HRP20040186B1 - Use of lhrh-antagonists for the improvement of t-cell mediated immunity - Google Patents
Use of lhrh-antagonists for the improvement of t-cell mediated immunityInfo
- Publication number
- HRP20040186B1 HRP20040186B1 HR20040186A HRP20040186A HRP20040186B1 HR P20040186 B1 HRP20040186 B1 HR P20040186B1 HR 20040186 A HR20040186 A HR 20040186A HR P20040186 A HRP20040186 A HR P20040186A HR P20040186 B1 HRP20040186 B1 HR P20040186B1
- Authority
- HR
- Croatia
- Prior art keywords
- lhrh
- antagonists
- improvement
- cell mediated
- mediated immunity
- Prior art date
Links
- 229940124041 Luteinizing hormone releasing hormone (LHRH) antagonist Drugs 0.000 title 1
- 230000024932 T cell mediated immunity Effects 0.000 title 1
- SBNPWPIBESPSIF-MHWMIDJBSA-N cetrorelix Chemical compound C([C@@H](C(=O)N[C@H](CCCNC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@H](C)C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](CC=1C=NC=CC=1)NC(=O)[C@@H](CC=1C=CC(Cl)=CC=1)NC(=O)[C@@H](CC=1C=C2C=CC=CC2=CC=1)NC(C)=O)C1=CC=C(O)C=C1 SBNPWPIBESPSIF-MHWMIDJBSA-N 0.000 abstract 1
- 229960003230 cetrorelix Drugs 0.000 abstract 1
- 108700008462 cetrorelix Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10137174A DE10137174A1 (de) | 2001-07-31 | 2001-07-31 | Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität |
| PCT/EP2002/008459 WO2003011314A2 (en) | 2001-07-31 | 2002-07-30 | Use of lhrh-antagonists for the improvement of t-cell mediated immunity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20040186A2 HRP20040186A2 (en) | 2004-08-31 |
| HRP20040186B1 true HRP20040186B1 (en) | 2007-05-31 |
Family
ID=7693650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20040186A HRP20040186B1 (en) | 2001-07-31 | 2004-02-25 | Use of lhrh-antagonists for the improvement of t-cell mediated immunity |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1414481B1 (de) |
| JP (1) | JP2005500348A (de) |
| KR (1) | KR20040028957A (de) |
| CN (1) | CN1525865A (de) |
| AR (1) | AR034954A1 (de) |
| AT (1) | ATE315400T1 (de) |
| BR (1) | BR0211498A (de) |
| CA (1) | CA2452524A1 (de) |
| DE (2) | DE10137174A1 (de) |
| HR (1) | HRP20040186B1 (de) |
| HU (1) | HUP0401634A2 (de) |
| IL (1) | IL159285A0 (de) |
| MX (1) | MXPA04000870A (de) |
| NO (1) | NO20040350L (de) |
| NZ (1) | NZ531263A (de) |
| PL (1) | PL364492A1 (de) |
| RU (1) | RU2004106545A (de) |
| WO (1) | WO2003011314A2 (de) |
| ZA (1) | ZA200309889B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL147138A0 (en) * | 2001-12-17 | 2002-08-14 | Yeda Res & Dev | Methods of and pharmaceutical compositions for modulating cell adhesion, migration and extravasation |
| EP1891964A1 (de) * | 2006-08-08 | 2008-02-27 | AEterna Zentaris GmbH | Anwendung von Anfangsdosen von LHRH-Analogen und Erhaltungsdosen von LHRH-Antagonisten zur Behandlung von hormonabhängigen Krebsarten und entsprechende Kits |
| JP2010538989A (ja) * | 2007-09-11 | 2010-12-16 | モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト | Ｈｂｖ感染等の治療における治療剤としてのｎｆ−カッパーｂインヒビターｓｎ５０の使用、及び必要に応じたアンギオテンシンｉｉｉの使用 |
| WO2009033725A1 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of human neuropeptide as a therapeutic agent |
| EP2095818A1 (de) * | 2008-02-29 | 2009-09-02 | AEterna Zentaris GmbH | Verwendung von LHRH-Antagonisten in nicht-kastrierenden Dosen |
| EP2379099A1 (de) * | 2009-01-22 | 2011-10-26 | Maatschap Interne Geneeskunde Rijnstate | Verfahren zur prophylaxe oder behandlung von hitzewallungen |
| WO2016030334A2 (en) | 2014-08-26 | 2016-03-03 | Betanien Hospital | Methods, agents and compositions for treatment of inflammatory conditions |
| CN107007814B (zh) * | 2016-11-04 | 2020-03-17 | 中国科学院昆明动物研究所 | 西曲瑞克在制备治疗艾滋病的药物中的应用 |
| CN108066763A (zh) * | 2017-12-21 | 2018-05-25 | 陈敏 | Pcsk9抑制剂在制备治疗t细胞介导的炎症免疫性疾病药中的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2067123A1 (en) * | 1989-09-25 | 1991-03-26 | Esther M. Sternberg | Evaluative means for detecting inflammatory reactivity and for predicting response to stress |
| DE4320201A1 (de) * | 1993-06-18 | 1995-01-12 | Asta Medica Ag | Verwendung von Cetrorelix und weiteren Nona- und Dekapeptiden zur Herstellung eines Arzneimittels zur Bekämpfung von Aids und zur Wachstumsstimulation |
| DE4342091A1 (de) * | 1993-12-09 | 1995-06-14 | Asta Medica Ag | Erzeugnisse zur Anwendung von initial hohen Dosen von Cetrorelix und Herstellung einer Kombinationspackung zur Verwendung bei Therapie von Krankheiten |
