HK192595A - Recombinant plasmids useable for the expression of heterologous proteins in bacillus - Google Patents
Recombinant plasmids useable for the expression of heterologous proteins in bacillusInfo
- Publication number
- HK192595A HK192595A HK192595A HK192595A HK192595A HK 192595 A HK192595 A HK 192595A HK 192595 A HK192595 A HK 192595A HK 192595 A HK192595 A HK 192595A HK 192595 A HK192595 A HK 192595A
- Authority
- HK
- Hong Kong
- Prior art keywords
- bacillus
- recombinant plasmids
- useable
- expression
- heterologous proteins
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 241000193830 Bacillus <bacterium> Species 0.000 title abstract 3
- 239000013612 plasmid Substances 0.000 title abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 238000010367 cloning Methods 0.000 abstract 2
- 108010081690 Pertussis Toxin Proteins 0.000 abstract 1
- 230000001588 bifunctional effect Effects 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/07—Bacillus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT19551/87A IT1202612B (it) | 1987-03-03 | 1987-03-03 | Plasmidi ricombinanti utili per l'espressione in bacillus di proteine eterologhe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK192595A true HK192595A (en) | 1995-12-29 |
Family
ID=11158981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK192595A HK192595A (en) | 1987-03-03 | 1995-12-21 | Recombinant plasmids useable for the expression of heterologous proteins in bacillus |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0281530B1 (xx) |
| JP (1) | JP2651446B2 (xx) |
| AT (1) | ATE105864T1 (xx) |
| DE (1) | DE3889562T2 (xx) |
| HK (1) | HK192595A (xx) |
| IT (1) | IT1202612B (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5380653A (en) * | 1980-12-31 | 1995-01-10 | The Finnish National Public Health Institute | Expression vectors and methods for intracellular protein production in bascillus |
| IT1226713B (it) * | 1988-08-05 | 1991-02-05 | Eniricerche Spa | Procedimento per la preparazione di interleuchina 1 beta umana ricombinante in forma omogenea. |
| WO1990009444A1 (en) * | 1989-02-10 | 1990-08-23 | Genesit Oy | A method for producing pertussis toxin subunits |
| WO1990009448A1 (en) * | 1989-02-10 | 1990-08-23 | Genesit Oy | Novel expression vectors and methods for intracellular protein production |
| US5786189A (en) * | 1989-11-29 | 1998-07-28 | Smithkline Beecham Biologicals (S.A.) | Vaccine |
| IT1274168B (it) * | 1994-04-15 | 1997-07-15 | Eniricerche Spa | Vettore plasmidico e suo impiego per la produzione di proteine eterologhe |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4595660A (en) * | 1983-03-02 | 1986-06-17 | University Of Delaware | Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis, mutants and substantially stably transformed mutants of Bacillus subtilis, and methods for utilizing the transformed mutants |
| JPH0779698B2 (ja) * | 1985-10-01 | 1995-08-30 | 萬有製薬株式会社 | 安全性の高い多機能クロ−ニングベクタ− |
| CA1340373C (en) * | 1986-01-28 | 1999-02-02 | Rino Rappuoli | Cloning and sequencing of the dna fragment which codes for the five subunits of the pertussis toxin, a hybrid plasmid containing the dna fragment and micro-organisms transformed by the hybrid plasmid and capable of expressing all or some of the subunits of the pertussis toxin |
| ES2044959T3 (es) * | 1986-12-23 | 1994-01-16 | Univ Leland Stanford Junior | Exotoxina de tos ferina modificada. |
-
1987
- 1987-03-03 IT IT19551/87A patent/IT1202612B/it active
-
1988
- 1988-03-01 DE DE3889562T patent/DE3889562T2/de not_active Expired - Fee Related
- 1988-03-01 EP EP88830078A patent/EP0281530B1/en not_active Expired - Lifetime
- 1988-03-01 AT AT88830078T patent/ATE105864T1/de not_active IP Right Cessation
- 1988-03-03 JP JP63050545A patent/JP2651446B2/ja not_active Expired - Lifetime
-
1995
- 1995-12-21 HK HK192595A patent/HK192595A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0281530B1 (en) | 1994-05-18 |
| IT8719551A0 (it) | 1987-03-03 |
| DE3889562T2 (de) | 1994-12-15 |
| JPH01104179A (ja) | 1989-04-21 |
| EP0281530A1 (en) | 1988-09-07 |
| DE3889562D1 (de) | 1994-06-23 |
| ATE105864T1 (de) | 1994-06-15 |
| JP2651446B2 (ja) | 1997-09-10 |
| IT1202612B (it) | 1989-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |