HK151295A - Novel quinolone-carboxylic acid derivatives - Google Patents
Novel quinolone-carboxylic acid derivativesInfo
- Publication number
- HK151295A HK151295A HK151295A HK151295A HK151295A HK 151295 A HK151295 A HK 151295A HK 151295 A HK151295 A HK 151295A HK 151295 A HK151295 A HK 151295A HK 151295 A HK151295 A HK 151295A
- Authority
- HK
- Hong Kong
- Prior art keywords
- general formula
- carboxylic acid
- acid derivatives
- compounds
- novel quinolone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12272288 | 1988-05-19 | ||
JP31041888 | 1988-12-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK151295A true HK151295A (en) | 1995-09-29 |
Family
ID=26459793
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK151295A HK151295A (en) | 1988-05-19 | 1995-09-21 | Novel quinolone-carboxylic acid derivatives |
Country Status (9)
Country | Link |
---|---|
US (1) | US5051509A (de) |
EP (1) | EP0342675B1 (de) |
JP (1) | JPH0395177A (de) |
KR (1) | KR940000368B1 (de) |
AT (1) | ATE117685T1 (de) |
CA (1) | CA1340285C (de) |
DE (1) | DE68920773T2 (de) |
ES (1) | ES2070142T3 (de) |
HK (1) | HK151295A (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH089597B2 (ja) * | 1986-01-21 | 1996-01-31 | 杏林製薬株式会社 | 選択毒性に優れた8‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法 |
FR2656611B1 (fr) * | 1990-01-04 | 1992-05-07 | Hoechst France | Nouvelles quinolones, leurs sels, utiles comme agents antimicrobiens, procede de preparation et leur application a titre de medicaments et compositions les renfermant. |
FR2673426B1 (fr) * | 1991-03-01 | 1993-07-16 | Bouchara Sa | Nouvelles quinolones, leur procede de preparation et les compositions en refermant. |
FR2674854B1 (fr) * | 1991-04-04 | 1995-03-03 | Bouchara | Nouvelles quinolones leur procede de preparation et les compositions pharmaceutiques en refermant. |
FR2675144B1 (fr) * | 1991-04-10 | 1995-06-16 | Bouchara Sa | Nouvelles quinolones difluorees - leur procede de preparation et les compositions pharmaceutiques en renfermant. |
KR100228572B1 (ko) * | 1992-01-31 | 1999-11-01 | 이병언 | 퀴놀론카르복실산 유도체 수화물 결정 |
AU4022593A (en) * | 1992-04-28 | 1993-11-29 | Chugai Seiyaku Kabushiki Kaisha | Process for producing quinolonecarboxylic acid derivative |
FR2692577B1 (fr) * | 1992-05-26 | 1996-02-02 | Bouchara Sa | Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant. |
WO1995011902A1 (fr) * | 1993-10-28 | 1995-05-04 | Kaken Pharmaceutical Co., Ltd. | Derive d'acide quinoleine-carboxylique et son sel |
US5686095A (en) * | 1995-10-23 | 1997-11-11 | Price, Jr.; Francis W. | Method of treating canker sores |
US6387928B1 (en) | 1997-09-15 | 2002-05-14 | The Procter & Gamble Co. | Antimicrobial quinolones, their compositions and uses |
MY138335A (en) | 1997-09-15 | 2009-05-29 | Procter & Gamble | Antimicrobial quinolones, their compositions and uses |
DE19751948A1 (de) | 1997-11-24 | 1999-05-27 | Bayer Ag | Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren |
US6608078B2 (en) | 2000-05-08 | 2003-08-19 | Wockhardt Limited | Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment |
US7098219B2 (en) | 2000-08-01 | 2006-08-29 | Wockhart Limited | Inhibitors of cellular efflux pumps of microbes |
US6964966B2 (en) | 2001-04-25 | 2005-11-15 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
US6878713B2 (en) | 2001-04-25 | 2005-04-12 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
US7423153B2 (en) * | 2002-05-10 | 2008-09-09 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of gatifloxacin |
US6664267B1 (en) | 2002-05-28 | 2003-12-16 | Wockhardt Limited | Crystalline fluoroquinolone arginine salt form |
US6900224B2 (en) | 2002-07-31 | 2005-05-31 | The Procter & Gamble Company | Antimicrobial quinolones, their compositions and uses |
US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
ATE366734T1 (de) | 2003-09-04 | 2007-08-15 | Wockhardt Ltd | Benzochinolizin-2-carbonsäureargininsalz- tetrahydrat |
DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
JP4876165B2 (ja) * | 2006-03-28 | 2012-02-15 | ザ プロクター アンド ギャンブル カンパニー | キノロン中間体を調製するための水素化物還元法 |
MX2008012328A (es) | 2006-03-28 | 2008-10-09 | Procter & Gamble | Sales de malato, y polimorfos de acido (3s,5s)-7-[3-amino-5-metil- piperidinil]-1-ciclopropil-1,4-dihidro-8-metoxi-4-oxo-3-quinolinc arboxilico. |
JP2009531418A (ja) | 2006-03-28 | 2009-09-03 | ザ プロクター アンド ギャンブル カンパニー | キノロン中間体調製のためのカップリング方法 |
CN101437823B (zh) | 2006-05-04 | 2014-12-10 | 勃林格殷格翰国际有限公司 | 多晶型 |
PE20110235A1 (es) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | Combinaciones farmaceuticas que comprenden linagliptina y metmorfina |
EP1852108A1 (de) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Zusammensetzungen von DPP-IV-Inhibitoren |