| WO1996003138A1 (en) * | 1994-07-22 | 1996-02-08 | The Medical College Of Hampton Roads | Establishment of tonic ovarian estrogen secretion for extended therapeutic regimens |
| AU3361695A (en) * | 1994-08-10 | 1996-03-07 | Dezso Gaal | Novel gnrh analogues with antitumour effects and pharmaceutical compositions thereof |
| AU4459196A (en) * | 1995-01-23 | 1996-08-14 | Takeda Chemical Industries Ltd. | Sustained-release preparation and use |
| US5780435A (en) * | 1995-12-15 | 1998-07-14 | Praecis Pharmaceuticals Incorporated | Methods for treating prostate cancer with LHRH-R antagonists |
| US6054432A (en) * | 1996-09-12 | 2000-04-25 | Asta Medica Aktiengesellschaft | Means for treating prostate hypertrophy and prostate cancer |
| EP1032397A1 (de) * | 1997-11-24 | 2000-09-06 | University Of Florida Research Foundation, Inc. | Testosterone inhibitoren und verwendung zum neuronalschutz |
| US20020071829A1 (en) * | 1999-04-15 | 2002-06-13 | Richard Boyd | Normalization of defective T cell responsiveness through manipulation of thymic regeneration |
| WO2001078780A1 (fr) * | 2000-04-13 | 2001-10-25 | Takeda Chemical Industries, Ltd. | Agents preventifs/remedes pour la maladie d'alzheimer |
| CA2462046A1 (en) * | 2000-10-13 | 2002-04-18 | Monash University | Improvement of graft acceptance through manipulation of thymic regeneration |
| RU2319501C2 (ru) * | 2001-04-30 | 2008-03-20 | Центарис Гмбх | Способ лечения болезни альцгеймера |
| US20030144203A1 (en) * | 2001-12-19 | 2003-07-31 | Voyager Pharmaceutical Corporation | Methods for slowing senescence and treating and preventing diseases associated with senescence |
-
2001
- 2001-07-31 DE DE10137174A patent/DE10137174A1/de not_active Withdrawn
-
2002
- 2002-07-30 MX MXPA04000870A patent/MXPA04000870A/es unknown
- 2002-07-30 KR KR10-2004-7001327A patent/KR20040028957A/ko not_active Application Discontinuation
- 2002-07-30 DE DE60208701T patent/DE60208701T2/de not_active Expired - Fee Related
- 2002-07-30 HU HU0401634A patent/HUP0401634A2/hu unknown
- 2002-07-30 CA CA002452524A patent/CA2452524A1/en not_active Abandoned
- 2002-07-30 NZ NZ531263A patent/NZ531263A/en unknown
- 2002-07-30 RU RU2004106545/15A patent/RU2004106545A/ru not_active Application Discontinuation
- 2002-07-30 JP JP2003516544A patent/JP2005500348A/ja not_active Withdrawn
- 2002-07-30 EP EP02767276A patent/EP1414481B1/de not_active Expired - Lifetime
- 2002-07-30 CN CNA028136993A patent/CN1525865A/zh active Pending
- 2002-07-30 AT AT02767276T patent/ATE315400T1/de not_active IP Right Cessation
- 2002-07-30 PL PL02364492A patent/PL364492A1/xx unknown
- 2002-07-30 BR BR0211498-4A patent/BR0211498A/pt not_active IP Right Cessation
- 2002-07-30 WO PCT/EP2002/008459 patent/WO2003011314A2/en active IP Right Grant
- 2002-07-30 IL IL15928502A patent/IL159285A0/xx unknown
- 2002-07-31 AR ARP020102902A patent/AR034954A1/es unknown
-
2003
- 2003-12-22 ZA ZA200309889A patent/ZA200309889B/en unknown
-
2004
- 2004-01-26 NO NO20040350A patent/NO20040350L/no not_active Application Discontinuation
- 2004-02-25 HR HR20040186A patent/HRP20040186B1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0401634A2 (hu) | 2004-12-28 |
| MXPA04000870A (es) | 2004-06-03 |
| ZA200309889B (en) | 2004-02-19 |
| CN1525865A (zh) | 2004-09-01 |
| PL364492A1 (en) | 2004-12-13 |
| EP1414481B1 (de) | 2006-01-11 |
| IL159285A0 (en) | 2004-06-01 |
| JP2005500348A (ja) | 2005-01-06 |
| AR034954A1 (es) | 2004-03-24 |
| DE10137174A1 (de) | 2003-02-13 |
| WO2003011314A2 (en) | 2003-02-13 |
| EP1414481A2 (de) | 2004-05-06 |
| DE60208701D1 (de) | 2006-04-06 |
| CA2452524A1 (en) | 2003-02-13 |
| WO2003011314A3 (en) | 2003-10-16 |
| NO20040350L (no) | 2004-01-26 |
| RU2004106545A (ru) | 2005-04-10 |
| KR20040028957A (ko) | 2004-04-03 |
| DE60208701T2 (de) | 2006-08-10 |
| ATE315400T1 (de) | 2006-02-15 |
| BR0211498A (pt) | 2004-08-17 |
| NZ531263A (en) | 2005-05-27 |
| HRP20040186A2 (en) | 2004-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| ARAI | Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application | ||
| PNAN | Change of the applicant name, address/residence |
Owner name: ZENTARIS GMBH, DE |
|
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20060710 Year of fee payment: 5 |
|
| B1PR | Patent granted | ||
| PBON | Lapse due to non-payment of renewal fee |
Effective date: 20070731 |