HK1256334A1 - 陣發性心房纖顫的基於tnt的診斷 - Google Patents

陣發性心房纖顫的基於tnt的診斷

Info

Publication number
HK1256334A1
HK1256334A1 HK18115419.1A HK18115419A HK1256334A1 HK 1256334 A1 HK1256334 A1 HK 1256334A1 HK 18115419 A HK18115419 A HK 18115419A HK 1256334 A1 HK1256334 A1 HK 1256334A1
Authority
HK
Hong Kong
Prior art keywords
atrial fibrillation
based diagnosis
paroxysmal atrial
tnt
tnt based
Prior art date
Application number
HK18115419.1A
Other languages
English (en)
Inventor
Dirk Block
Roberto Latini
Serge Masson
Ursula-Henrike Wienhues-Thelen
Christian Zaugg
André Ziegler
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47143752&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1256334(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1256334A1 publication Critical patent/HK1256334A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4737—C-reactive protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4745—Insulin-like growth factor binding protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5412—IL-6
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/326—Arrhythmias, e.g. ventricular fibrillation, tachycardia, atrioventricular block, torsade de pointes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK18115419.1A 2012-11-09 2018-12-03 陣發性心房纖顫的基於tnt的診斷 HK1256334A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12191996 2012-11-09

Publications (1)

Publication Number Publication Date
HK1256334A1 true HK1256334A1 (zh) 2019-09-20

Family

ID=47143752

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16100057.2A HK1212434A1 (zh) 2012-11-09 2016-01-06 陣發性心房纖顫的基於 的診斷
HK18115419.1A HK1256334A1 (zh) 2012-11-09 2018-12-03 陣發性心房纖顫的基於tnt的診斷

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK16100057.2A HK1212434A1 (zh) 2012-11-09 2016-01-06 陣發性心房纖顫的基於 的診斷

Country Status (8)

