HK16087A - 3-aryloxy-3-phenylpropylamines - Google Patents
3-aryloxy-3-phenylpropylaminesInfo
- Publication number
- HK16087A HK16087A HK160/87A HK16087A HK16087A HK 16087 A HK16087 A HK 16087A HK 160/87 A HK160/87 A HK 160/87A HK 16087 A HK16087 A HK 16087A HK 16087 A HK16087 A HK 16087A
- Authority
- HK
- Hong Kong
- Prior art keywords
- phenylpropylamines
- aryloxy
- enantiomer
- chem
- pharmaceutically
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Luminescent Compositions (AREA)
- Photoreceptors In Electrophotography (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20649880A | 1980-11-14 | 1980-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK16087A true HK16087A (en) | 1987-02-27 |
Family
ID=22766667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK160/87A HK16087A (en) | 1980-11-14 | 1987-02-19 | 3-aryloxy-3-phenylpropylamines |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP0052492B1 (xx) |
| JP (3) | JPS57114555A (xx) |
| KR (1) | KR830007508A (xx) |
| AT (1) | ATE6422T1 (xx) |
| AU (1) | AU540707B2 (xx) |
| CA (1) | CA1181430A (xx) |
| CS (1) | CS227019B2 (xx) |
| CY (1) | CY1350A (xx) |
| DD (1) | DD201139A5 (xx) |
| DE (1) | DE3162445D1 (xx) |
| DK (1) | DK161887C (xx) |
| EG (1) | EG15458A (xx) |
| ES (1) | ES507142A0 (xx) |
| FI (1) | FI77018C (xx) |
| GB (1) | GB2087883A (xx) |
| GR (1) | GR75395B (xx) |
| HK (1) | HK16087A (xx) |
| HU (1) | HU185475B (xx) |
| IE (1) | IE52170B1 (xx) |
| IL (1) | IL64288A (xx) |
| MY (1) | MY8700709A (xx) |
| NZ (1) | NZ198953A (xx) |
| PH (1) | PH17424A (xx) |
| PL (1) | PL233786A1 (xx) |
| PT (1) | PT73982B (xx) |
| RO (1) | RO83309B (xx) |
| SU (1) | SU1068034A3 (xx) |
| ZA (1) | ZA817863B (xx) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4777291A (en) * | 1985-02-27 | 1988-10-11 | Eli Lilly And Company | Racemization process |
| US5112619A (en) * | 1985-11-12 | 1992-05-12 | Eli Lilly And Company | Orally administerable sustained release pharmaceutical formulation |
| US4797286A (en) * | 1985-11-12 | 1989-01-10 | Eli Lilly And Company | Orally administerable sustained release pharmaceutical formulations |
| GB8823405D0 (en) * | 1988-10-05 | 1988-11-09 | Erba Carlo Spa | Aryloxy-arythio-heteraryloxy-heteroarylthio-alkenylene derivatives of amines |
| DK258389D0 (da) * | 1989-05-26 | 1989-05-26 | Ferrosan As | Aryloxyphenylpropylaminer, deres fremstilling og anvendelse |
| ZA921292B (en) * | 1991-02-25 | 1993-08-23 | Lilly Co Eli | Treatment of lower urinary tract disorders. |
| EP0591434A4 (en) * | 1991-06-26 | 1994-09-14 | Sepracor Inc | Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron |
| EP1208838A3 (en) * | 1991-11-15 | 2003-07-09 | Sepracor Inc. | Pure S(+)isomer fluoxetine |
| CA2124445A1 (en) * | 1991-11-26 | 1993-06-10 | James W. Young | Methods and compositions for treating hypertension, angina and other disorders using optically pure (-) amlodipine |
| EP0576766A1 (en) * | 1992-06-29 | 1994-01-05 | Novo Nordisk A/S | Propanolamine derivatives, their preparation and use |
| TW344661B (en) * | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
| US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| US6548082B1 (en) | 1999-03-01 | 2003-04-15 | Sepracor Inc. | Methods for treating apnea and apnea disorders using optically pure R(+) ondansetron |
| WO2000058262A1 (en) * | 1999-03-29 | 2000-10-05 | Eli Lilly And Company | Stereospecific method for preparing tomoxetine and intermediates thereof |
| WO2000061540A1 (en) | 1999-04-09 | 2000-10-19 | Eli Lilly And Company | Methods for preparing 3-aryloxy-3-arylpropylamines and intermediates thereof |
| DE29923134U1 (de) * | 1999-11-16 | 2000-06-29 | Sanol Arznei Schwarz Gmbh | Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen |
| US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
| EP2266590A3 (en) | 2002-02-22 | 2011-04-20 | Shire LLC | Active agent delivery sytems and methods for protecting and administering active agents |
| GB0229583D0 (en) | 2002-12-19 | 2003-01-22 | Cipla Ltd | A process for preparing duloxetine and intermediates for use therein |
| US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
| US8545881B2 (en) | 2004-04-19 | 2013-10-01 | Eurand Pharmaceuticals, Ltd. | Orally disintegrating tablets and methods of manufacture |
| EP1687254A2 (en) * | 2004-06-28 | 2006-08-09 | Teva Pharmaceutical Fine Chemicals S.R.L. | Process for the optical resolution and recycling of tomoxetine |
| US7439399B2 (en) * | 2004-06-28 | 2008-10-21 | Teva Pharmaceutical Fine Chemicals | Processes for the preparation of atomoxetine hydrochloride |
| CA2568629A1 (en) * | 2004-07-22 | 2006-02-23 | Teva Pharmaceutical Fine Chemicals S.R.L. | Polymorphs of atomoxetine hydrochloride |
| US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
| US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| NZ728442A (en) | 2004-10-21 | 2018-05-25 | Adare Pharmaceuticals Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
| EP1889828A1 (en) * | 2005-04-05 | 2008-02-20 | Teva Pharmaceutical Fine Chemicals S.R.L. | Stable atomoxetine hydrochloride, a process for the preparation thereof, and an analytical control of its stability |
| WO2006108120A1 (en) * | 2005-04-05 | 2006-10-12 | Teva Pharmaceutical Fine Chemicals S.R.L. | Stable atomoxetine hydrochloride, a process for the preparation thereof, and an analytical control of its stability |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| US7485754B2 (en) | 2005-07-08 | 2009-02-03 | Apotex Pharmachem Inc. | Efficient method for preparing 3-aryloxy-3-arylpropylamines and their optical stereoisomers |
| CZ2005473A3 (cs) * | 2005-07-21 | 2006-02-15 | Zentiva, A. S | Zpusob výroby hydrochloridu (R)-N-methyl-3-(2-methylfenoxy)-3-fenylpropylaminu (atomoxetinu) |
| EP1798215A1 (en) * | 2005-12-14 | 2007-06-20 | SOLMAG S.p.A. | Polymorph of atomoxetine hydrochloride in crystalline form |
| ITMI20061987A1 (it) * | 2006-10-16 | 2008-04-17 | Archimica Srl | Processo per la sintesi di arilossipropilammine ed eteroarilossipropilammine. |
| WO2008062473A1 (en) * | 2006-10-31 | 2008-05-29 | Cadila Healthcare Limited | Process for preparing atomoxetine hydrochloride |
| CN100430370C (zh) * | 2006-11-03 | 2008-11-05 | 华东理工大学 | 一种丙胺衍生物及其在制备托莫西汀中的应用 |
| WO2009141833A2 (en) * | 2008-04-17 | 2009-11-26 | Ind-Swift Laboratories Limited | An improved process for synthesizing highly pure atomoxetine |
| MX2012006240A (es) | 2009-12-02 | 2012-10-03 | Aptalis Pharma Ltd | Microcapsulas de fexofenadina y composiciones que contienen las mismas. |
