HRP20080682T3 - Dealkylated derivatives of pyrrolo(2,1-b)benzothiazepines with atypical antipsychotic activity - Google Patents
Dealkylated derivatives of pyrrolo(2,1-b)benzothiazepines with atypical antipsychotic activityInfo
- Publication number
- HRP20080682T3 HRP20080682T3 HR20080682T HRP20080682T HRP20080682T3 HR P20080682 T3 HRP20080682 T3 HR P20080682T3 HR 20080682 T HR20080682 T HR 20080682T HR P20080682 T HRP20080682 T HR P20080682T HR P20080682 T3 HRP20080682 T3 HR P20080682T3
- Authority
- HR
- Croatia
- Prior art keywords
- benzothiazepines
- pyrrolo
- atypical antipsychotic
- antipsychotic activity
- dealkylated
- Prior art date
Links
- 230000000561 anti-psychotic effect Effects 0.000 title 1
- 239000003693 atypical antipsychotic agent Substances 0.000 title 1
- 229940127236 atypical antipsychotics Drugs 0.000 title 1
- 150000007657 benzothiazepines Chemical class 0.000 title 1
- -1 1-piperazinyl Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000222A ITRM20040222A1 (it) | 2004-05-07 | 2004-05-07 | Derivati dealchilati di pirrolo[2,1-b]benzotiazepine ad attivita' antipsicotica atipica. |
| PCT/IT2005/000246 WO2005108403A2 (en) | 2004-05-07 | 2005-04-28 | Dealkylated derivatives of pyrrolo[2,1-b]benzothiazepines with atypical antipsychotic activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20080682T3 true HRP20080682T3 (en) | 2009-02-28 |
Family
ID=35241343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20080682T HRP20080682T3 (en) | 2004-05-07 | 2008-12-29 | Dealkylated derivatives of pyrrolo(2,1-b)benzothiazepines with atypical antipsychotic activity |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7713956B2 (de) |
| EP (1) | EP1745054B1 (de) |
| JP (1) | JP2007536379A (de) |
| KR (1) | KR20070009735A (de) |
| CN (1) | CN100584846C (de) |
| AR (1) | AR049088A1 (de) |
| AT (1) | ATE414708T1 (de) |
| AU (1) | AU2005240868B2 (de) |
| BR (1) | BRPI0510752A (de) |
| CA (1) | CA2562864A1 (de) |
| CY (1) | CY1108800T1 (de) |
| DE (1) | DE602005011121D1 (de) |
| DK (1) | DK1745054T3 (de) |
| ES (1) | ES2318489T3 (de) |
| HK (1) | HK1101169A1 (de) |
| HR (1) | HRP20080682T3 (de) |
| IT (1) | ITRM20040222A1 (de) |
| MX (1) | MXPA06012888A (de) |
| PL (1) | PL1745054T3 (de) |
| PT (1) | PT1745054E (de) |
| RS (1) | RS50970B (de) |
| SI (1) | SI1745054T1 (de) |
| TW (1) | TW200603811A (de) |
| WO (1) | WO2005108403A2 (de) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1301965B1 (it) * | 1998-07-28 | 2000-07-20 | Sigma Tau Ind Farmaceuti | Pirrolo (2,1-b)(1,3) benzotiazepine con attivita' antipsicoticaatipica. |
| IT1317884B1 (it) * | 2000-08-01 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Pirrolo (2,1-b)(1,3)benzotiazepine e loro uso per la preparazione dimedicamenti ad attivita' antipsicotica classica. |
-
2004
- 2004-05-07 IT IT000222A patent/ITRM20040222A1/it unknown
-
2005
- 2005-04-27 TW TW094113143A patent/TW200603811A/zh unknown
- 2005-04-28 KR KR1020067025815A patent/KR20070009735A/ko not_active Application Discontinuation
- 2005-04-28 ES ES05742911T patent/ES2318489T3/es active Active
- 2005-04-28 AU AU2005240868A patent/AU2005240868B2/en not_active Expired - Fee Related
- 2005-04-28 CN CN200580014656A patent/CN100584846C/zh not_active Expired - Fee Related
- 2005-04-28 CA CA002562864A patent/CA2562864A1/en not_active Abandoned
- 2005-04-28 RS RSP-2009/0064A patent/RS50970B/sr unknown
- 2005-04-28 MX MXPA06012888A patent/MXPA06012888A/es active IP Right Grant
- 2005-04-28 PL PL05742911T patent/PL1745054T3/pl unknown
- 2005-04-28 BR BRPI0510752-0A patent/BRPI0510752A/pt not_active IP Right Cessation
- 2005-04-28 JP JP2007512730A patent/JP2007536379A/ja not_active Withdrawn
- 2005-04-28 EP EP05742911A patent/EP1745054B1/de active Active
- 2005-04-28 AT AT05742911T patent/ATE414708T1/de not_active IP Right Cessation
- 2005-04-28 DE DE602005011121T patent/DE602005011121D1/de active Active
- 2005-04-28 US US11/579,806 patent/US7713956B2/en not_active Expired - Fee Related
- 2005-04-28 SI SI200530526T patent/SI1745054T1/sl unknown
- 2005-04-28 PT PT05742911T patent/PT1745054E/pt unknown
- 2005-04-28 DK DK05742911T patent/DK1745054T3/da active
- 2005-04-28 WO PCT/IT2005/000246 patent/WO2005108403A2/en active Application Filing
- 2005-05-05 AR ARP050101818A patent/AR049088A1/es not_active Application Discontinuation
-
2007
- 2007-08-06 HK HK07108523.2A patent/HK1101169A1/xx not_active IP Right Cessation
-
2008
- 2008-12-29 HR HR20080682T patent/HRP20080682T3/xx unknown
-
2009
- 2009-02-18 CY CY20091100174T patent/CY1108800T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN100584846C (zh) | 2010-01-27 |
| SI1745054T1 (sl) | 2009-02-28 |
| MXPA06012888A (es) | 2007-02-15 |
| AU2005240868A1 (en) | 2005-11-17 |
| JP2007536379A (ja) | 2007-12-13 |
| US20070270402A1 (en) | 2007-11-22 |
| EP1745054A2 (de) | 2007-01-24 |
| AR049088A1 (es) | 2006-06-28 |
| HK1101169A1 (en) | 2007-10-12 |
| DE602005011121D1 (de) | 2009-01-02 |
| CN1950381A (zh) | 2007-04-18 |
| WO2005108403A2 (en) | 2005-11-17 |
| US7713956B2 (en) | 2010-05-11 |
| CY1108800T1 (el) | 2012-05-23 |
| RS50970B (sr) | 2010-10-31 |
| WO2005108403A3 (en) | 2005-12-29 |
| PL1745054T3 (pl) | 2009-05-29 |
| ES2318489T3 (es) | 2009-05-01 |
| DK1745054T3 (da) | 2009-02-09 |
| BRPI0510752A (pt) | 2007-11-20 |
| AU2005240868B2 (en) | 2010-10-21 |
| ATE414708T1 (de) | 2008-12-15 |
| EP1745054B1 (de) | 2008-11-19 |
| CA2562864A1 (en) | 2005-11-17 |
| TW200603811A (en) | 2006-02-01 |
| KR20070009735A (ko) | 2007-01-18 |
| ITRM20040222A1 (it) | 2004-08-07 |
| PT1745054E (pt) | 2009-02-09 |
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