HK66191A - Amido substituted naphthalene and intermediates thereof - Google Patents

Amido substituted naphthalene and intermediates thereof

Info

Publication number
HK66191A
HK66191A HK661/91A HK66191A HK66191A HK 66191 A HK66191 A HK 66191A HK 661/91 A HK661/91 A HK 661/91A HK 66191 A HK66191 A HK 66191A HK 66191 A HK66191 A HK 66191A
Authority
HK
Hong Kong
Prior art keywords
intermediates
substituted naphthalene
amido substituted
amido
naphthalene
Prior art date
Application number
HK661/91A
Other languages
English (en)
Inventor
William V Murray
Michael P Wachter
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of HK66191A publication Critical patent/HK66191A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK661/91A 1986-09-26 1991-08-22 Amido substituted naphthalene and intermediates thereof HK66191A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/912,901 US4681894A (en) 1986-09-26 1986-09-26 Hydroxamic acids and esters

Publications (1)

Publication Number Publication Date
HK66191A true HK66191A (en) 1991-08-30

Family

ID=25432659

Family Applications (1)

Application Number Title Priority Date Filing Date
HK661/91A HK66191A (en) 1986-09-26 1991-08-22 Amido substituted naphthalene and intermediates thereof

Country Status (14)

Country Link
US (1) US4681894A (de)
EP (1) EP0261759B1 (de)
JP (1) JPS6383045A (de)
KR (1) KR880003898A (de)
AU (1) AU592434B2 (de)
CA (1) CA1284336C (de)
DE (1) DE3769418D1 (de)
DK (1) DK241987A (de)
ES (1) ES2038176T3 (de)
GR (1) GR3001804T3 (de)
HK (1) HK66191A (de)
PT (1) PT85786B (de)
SG (1) SG61791G (de)
ZA (1) ZA873395B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268384A (en) * 1990-11-21 1993-12-07 Galardy Richard E Inhibition of angiogenesis by synthetic matrix metalloprotease inhibitors
US5183900A (en) * 1990-11-21 1993-02-02 Galardy Richard E Matrix metalloprotease inhibitors
US5239078A (en) * 1990-11-21 1993-08-24 Glycomed Incorporated Matrix metalloprotease inhibitors
US5189178A (en) * 1990-11-21 1993-02-23 Galardy Richard E Matrix metalloprotease inhibitors
US5117054A (en) * 1991-09-26 1992-05-26 Ortho Pharmaceutical Corporation N-hydroxy, N-methyl propanamides
US5594106A (en) * 1993-08-23 1997-01-14 Immunex Corporation Inhibitors of TNF-α secretion
ATE181055T1 (de) * 1994-05-28 1999-06-15 British Biotech Pharm Succinyl hydroxamsäure-, n-formyl-n-hydroxy- aminocarbonsäure- und succinsäureamid-derivate und ihre verwendung als metalloprotease- inhibitoren
US5891916A (en) * 1995-06-21 1999-04-06 Takeda Chemical Industries, Ltd. Aromatic hydroxamix acid compounds, their production and use
IT1283637B1 (it) * 1996-05-14 1998-04-23 Italfarmaco Spa Composti ad attivita' antinfiammatoria ed immunosoppressiva
EP1549598A4 (de) * 2002-06-07 2008-01-23 Cortical Pty Ltd NAPTHALINDERIVATE; DIE DIE ZYTOKIN- ODER BIOLOGISCHE AKTIVITûT DES MIGRATION INHIBITORY FACTOR (MIF) VON MAKROPHAGEN HEMMEN
CA2676946A1 (en) 2009-08-28 2011-02-28 Lucie Peduto Adam12 inhibitors and their use against inflammation-induced fibrosis
WO2017134265A1 (en) 2016-02-05 2017-08-10 Institut Pasteur Use of inhibitors of adam12 as adjuvants in tumor therapies

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE140836C (de) *
DE141253C (de) *
US4218478A (en) * 1979-01-05 1980-08-19 Ruiko Oiwa Trichostatin as an antiprotozoal agent
US4607053A (en) * 1984-05-17 1986-08-19 E. R. Squibb & Sons, Inc. Arylhydroxamates useful as antiallergy agents
US4604407A (en) * 1985-04-04 1986-08-05 E. R. Squibb & Sons, Inc. Hydroxamates
US4605669A (en) * 1985-04-26 1986-08-12 Abbott Laboratories Lipoxygenase inhibiting naphthohydroxamic acids
US4608390A (en) * 1985-04-26 1986-08-26 Abbott Laboratories Lipoxygenase inhibiting compounds
US4623661A (en) * 1985-04-26 1986-11-18 Abbott Laboratories Lipoxygenase inhibiting compounds

Also Published As

Publication number Publication date
EP0261759A2 (de) 1988-03-30
EP0261759B1 (de) 1991-04-17
PT85786B (pt) 1990-08-31
AU592434B2 (en) 1990-01-11
PT85786A (en) 1987-10-01
JPS6383045A (ja) 1988-04-13
GR3001804T3 (en) 1992-11-23
SG61791G (en) 1991-08-23
DK241987A (da) 1988-03-27
KR880003898A (ko) 1988-05-31
CA1284336C (en) 1991-05-21
ZA873395B (en) 1988-12-28
AU7274787A (en) 1988-03-31
DE3769418D1 (de) 1991-05-23
US4681894A (en) 1987-07-21
EP0261759A3 (en) 1988-08-31
DK241987D0 (da) 1987-05-12
ES2038176T3 (es) 1993-07-16

Similar Documents

Publication Publication Date Title
EP0204659A3 (en) Polyepoxydes and their use
ZA873395B (en) Amido substituted naphthalene and intermediates thereof
DE3565257D1 (en) Hydroxyalkylcycloalkylbenzeneacetamides and benzamides
DE3660256D1 (en) Camphor-di-thiolene-complexes and their use
GR860826B (en) Novel benzamide
GB2213820B (en) Intermediates in the preparation of nitro-meta-phenylenediamines
DE3562486D1 (en) Arginyl-3-carboxy-4-hydroxyanilide and their use
DE3563624D1 (en) Novel substituted trifluorooxetane and preparation thereof
GR860825B (en) Novel benzoylureas
EP0162690A3 (en) 2-oxa-spirocyclic-benzeneacetamides and benzamides
ZA858247B (en) Benzoylureas and intermediates
EP0199485A3 (en) Intermediates and process
IE860118L (en) Pyrrolobenzimidazoles and intermediates thereof
IE850337L (en) Benzothiazolopyrimidinones and intermediates thereof
IE851068L (en) Dibenzoxepins and intermediates thereof
IE862508L (en) Heterobicycloalkanes and intermediates
IE872585L (en) Amido-substituted naphthalene and intermediates
ZA866823B (en) Naphthalene anti-psoritic agents
GB2191482B (en) Substituted pyrimidoindoles and diazepinoindoles
IE871086L (en) Thieno-pyrimidines and intermediates
IE851223L (en) Isoxazolidines and related intermediates
IL92781A0 (en) Preparation of 5-acylamino-1,2,4-triazole-3-sulfonamides and intermediates
IE852199L (en) Benzthiazolones, benzoxazolones and related intermediates
IE891219L (en) Bicyclodiones and intermediates
IE840760L (en) Thienopyridoindoles and intermediates therefor