DK1328276T3 - Anvendelse af antiprogestiner til profylakse og behandling af hormonafhængige sygdomme - Google Patents
Anvendelse af antiprogestiner til profylakse og behandling af hormonafhængige sygdommeInfo
- Publication number
- DK1328276T3 DK1328276T3 DK01987668T DK01987668T DK1328276T3 DK 1328276 T3 DK1328276 T3 DK 1328276T3 DK 01987668 T DK01987668 T DK 01987668T DK 01987668 T DK01987668 T DK 01987668T DK 1328276 T3 DK1328276 T3 DK 1328276T3
- Authority
- DK
- Denmark
- Prior art keywords
- antiprogestins
- hormone
- prophylaxis
- treatment
- dependent diseases
- Prior art date
Links
- 230000000708 anti-progestin effect Effects 0.000 title abstract 4
- 239000003418 antiprogestin Substances 0.000 title abstract 4
- 230000001419 dependent effect Effects 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 229940088597 hormone Drugs 0.000 title abstract 2
- 239000005556 hormone Substances 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title 1
- 238000011282 treatment Methods 0.000 title 1
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24099800P | 2000-10-18 | 2000-10-18 | |
| EP00250341 | 2000-10-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1328276T3 true DK1328276T3 (da) | 2006-04-03 |
Family
ID=26072951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01987668T DK1328276T3 (da) | 2000-10-18 | 2001-10-17 | Anvendelse af antiprogestiner til profylakse og behandling af hormonafhængige sygdomme |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7378406B2 (enExample) |
| EP (1) | EP1328276B1 (enExample) |
| JP (2) | JP2004511522A (enExample) |
| KR (1) | KR100632908B1 (enExample) |
| CN (1) | CN1512886A (enExample) |
| AT (1) | ATE310522T1 (enExample) |
| AU (2) | AU2002218243B2 (enExample) |
| BG (1) | BG107743A (enExample) |
| BR (1) | BR0114665A (enExample) |
| CA (1) | CA2423017C (enExample) |
| CY (1) | CY1104981T1 (enExample) |
| CZ (1) | CZ299942B6 (enExample) |
| DE (1) | DE60115274T2 (enExample) |
| DK (1) | DK1328276T3 (enExample) |
| EE (1) | EE05259B1 (enExample) |
| ES (1) | ES2253443T3 (enExample) |
| HR (1) | HRP20030387A2 (enExample) |
| HU (1) | HUP0301460A3 (enExample) |
| IL (2) | IL154975A0 (enExample) |
| MX (1) | MXPA03002954A (enExample) |
| NO (1) | NO20031740L (enExample) |
| NZ (1) | NZ538346A (enExample) |
| PL (1) | PL360151A1 (enExample) |
| SI (1) | SI1328276T1 (enExample) |
| SK (1) | SK287124B6 (enExample) |
| WO (1) | WO2002032430A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY27301A1 (es) * | 2001-05-25 | 2003-02-28 | Schering Ag | Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata |
| DE10159217A1 (de) | 2001-11-27 | 2003-06-05 | Schering Ag | 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate |
| US20040242551A1 (en) * | 2003-05-28 | 2004-12-02 | Schering Ag | Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases |
| US9517240B2 (en) * | 2006-09-26 | 2016-12-13 | The Regents Of The University Of California | Methods and compositions for cancer prevention and treatment |
| US20080261929A1 (en) * | 2007-04-23 | 2008-10-23 | Jens Hoffmann | Combination of progesterone-receptor antagonist together with an aromatase inhibitor for use in brca mediated diseases |
| CA2683809A1 (en) * | 2007-04-23 | 2008-10-30 | Bayer Schering Pharma Aktiengesellschaft | Progesterone-receptor antagonist for use in brca alone or as combination with antiestrogen |
| US20080268041A1 (en) * | 2007-04-23 | 2008-10-30 | Jens Hoffmann | Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases |
| TWI477276B (zh) * | 2008-04-28 | 2015-03-21 | Repros Therapeutics Inc | 抗黃體素給藥方案 |
| TWI539953B (zh) * | 2008-04-28 | 2016-07-01 | 瑞波若斯治療學公司 | 用於治療乳癌之組成物和方法 |
| DE102009034367A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
| DE102009034368A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
| DE102009034362A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
| DE102009034366A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
| DE102009034525A1 (de) | 2009-07-21 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
| DE102009034526A1 (de) | 2009-07-21 | 2011-02-10 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
| DE102010007722A1 (de) | 2010-02-10 | 2011-08-11 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Progesteronrezeptorantagonisten |
| DE102010007719A1 (de) | 2010-02-10 | 2011-08-11 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Progesteronrezeptorantagonisten |
| MX2012010327A (es) * | 2010-03-22 | 2012-11-16 | Repros Therapeutics Inc | Composiciones y metodos para la administracion no toxica de antiprogestinas. |
| CA2872644A1 (en) | 2012-05-31 | 2013-12-05 | Allergan Pharmaceuticals International Limited | Formulations and methods for vaginal delivery of antiprogestins |
| US9545411B2 (en) | 2012-11-02 | 2017-01-17 | Repros Therapeutics Inc. | Methods and compositions for treating progesterone-dependent conditions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3733478A1 (de) * | 1987-10-01 | 1989-04-13 | Schering Ag | Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore |
| DE19706061A1 (de) * | 1997-02-07 | 1998-08-13 | Schering Ag | Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette |
-
2001
- 2001-10-17 CA CA002423017A patent/CA2423017C/en not_active Expired - Fee Related
- 2001-10-17 CZ CZ20031072A patent/CZ299942B6/cs not_active IP Right Cessation
- 2001-10-17 JP JP2002535668A patent/JP2004511522A/ja not_active Ceased
- 2001-10-17 BR BR0114665-3A patent/BR0114665A/pt not_active Application Discontinuation
- 2001-10-17 KR KR1020037005359A patent/KR100632908B1/ko not_active Expired - Fee Related
- 2001-10-17 DK DK01987668T patent/DK1328276T3/da active
- 2001-10-17 EE EEP200300155A patent/EE05259B1/xx not_active IP Right Cessation
- 2001-10-17 HU HU0301460A patent/HUP0301460A3/hu unknown
- 2001-10-17 AT AT01987668T patent/ATE310522T1/de not_active IP Right Cessation
- 2001-10-17 SI SI200130486T patent/SI1328276T1/sl unknown
- 2001-10-17 EP EP01987668A patent/EP1328276B1/en not_active Expired - Lifetime
- 2001-10-17 HR HR20030387A patent/HRP20030387A2/xx not_active Application Discontinuation
- 2001-10-17 IL IL15497501A patent/IL154975A0/xx active IP Right Grant
- 2001-10-17 MX MXPA03002954A patent/MXPA03002954A/es active IP Right Grant
- 2001-10-17 SK SK474-2003A patent/SK287124B6/sk not_active IP Right Cessation
- 2001-10-17 NZ NZ538346A patent/NZ538346A/en unknown
- 2001-10-17 ES ES01987668T patent/ES2253443T3/es not_active Expired - Lifetime
- 2001-10-17 WO PCT/EP2001/012005 patent/WO2002032430A1/en not_active Ceased
- 2001-10-17 US US10/399,320 patent/US7378406B2/en not_active Expired - Fee Related
- 2001-10-17 PL PL36015101A patent/PL360151A1/xx not_active Application Discontinuation
- 2001-10-17 CN CNA018175686A patent/CN1512886A/zh active Pending
- 2001-10-17 AU AU2002218243A patent/AU2002218243B2/en not_active Ceased
- 2001-10-17 AU AU1824302A patent/AU1824302A/xx active Pending
- 2001-10-17 DE DE60115274T patent/DE60115274T2/de not_active Expired - Lifetime
-
2003
- 2003-03-18 IL IL154975A patent/IL154975A/en not_active IP Right Cessation
- 2003-04-15 NO NO20031740A patent/NO20031740L/no not_active Application Discontinuation
- 2003-04-18 BG BG107743A patent/BG107743A/bg unknown
-
2006
- 2006-02-22 CY CY20061100251T patent/CY1104981T1/el unknown
-
2009
- 2009-12-16 JP JP2009284779A patent/JP2010077158A/ja not_active Ceased
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