Country Link
US (3) US20150233946A1 (zh)
EP (1) EP2917736B1 (zh)
JP (2) JP6366594B2 (zh)
CN (2) CN104769436B (zh)
CA (1) CA2886698C (zh)
ES (1) ES2774288T3 (zh)
HK (2) HK1212434A1 (zh)
WO (1) WO2014072500A1 (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201413081D0 (en) * 2014-07-23 2014-09-03 Univ Birmingham Markers for AF
US10231639B2 (en) 2016-04-19 2019-03-19 Roche Diagnostics Operations, Inc. Algorithm of NTproBNP and hand held ECG to detect arrhythmia in an elderly population
KR102149593B1 (ko) * 2016-06-17 2020-08-31 에프. 호프만-라 로슈 아게 심방 세동 재발의 예측을 위한 순환성 안지오포이에틴-2 (Ang-2)
ES2817087T3 (es) * 2016-08-04 2021-04-06 Hoffmann La Roche ESM-1 (endocan) circulante en la evaluación de la fibrilación auricular
KR102356418B1 (ko) 2017-06-13 2022-02-08 에프. 호프만-라 로슈 아게 심방 세동 (af) 의 평가를 위한 지방산 결합 단백질 3
KR102368403B1 (ko) * 2017-12-13 2022-02-25 에프. 호프만-라 로슈 아게 뇌졸중의 예측을 위한 순환하는 안지오포이에틴-2(Ang-2)와 인슐린-유사 성장 인자-결합 단백질 7(IGFBP7)
BR112021002445A2 (pt) * 2018-08-10 2021-05-04 F. Hoffmann-La Roche Ag métodos para prever o risco de acidente vascular cerebral, para aprimorar a precisão da previsão de uma pontuação de risco clínico, para avaliar a eficácia de uma terapia, para identificar um paciente e para monitorar um paciente, usos e kit
WO2020035588A1 (en) * 2018-08-16 2020-02-20 Roche Diagnostics Gmbh Circulating tfpi-2 (tissue factor pathway inhibitor 2) in the assessment of atrial fibrillation and anticoagulation therapy
EP3841381A1 (en) * 2018-08-22 2021-06-30 Roche Diagnostics GmbH Circulating spon-1 (spondin-1) in the assessment of atrial fibrillation
KR20210049829A (ko) * 2018-08-24 2021-05-06 에프. 호프만-라 로슈 아게 심방 세동의 사정에서 및 뇌졸중의 예측을 위한 순환하는 fgfbp-1 (섬유모세포 성장 인자-결합 단백질 1)
CN109871808B (zh) * 2019-02-21 2021-03-02 天津惊帆科技有限公司 房颤模型训练、检测方法和装置
EP3730942A1 (en) * 2019-04-26 2020-10-28 Fundació Hospital Universitari Vall d' Hebron - Institut de Recerca Diagnosis markers for atrial fibrillation
WO2021118796A1 (en) * 2019-12-13 2021-06-17 Ischemia Care Llc Biomarkers for the diagnosis of atrial fibrillation cause of stroke
EP4196796A1 (en) 2020-08-14 2023-06-21 F. Hoffmann-La Roche AG Igfbp7 for the assessment of silent brain infarcts and cognitive decline
US20230366894A1 (en) 2020-09-30 2023-11-16 Roche Diagnostics Operations, Inc. Circulating total-nt-probnp (glycosylated and unglycosylated nt-probnp) and its ratio with nt-probnp (unglycosylated nt-probnp) in the assessment of atrial fibrillation
US20230288436A1 (en) 2021-10-25 2023-09-14 Bionote, Inc. Antibodies binding specifically to nt-probnp and use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
GB9211686D0 (en) 1992-06-03 1992-07-15 Medisinsk Innovation A S Chemical compounds
US7632647B2 (en) 2001-04-13 2009-12-15 Biosite Incorporated Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes
ATE439588T1 (de) 2001-05-04 2009-08-15 Biosite Inc Diagnostische marker für akute herzerkrankungen und verfahren des gebrauchs
AU2003302340B8 (en) 2002-12-24 2008-09-11 Biosite Incorporated Markers for differential diagnosis and methods of use thereof
CA3086149A1 (en) 2006-04-04 2007-10-11 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
EP2318844A1 (en) * 2008-07-14 2011-05-11 Roche Diagnostics GmbH Multimarker panel for diagnosing, monitoring and selecting the therapy for patients with heart failure
EP2331964A1 (en) 2008-08-13 2011-06-15 Roche Diagnostics GmbH D-dimer, troponin, nt-probnp for pulmonary embolism
EP2414543B1 (en) * 2009-04-03 2016-10-12 Decode Genetics EHF Genetic markers for risk management of atrial fibrillation and stroke
ES2627337T3 (es) 2010-08-26 2017-07-27 F. Hoffmann-La Roche Ag Uso de biomarcadores para controlar una medicación en un sujeto que padece insuficiencia cardíaca
BR122021026652B1 (pt) 2011-10-17 2022-08-23 F. Hoffmann-La Roche Ag Método in vitro para diagnosticar fibrilação atrial intermitente, uso de uma troponina cardíaca e dispositivo para diagnosticar fibrilação atrial intermitente

Also Published As

Publication number Publication date
WO2014072500A1 (en) 2014-05-15
CN108120837A (zh) 2018-06-05
CA2886698A1 (en) 2014-05-15
CN108120837B (zh) 2021-06-22
CN104769436B (zh) 2018-01-26
ES2774288T3 (es) 2020-07-20
EP2917736A1 (en) 2015-09-16
JP6366594B2 (ja) 2018-08-01
CN104769436A (zh) 2015-07-08
JP6654668B2 (ja) 2020-02-26
HK1212434A1 (zh) 2016-06-10
JP2016502659A (ja) 2016-01-28
JP2018151411A (ja) 2018-09-27
US20170074892A1 (en) 2017-03-16
EP2917736B1 (en) 2019-12-25
US20150233946A1 (en) 2015-08-20
CA2886698C (en) 2019-02-19
US20230062697A1 (en) 2023-03-02

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