HK40112901A - Irak4降解剂及其制备方法和应用 - Google Patents

Irak4降解剂及其制备方法和应用 Download PDF

Info

Publication number
HK40112901A
HK40112901A HK62024100850.2A HK62024100850A HK40112901A HK 40112901 A HK40112901 A HK 40112901A HK 62024100850 A HK62024100850 A HK 62024100850A HK 40112901 A HK40112901 A HK 40112901A
Authority
HK
Hong Kong
Prior art keywords
alkyl
membered
cycloalkyl
formula
halogen
Prior art date
Application number
HK62024100850.2A
Other languages
English (en)
Inventor
叶正清
冯焱
李世强
Original Assignee
Leadingtac Pharmaceutical (Shaoxing) Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. filed Critical Leadingtac Pharmaceutical (Shaoxing) Co., Ltd.
Publication of HK40112901A publication Critical patent/HK40112901A/zh

Links

HK62024100850.2A 2021-08-23 2022-08-23 Irak4降解剂及其制备方法和应用 HK40112901A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110966608.X 2021-08-23
CN202210558158.5 2022-05-19
CN202210989448.5 2022-08-17

Publications (1)

Publication Number Publication Date
HK40112901A true HK40112901A (zh) 2025-01-28

Family

ID=

Similar Documents

Publication Publication Date Title
EP4393922A1 (en) Irak4 degradation agent, and preparation method therefor and use thereof
AU2021323304B2 (en) Compound for targeting and degrading protein, and preparation method therefor and use thereof
JP7474527B2 (ja) インダゾール誘導体ならびにその調製方法および応用
WO2022266258A1 (en) Compounds and methods for the targeted degradation of irak-4
TW202440597A (zh) 含戊二醯亞胺之pan-kras-突變降解劑化合物及其用途
CN115448923B (zh) 嘧啶并环化合物及其制备方法和应用
US8575336B2 (en) Indazoles
KR20200120713A (ko) 피리미딘-융합고리 화합물 및 그의 제조방법과 용도
CN116262749A (zh) 一类芳杂环取代的化合物及其制备方法和用途
EP4613748A1 (en) Irak4 degradation agent and use thereof
CN116813647B (zh) 一类含氮稠环类sting调节剂类化合物、制备方法和用途
CN102317289A (zh) 作为β分泌酶抑制剂的内酰胺
CN117412964A (zh) 取代的杂环化合物及其应用
CN116715668B (zh) 一类含氮杂环类细胞周期抑制剂化合物、制备方法和用途
AU2013280599A1 (en) Sulfonamide derivatives and methods of use thereof for improving the pharmacokinetics of a drug
CN116354932A (zh) 嘧啶衍生物及其制备方法和用途
HK40112901A (zh) Irak4降解剂及其制备方法和应用
WO2024213044A1 (en) Azacyclo-carbonyl-fused ring derivatives and use thereof
CN121816352A (zh) 包含萘啶或吡啶并吡啶核的化合物作为ptc通读剂
EP3805219A1 (en) Pyrazolopyrimidine derivative, use thereof and pharmaceutical composition
AU2024287949A1 (en) Aromatic compound, pharmaceutical composition containing same, and use thereof
WO2025031294A1 (zh) 一种irak4降解剂及其药物组合物和药学上的应用
EP4725946A1 (en) Irak4 degradation agent and use thereof
WO2026039844A1 (en) Stat6 degraders and uses thereof
HK1156026B (zh) 吡唑並吡啶激酶抑制劑