| US9326935B2 (en) | 2013-11-08 | 2016-05-03 | Eli Lilly And Company | Atomoxetine solution |
| GR1008531B (el) | 2014-03-21 | 2015-07-13 | Λαμδα Φαρμακευτικα Εργαστηρια Εφαμροσμενης Ερευνας Και Αναπτυξης Α.Ε., | Ποσιμα διαλυματα που περιεχουν υδροχλωρικη ατομοξετινη |
| EP3069715A1 (en) | 2015-03-20 | 2016-09-21 | Salmon Pharma GmbH | Immediate release dosage forms of Atomoxetine |
| CN106916074A (zh) * | 2017-02-14 | 2017-07-04 | 万特制药(海南)有限公司 | 盐酸托莫西汀的制备 |
| CN110294680A (zh) * | 2018-03-22 | 2019-10-01 | 北京深蓝海生物医药科技有限公司 | 一种盐酸阿托莫西汀的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4194009A (en) * | 1974-01-10 | 1980-03-18 | Eli Lilly And Company | Aryloxyphenylpropylamines for obtaining a psychotropic effect |
| US4018895A (en) | 1974-01-10 | 1977-04-19 | Eli Lilly And Company | Aryloxyphenylpropylamines in treating depression |
| JPS5283811A (en) * | 1976-01-01 | 1977-07-13 | Lilly Co Eli | Aryloxy phenyl propylamines and their salts |
| GB1596033A (en) * | 1978-04-25 | 1981-08-19 | Boots Co Ltd | (-)-(2-methoxyphenyl) ethylamine |
| JPS5536403A (en) * | 1978-07-28 | 1980-03-14 | Nippon Iyakuhin Kogyo Kk | Preparation of 1-benzazonine derivative |
| IT1113029B (it) * | 1979-03-01 | 1986-01-20 | Simes | Processo per la separazione dei due isomeri ottici del moprololo e composizioni farmaceutiche dell'antipodo levogiro |
-
1981
- 1981-11-12 ZA ZA817863A patent/ZA817863B/xx unknown
- 1981-11-12 GR GR66518A patent/GR75395B/el unknown
- 1981-11-12 PL PL23378681A patent/PL233786A1/xx unknown
- 1981-11-12 PT PT73982A patent/PT73982B/pt not_active IP Right Cessation
- 1981-11-12 NZ NZ198953A patent/NZ198953A/en unknown
- 1981-11-12 FI FI813589A patent/FI77018C/fi not_active IP Right Cessation
- 1981-11-12 CA CA000389954A patent/CA1181430A/en not_active Expired
- 1981-11-12 AU AU77427/81A patent/AU540707B2/en not_active Ceased
- 1981-11-12 RO RO105785A patent/RO83309B/ro unknown
- 1981-11-13 AT AT81305387T patent/ATE6422T1/de not_active IP Right Cessation
- 1981-11-13 ES ES507142A patent/ES507142A0/es active Granted
- 1981-11-13 CY CY135081A patent/CY1350A/xx unknown
- 1981-11-13 SU SU813355735A patent/SU1068034A3/ru active
- 1981-11-13 DE DE8181305387T patent/DE3162445D1/de not_active Expired
- 1981-11-13 EP EP81305387A patent/EP0052492B1/en not_active Expired
- 1981-11-13 PH PH26491A patent/PH17424A/en unknown
- 1981-11-13 DD DD81234837A patent/DD201139A5/de not_active IP Right Cessation
- 1981-11-13 CS CS818359A patent/CS227019B2/cs unknown
- 1981-11-13 HU HU813411A patent/HU185475B/hu not_active IP Right Cessation
- 1981-11-13 GB GB8134282A patent/GB2087883A/en active Pending
- 1981-11-13 JP JP56182953A patent/JPS57114555A/ja active Granted
- 1981-11-13 DK DK502781A patent/DK161887C/da active
- 1981-11-13 IE IE2661/81A patent/IE52170B1/en not_active IP Right Cessation
- 1981-11-14 KR KR1019810004404A patent/KR830007508A/ko unknown
- 1981-11-14 EG EG662/81A patent/EG15458A/xx active
- 1981-11-15 IL IL64288A patent/IL64288A/xx not_active IP Right Cessation
-
1987
- 1987-02-19 HK HK160/87A patent/HK16087A/xx not_active IP Right Cessation
- 1987-12-30 MY MY709/87A patent/MY8700709A/xx unknown
-
1990
- 1990-06-05 JP JP2147167A patent/JPH037251A/ja active Granted
- 1990-06-05 JP JP2147166A patent/JPH037250A/ja active Granted
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |