HRP20030387A2 - Use of antiprogestins for prophylaxis and treatment of hormone dependent diseases - Google Patents

Use of antiprogestins for prophylaxis and treatment of hormone dependent diseases

Info

Publication number
HRP20030387A2
HRP20030387A2 HR20030387A HRP20030387A HRP20030387A2 HR P20030387 A2 HRP20030387 A2 HR P20030387A2 HR 20030387 A HR20030387 A HR 20030387A HR P20030387 A HRP20030387 A HR P20030387A HR P20030387 A2 HRP20030387 A2 HR P20030387A2
Authority
HR
Croatia
Prior art keywords
antiprogestins
prophylaxis
treatment
dependent diseases
hormone dependent
Prior art date
Application number
HR20030387A
Other languages
English (en)
Inventor
Hoffmann Jens
Lichtner Rosemarie
Siemeister Gerhard
Schneider Martin
Fuhrmann Ulrike
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of HRP20030387A2 publication Critical patent/HRP20030387A2/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36Antigestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HR20030387A 2000-10-18 2001-10-17 Use of antiprogestins for prophylaxis and treatment of hormone dependent diseases HRP20030387A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24099800P 2000-10-18 2000-10-18
EP00250341 2000-10-18
PCT/EP2001/012005 WO2002032430A1 (en) 2000-10-18 2001-10-17 Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases

Publications (1)

Publication Number Publication Date
HRP20030387A2 true HRP20030387A2 (en) 2005-04-30

Family

ID=26072951

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030387A HRP20030387A2 (en) 2000-10-18 2001-10-17 Use of antiprogestins for prophylaxis and treatment of hormone dependent diseases

Country Status (26)

Country Link
US (1) US7378406B2 (enExample)
EP (1) EP1328276B1 (enExample)
JP (2) JP2004511522A (enExample)
KR (1) KR100632908B1 (enExample)
CN (1) CN1512886A (enExample)
AT (1) ATE310522T1 (enExample)
AU (2) AU1824302A (enExample)
BG (1) BG107743A (enExample)
BR (1) BR0114665A (enExample)
CA (1) CA2423017C (enExample)
CY (1) CY1104981T1 (enExample)
CZ (1) CZ299942B6 (enExample)
DE (1) DE60115274T2 (enExample)
DK (1) DK1328276T3 (enExample)
EE (1) EE05259B1 (enExample)
ES (1) ES2253443T3 (enExample)
HR (1) HRP20030387A2 (enExample)
HU (1) HUP0301460A3 (enExample)
IL (2) IL154975A0 (enExample)
MX (1) MXPA03002954A (enExample)
NO (1) NO20031740L (enExample)
NZ (1) NZ538346A (enExample)
PL (1) PL360151A1 (enExample)
SI (1) SI1328276T1 (enExample)
SK (1) SK287124B6 (enExample)
WO (1) WO2002032430A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY27301A1 (es) * 2001-05-25 2003-02-28 Schering Ag Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata
DE10159217A1 (de) 2001-11-27 2003-06-05 Schering Ag 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
US9517240B2 (en) * 2006-09-26 2016-12-13 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
US20080268041A1 (en) * 2007-04-23 2008-10-30 Jens Hoffmann Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases
JP2010524997A (ja) * 2007-04-23 2010-07-22 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト Brca単独での、又は抗エストロゲン薬を伴った組み合わせ物としての使用のためのプロゲステロン受容体拮抗薬
US20080261929A1 (en) * 2007-04-23 2008-10-23 Jens Hoffmann Combination of progesterone-receptor antagonist together with an aromatase inhibitor for use in brca mediated diseases
TWI477276B (zh) * 2008-04-28 2015-03-21 Repros Therapeutics Inc 抗黃體素給藥方案
TWI539953B (zh) * 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
DE102009034366A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de) 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102010007722A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
DE102010007719A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
CN107260745A (zh) * 2010-03-22 2017-10-20 利普生物药剂公司 用于抗孕酮的非毒性递送的组合物和方法
US10328022B2 (en) 2012-05-31 2019-06-25 Repros Therapeutics Inc. Formulations and methods for vaginal delivery of antiprogestins
HK1211852A1 (en) 2012-11-02 2016-06-03 Repros Therapeutics Inc. Methods and compositions for treating progesterone-dependent conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3733478A1 (de) * 1987-10-01 1989-04-13 Schering Ag Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore
DE19706061A1 (de) 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette

Also Published As

Publication number Publication date
JP2004511522A (ja) 2004-04-15
KR20030044007A (ko) 2003-06-02
WO2002032430A1 (en) 2002-04-25
US7378406B2 (en) 2008-05-27
JP2010077158A (ja) 2010-04-08
EP1328276A1 (en) 2003-07-23
ATE310522T1 (de) 2005-12-15
MXPA03002954A (es) 2003-08-07
PL360151A1 (en) 2004-09-06
DK1328276T3 (da) 2006-04-03
DE60115274T2 (de) 2006-07-27
BG107743A (bg) 2004-01-30
HUP0301460A2 (hu) 2003-10-28
ES2253443T3 (es) 2006-06-01
EE200300155A (et) 2003-08-15
IL154975A0 (en) 2003-10-31
CN1512886A (zh) 2004-07-14
US20040048841A1 (en) 2004-03-11
BR0114665A (pt) 2004-01-13
SI1328276T1 (sl) 2006-04-30
NO20031740L (no) 2003-06-17
NZ538346A (en) 2007-03-30
SK287124B6 (sk) 2009-12-07
KR100632908B1 (ko) 2006-10-13
CA2423017A1 (en) 2002-04-25
AU2002218243B2 (en) 2006-07-13
CA2423017C (en) 2009-01-06
IL154975A (en) 2007-05-15
AU1824302A (en) 2002-04-29
SK4742003A3 (en) 2004-09-08
DE60115274D1 (de) 2005-12-29
CY1104981T1 (el) 2010-03-03
NO20031740D0 (no) 2003-04-15
CZ299942B6 (cs) 2008-12-29
HUP0301460A3 (en) 2010-01-28
EP1328276B1 (en) 2005-11-23
EE05259B1 (et) 2010-02-15

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
PNAN Change of the applicant name, address/residence

Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE

ODBI Application refused