Johannes J. | Orally disintegrating tablets |
| US20040265372A1 (en) * | 2003-06-27 | 2004-12-30 | David Wynn | Soft tablet containing high molecular weight cellulosics |
-
2005
- 2005-10-19 EP EP10176222A patent/EP2283811A1/en not_active Withdrawn
- 2005-10-19 EA EA200700673A patent/EA012220B1/ru not_active IP Right Cessation
- 2005-10-19 PL PL05795965T patent/PL1811957T3/pl unknown
- 2005-10-19 PT PT05795965T patent/PT1811957E/pt unknown
- 2005-10-19 ES ES05795965T patent/ES2317313T3/es active Active
- 2005-10-19 CA CA2584547A patent/CA2584547C/en not_active Expired - Fee Related
- 2005-10-19 AT AT05795965T patent/ATE415148T1/de active
- 2005-10-19 RS RSP-2009/0048A patent/RS51271B/sr unknown
- 2005-10-19 WO PCT/EP2005/011249 patent/WO2006045512A1/en active Application Filing
- 2005-10-19 UA UAA200704303A patent/UA83152C2/ru unknown
- 2005-10-19 US US11/577,414 patent/US20090130205A9/en not_active Abandoned
- 2005-10-19 SI SI200530575T patent/SI1811957T1/sl unknown
- 2005-10-19 EP EP08020395A patent/EP2039349A1/en not_active Withdrawn
- 2005-10-19 JP JP2007537202A patent/JP2008517022A/ja active Pending
- 2005-10-19 DK DK05795965T patent/DK1811957T3/da active
- 2005-10-19 DE DE602005011326T patent/DE602005011326D1/de active Active
- 2005-10-19 EP EP05795965A patent/EP1811957B1/en not_active Revoked
-
2007
- 2007-05-15 NO NO20072494A patent/NO20072494L/no not_active Application Discontinuation
- 2007-05-18 ZA ZA2007/04023A patent/ZA200704023B/en unknown
-
2009
- 2009-02-18 CY CY20091100181T patent/CY1109956T1/el unknown
- 2009-02-19 HR HR20090104T patent/HRP20090104T3/xx unknown
-
2010
- 2010-01-20 US US12/690,498 patent/US20100317694A1/en not_active Abandoned
-
2012
- 2012-01-10 US US13/346,931 patent/US20120283291A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20120283291A1 (en) | 2012-11-08 |
| CA2584547A1 (en) | 2006-05-04 |
| EA012220B1 (ru) | 2009-08-28 |
| NO20072494L (no) | 2007-07-02 |
| WO2006045512A1 (en) | 2006-05-04 |
| RS51271B (sr) | 2010-12-31 |
| ES2317313T3 (es) | 2009-04-16 |
| EP2039349A1 (en) | 2009-03-25 |
| EP1811957A1 (en) | 2007-08-01 |
| CA2584547C (en) | 2014-07-08 |
| US20080063705A1 (en) | 2008-03-13 |
| SI1811957T1 (sl) | 2009-04-30 |
| PT1811957E (pt) | 2009-01-27 |
| CY1109956T1 (el) | 2014-09-10 |
| EA200700673A1 (ru) | 2007-10-26 |
| US20090130205A9 (en) | 2009-05-21 |
| DK1811957T3 (da) | 2009-03-30 |
| EP1811957B1 (en) | 2008-11-26 |
| ATE415148T1 (de) | 2008-12-15 |
| UA83152C2 (ru) | 2008-06-10 |
| JP2008517022A (ja) | 2008-05-22 |
| PL1811957T3 (pl) | 2009-05-29 |
| ZA200704023B (en) | 2008-04-30 |
| EP2283811A1 (en) | 2011-02-16 |
| US20100317694A1 (en) | 2010-12-16 |
| DE602005011326D1 (de) | 2009-01-08 |
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