TWI362386B (en) | 2007-03-30 | 2012-04-21 | Daiichi Sankyo Co Ltd | A production method for the qunolon-carboxylic acid derivative |
CN101450938B (zh) * | 2007-12-04 | 2012-11-14 | 中国医学科学院医药生物技术研究所 | 7-(4-肟基-3-氨基-3-烷基-1-哌啶基)喹啉羧酸衍生物及其制备方法 |
AR071175A1 (es) | 2008-04-03 | 2010-06-02 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante |
KR20200118243A (ko) | 2008-08-06 | 2020-10-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
US9457029B2 (en) | 2009-11-27 | 2016-10-04 | Boehringer Ingelheim International Gmbh | Treatment of genotyped diabetic patients with DPP-IV inhibitors such as linagliptin |
BR112012028136A2 (pt) | 2010-05-05 | 2016-08-09 | Boehringer Ingelheim Int | terapia de combinaçao |
KR20130093012A (ko) | 2010-06-24 | 2013-08-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 당뇨병 요법 |
AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
EP2731947B1 (de) | 2011-07-15 | 2019-01-16 | Boehringer Ingelheim International GmbH | Substituiertes dimeres chinazolin derivat, dessen herstellung und verwendung in pharmazeutischen zusammensetzungen zur behandlung von typ i und typ ii diabetes |
CA2849509A1 (en) | 2011-10-12 | 2013-04-18 | Yoseph Yaacobi | Contact lens cleaning systems |
CN102558145B (zh) * | 2011-12-14 | 2014-04-16 | 中国药科大学 | 巴洛沙星的制备方法 |
US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
EP2849755A1 (de) | 2012-05-14 | 2015-03-25 | Boehringer Ingelheim International GmbH | Xanthinderivat als dpp-4-hemmer zur verwendung bei der behandlung von durch podozyten vermittelten erkrankungen und/oder des nephrotischen syndroms |
WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
EP3110449B1 (de) | 2014-02-28 | 2023-06-28 | Boehringer Ingelheim International GmbH | Medizinische verwendung eines dpp-4-inhibitors |
BR112018072401A2 (pt) | 2016-06-10 | 2019-02-19 | Boehringer Ingelheim International Gmbh | combinações de linagliptina e metformina |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4777175A (en) * | 1982-09-09 | 1988-10-11 | Warner-Lambert Company | Antibacterial agents |
JPS62469A (ja) * | 1985-06-27 | 1987-01-06 | Dainippon Pharmaceut Co Ltd | 新規キノロン誘導体、そのエステルおよびその塩 |
JPH089597B2 (ja) * | 1986-01-21 | 1996-01-31 | 杏林製薬株式会社 | 選択毒性に優れた8‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法 |
NO871333L (no) * | 1986-03-31 | 1987-10-01 | Sankyo Co | Kinolin-3-karboksylsyrederivater, fremgangsmaate til fremstilling og anvendelse derav. |
JPS63198664A (ja) * | 1986-03-31 | 1988-08-17 | Sankyo Co Ltd | キノロンカルボン酸誘導体 |
US4771055A (en) * | 1986-07-28 | 1988-09-13 | Warner-Lambert Company | 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids |
US4851418A (en) * | 1987-08-21 | 1989-07-25 | Warner-Lambert Company | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
-
1989
- 1989-05-18 EP EP89108963A patent/EP0342675B1/de not_active Expired - Lifetime
- 1989-05-18 DE DE68920773T patent/DE68920773T2/de not_active Expired - Lifetime
- 1989-05-18 AT AT89108963T patent/ATE117685T1/de not_active IP Right Cessation
- 1989-05-18 CA CA000600074A patent/CA1340285C/en not_active Expired - Lifetime
- 1989-05-18 ES ES89108963T patent/ES2070142T3/es not_active Expired - Lifetime
- 1989-05-18 JP JP1125093A patent/JPH0395177A/ja active Granted
- 1989-05-19 KR KR1019890006754A patent/KR940000368B1/ko not_active IP Right Cessation
- 1989-05-22 US US07/354,962 patent/US5051509A/en not_active Expired - Lifetime
-
1995
- 1995-09-21 HK HK151295A patent/HK151295A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR940000368B1 (ko) | 1994-01-19 |
ES2070142T3 (es) | 1995-06-01 |
DE68920773D1 (de) | 1995-03-09 |
EP0342675A3 (en) | 1990-12-27 |
JPH0395177A (ja) | 1991-04-19 |
JPH0555506B2 (de) | 1993-08-17 |
CA1340285C (en) | 1998-12-22 |
DE68920773T2 (de) | 1995-05-18 |
KR890017243A (ko) | 1989-12-15 |
EP0342675B1 (de) | 1995-01-25 |
ATE117685T1 (de) | 1995-02-15 |
EP0342675A2 (de) | 1989-11-23 |
US5051509A (en) | 1991-09-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK151295A (en) | Novel quinolone-carboxylic acid derivatives | |
ZA888186B (en) | Quinolinecarboxylic acid derivatives | |
AU591640B2 (en) | Quinolonecarboxylic acid derivatives | |
NZ248099A (en) | Use of spiro-oxathiolane quinuclidine derivatives for treating sjoegren syndrome | |
TW264476B (de) | ||
HK1001396A1 (en) | Pyrimidinylpyrazole derivative | |
CA2056662A1 (en) | Naphthoic acid derivative | |
AU4200089A (en) | Substituted beta-diketones | |
CA2221946A1 (en) | Production process of cyclic compound | |
AU7624494A (en) | Imidazolidinone derivative, acid-addition salt thereof, and remedy for senile dementia | |
EP0308319A3 (en) | 4-piperidinecarboxamide derivatives | |
ATE189813T1 (de) | Prostaglandin-i-analoga | |
GR3020288T3 (en) | Cyclopropachromen derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20090517 |