HRP20010790A2 - New composition for the cure of large intestine polyps - Google Patents
New composition for the cure of large intestine polyps Download PDFInfo
- Publication number
- HRP20010790A2 HRP20010790A2 HR20010790A HRP20010790A HRP20010790A2 HR P20010790 A2 HRP20010790 A2 HR P20010790A2 HR 20010790 A HR20010790 A HR 20010790A HR P20010790 A HRP20010790 A HR P20010790A HR P20010790 A2 HRP20010790 A2 HR P20010790A2
- Authority
- HR
- Croatia
- Prior art keywords
- root
- ground
- pharmaceutical preparation
- plant
- rhizomae
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 3
- 206010051589 Large intestine polyp Diseases 0.000 title 1
- 208000022131 polyp of large intestine Diseases 0.000 title 1
- 108010037462 Cyclooxygenase 2 Proteins 0.000 claims description 13
- 241000196324 Embryophyta Species 0.000 claims description 11
- 235000003373 curcuma longa Nutrition 0.000 claims description 10
- 244000163122 Curcuma domestica Species 0.000 claims description 9
- 235000003392 Curcuma domestica Nutrition 0.000 claims description 9
- 235000013976 turmeric Nutrition 0.000 claims description 9
- 206010028980 Neoplasm Diseases 0.000 claims description 8
- 240000000560 Citrus x paradisi Species 0.000 claims description 6
- 229940124639 Selective inhibitor Drugs 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 6
- 244000276331 Citrus maxima Species 0.000 claims description 5
- 235000001759 Citrus maxima Nutrition 0.000 claims description 5
- 230000004075 alteration Effects 0.000 claims description 4
- 208000014081 polyp of colon Diseases 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims description 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 7
- 239000000654 additive Substances 0.000 claims 2
- 102000010907 Cyclooxygenase 2 Human genes 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 239000001215 curcuma longa l. root Substances 0.000 claims 1
- 208000037062 Polyps Diseases 0.000 description 12
- 102100038280 Prostaglandin G/H synthase 2 Human genes 0.000 description 9
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 description 8
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
- 230000004054 inflammatory process Effects 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 4
- 108090000790 Enzymes Proteins 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 4
- 235000012754 curcumin Nutrition 0.000 description 4
- 229940109262 curcumin Drugs 0.000 description 4
- 239000004148 curcumin Substances 0.000 description 4
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 102100038277 Prostaglandin G/H synthase 1 Human genes 0.000 description 3
- 108050003243 Prostaglandin G/H synthase 1 Proteins 0.000 description 3
- 208000015768 polyposis Diseases 0.000 description 3
- KMTDMTZBNYGUNX-UHFFFAOYSA-N 4-methylbenzyl alcohol Chemical compound CC1=CC=C(CO)C=C1 KMTDMTZBNYGUNX-UHFFFAOYSA-N 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
- 229930003268 Vitamin C Natural products 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 206010003246 arthritis Diseases 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 239000003112 inhibitor Substances 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 235000019154 vitamin C Nutrition 0.000 description 2
- 239000011718 vitamin C Substances 0.000 description 2
- JESIHYIJKKUWIS-UHFFFAOYSA-N 1-(4-Methylphenyl)ethanol Chemical compound CC(O)C1=CC=C(C)C=C1 JESIHYIJKKUWIS-UHFFFAOYSA-N 0.000 description 1
- 208000003200 Adenoma Diseases 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 206010017817 Gastric polyps Diseases 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010021135 Hypovitaminosis Diseases 0.000 description 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 1
- 206010024612 Lipoma Diseases 0.000 description 1
- 208000005890 Neuroma Diseases 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 229930003448 Vitamin K Natural products 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- -1 celebex Chemical compound 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 235000019503 curry powder Nutrition 0.000 description 1
- KPHWPUGNDIVLNH-UHFFFAOYSA-M diclofenac sodium Chemical compound [Na+].[O-]C(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl KPHWPUGNDIVLNH-UHFFFAOYSA-M 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 206010016629 fibroma Diseases 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 229960001680 ibuprofen Drugs 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 208000018937 joint inflammation Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 description 1
- URLKBWYHVLBVBO-UHFFFAOYSA-N p-dimethylbenzene Natural products CC1=CC=C(C)C=C1 URLKBWYHVLBVBO-UHFFFAOYSA-N 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 229940063674 voltaren Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Macromonomer-Based Addition Polymer (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HR20010790A HRP20010790A2 (en) | 2001-10-25 | 2001-10-25 | New composition for the cure of large intestine polyps |
| PCT/HR2002/000039 WO2003035088A1 (en) | 2001-10-25 | 2002-08-30 | Kurkumin composition for the cure of large intestine polyps |
| EP02801970A EP1469868B1 (de) | 2001-10-25 | 2002-08-30 | Kurkumin-zusammensetzung zur heilung von dickdarmpolypen |
| DE60217720T DE60217720T2 (de) | 2001-10-25 | 2002-08-30 | Kurkumin-zusammensetzung zur heilung von dickdarmpolypen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HR20010790A HRP20010790A2 (en) | 2001-10-25 | 2001-10-25 | New composition for the cure of large intestine polyps |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20010790A2 true HRP20010790A2 (en) | 2003-10-31 |
Family
ID=10947378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20010790A HRP20010790A2 (en) | 2001-10-25 | 2001-10-25 | New composition for the cure of large intestine polyps |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1469868B1 (de) |
| DE (1) | DE60217720T2 (de) |
| HR (1) | HRP20010790A2 (de) |
| WO (1) | WO2003035088A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20072315A1 (it) * | 2007-12-11 | 2009-06-12 | Bios Line Spa | Composizioni orali per la prevenzione e il trattamento dei disturbi del colon su base infiammatoria |
| CN103520348B (zh) * | 2013-10-09 | 2015-11-25 | 葛学义 | 治疗痔疮的外用中药药油 |
-
2001
- 2001-10-25 HR HR20010790A patent/HRP20010790A2/hr not_active Application Discontinuation
-
2002
- 2002-08-30 WO PCT/HR2002/000039 patent/WO2003035088A1/en active IP Right Grant
- 2002-08-30 DE DE60217720T patent/DE60217720T2/de not_active Expired - Lifetime
- 2002-08-30 EP EP02801970A patent/EP1469868B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1469868A1 (de) | 2004-10-27 |
| DE60217720T2 (de) | 2007-11-15 |
| EP1469868B1 (de) | 2007-01-17 |
| DE60217720D1 (de) | 2007-03-08 |
| WO2003035088A1 (en) | 2003-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| OBST | Application withdrawn |