HK1256104A1 - 作為對象的細胞外容量狀態的標誌物的mr-proadm - Google Patents

作為對象的細胞外容量狀態的標誌物的mr-proadm

Info

Publication number
HK1256104A1
HK1256104A1 HK18115179.1A HK18115179A HK1256104A1 HK 1256104 A1 HK1256104 A1 HK 1256104A1 HK 18115179 A HK18115179 A HK 18115179A HK 1256104 A1 HK1256104 A1 HK 1256104A1
Authority
HK
Hong Kong
Prior art keywords
proadm
marker
subject
volume status
extracellular volume
Prior art date
Application number
HK18115179.1A
Other languages
English (en)
Inventor
Vigue Bernard
Rafi-Nikoukhah Homa
Original Assignee
Brahms Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54780102&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1256104(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Brahms Gmbh filed Critical Brahms Gmbh
Publication of HK1256104A1 publication Critical patent/HK1256104A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
HK18115179.1A 2015-11-27 2018-11-27 作為對象的細胞外容量狀態的標誌物的mr-proadm HK1256104A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15196754 2015-11-27
PCT/EP2016/078702 WO2017089474A1 (en) 2015-11-27 2016-11-24 MR-proADM AS MARKER FOR THE EXTRACELLULAR VOLUME STATUS OF A SUBJECT

Publications (1)

Publication Number Publication Date
HK1256104A1 true HK1256104A1 (zh) 2019-09-13

Family

ID=54780102

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18115179.1A HK1256104A1 (zh) 2015-11-27 2018-11-27 作為對象的細胞外容量狀態的標誌物的mr-proadm

Country Status (8)

Country Link
US (1) US20180348235A1 (zh)
EP (1) EP3380845A1 (zh)
JP (1) JP6944449B2 (zh)
CN (1) CN108291918A (zh)
BR (1) BR112018010269A2 (zh)
CA (1) CA3006390A1 (zh)
HK (1) HK1256104A1 (zh)
WO (1) WO2017089474A1 (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019018545A1 (en) 2017-07-18 2019-01-24 The Research Foundation For The State University Of New York BIOMARKERS OF INTRACRANIAL ANEVISM
EP3438668A1 (en) 2017-08-04 2019-02-06 B.R.A.H.M.S GmbH Diagnosis and risk stratification of fungal infections
JP7291688B2 (ja) * 2017-09-13 2023-06-15 ベー．エル．アー．ハー．エム．エス ゲゼルシャフト ミット ベシュレンクテル ハフツング 重篤患者における腎置換療法のための指標としてのアドレノメズリン前駆体
CA3075440A1 (en) * 2017-09-13 2019-03-21 B.R.A.H.M.S Gmbh Pro-adm as a therapy monitoring marker for critcally ill patients
EP3502691A1 (en) * 2017-12-20 2019-06-26 B.R.A.H.M.S GmbH Proadrenomedullin as indicator for renal replacement therapy in critically ill patients
ES2909399T3 (es) 2017-09-13 2022-05-06 Brahms Gmbh Proadrenomedulina como marcador de niveles anormales de plaquetas
EP3729083A1 (en) * 2017-12-20 2020-10-28 B.R.A.H.M.S GmbH Antibiotic therapy guidance based on pro-adm
EP3578989A1 (en) * 2018-06-06 2019-12-11 B.R.A.H.M.S GmbH Pro-adm for prognosis of trauma-related complications in polytrauma patients
WO2020017013A1 (ja) * 2018-07-19 2020-01-23 Ｐｏｓｈ Ｗｅｌｌｎｅｓｓ Ｌａｂｏｒａｔｏｒｙ株式会社 検出装置、シートベルト、及び運転手監視システム
EP3608673A1 (en) * 2018-08-08 2020-02-12 B.R.A.H.M.S GmbH Pro-adm for prognosing the risk of a medical condition requiring hospitalization in patients with symptoms of infectious disease
US10971255B2 (en) * 2018-09-14 2021-04-06 Zasti Inc. Multimodal learning framework for analysis of clinical trials
US11101043B2 (en) 2018-09-24 2021-08-24 Zasti Inc. Hybrid analysis framework for prediction of outcomes in clinical trials
US20230184786A1 (en) * 2020-03-20 2023-06-15 FORSYTH DENTAL INFIRMARY FOR CHILDREN, d/b/a THE FORSYTH INSTITUTE Methods of Detecting and Treating Immune Responses Associated with Viral Infection
KR102544219B1 (ko) * 2021-08-17 2023-06-14 한림대학교 산학협력단 코펩틴의 농도를 이용한 외상성 뇌 손상의 진단 방법
CN114612799B (zh) * 2022-03-11 2022-09-16 应急管理部国家自然灾害防治研究院 基于滑坡/非滑坡面积比的空间自适应正负样本生成方法及系统

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FR2570703B1 (fr) 1984-09-26 1988-07-08 Commissariat Energie Atomique Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents
US4882733A (en) 1987-03-13 1989-11-21 Ford Aerospace Corporation Method and apparatus for combining encoding and modulation
FR2664699B1 (fr) 1990-07-13 1995-08-18 Cis Bio Int Procede d'amplification du signal d'emission d'un compose luminescent.
JP2005532394A (ja) * 2002-07-02 2005-10-27 ガリレオ ファーマシューティカルズ， インコーポレイティド 雌性被験体における炎症性症状および／またはバイオマーカーの低減のための組成物および方法
DE10316583A1 (de) * 2003-04-10 2004-10-28 B.R.A.H.M.S Aktiengesellschaft Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung
US8173596B2 (en) * 2004-05-14 2012-05-08 The University Of North Carolina At Chapel Hill Prouroguanylin, and synthetic analogs or proteolytic cleavage products derived from it, as therapeutic and diagnostic agents for diseases involving salt and/or fluid homeostasis
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EP2108958A1 (en) 2008-04-09 2009-10-14 B.R.A.H.M.S. Aktiengesellschaft Pro-Endothelin-1 for the prediction of impaired peak oxygen consumption
EP2180322A1 (en) * 2008-10-22 2010-04-28 BRAHMS Aktiengesellschaft Prognostic biomarkers for the progression of primary chronic kidney disease
US20120003672A1 (en) * 2008-10-31 2012-01-05 B.R.A.H.M.S Gmbh In vitro-method for the diagnosis, prognosis, monitoring and therapy follow-up of disorders associated with the metabolic syndrome, a cardiovascular disease and/or insulin resistance
ES2431358T3 (es) * 2008-11-11 2013-11-26 B.R.A.H.M.S Gmbh Pronóstico y evaluación del riesgo en pacientes que padecen insuficiencia cardíaca mediante la determinación de la concentración de ADM
CN101825627B (zh) * 2009-03-02 2013-10-02 江苏迈迪基因生物科技有限公司 心力衰竭的生物标志物的联合并行检测方法及诊断试剂盒
WO2010128071A1 (en) * 2009-05-05 2010-11-11 Brahms Ag Vasoactive hormone-based stratification of patients suffering from diseases related to endothelial function/dysfunction
EP3032261B1 (en) * 2010-06-18 2018-05-23 B.R.A.H.M.S GmbH Mr-pro-amd for the prediction of incident cancer in males subject below the age of 57.9 years
MY174877A (en) * 2011-11-16 2020-05-20 Adrenomed Ag Anti-adrenomedullin (adm) antibpdy or anti-adm antibody fragment of anti-adm non-ig scaffold for prevention or reduction of organ dysfunction or organ failure in a patient having a chronic of acute disease or acute condition
KR102176469B1 (ko) * 2011-11-16 2020-11-10 아드레노메드 아게 요법에 사용하기 위한 항-아드레노메둘린 (adm) 항체 또는 항-adm 항체 단편 또는 항-adm 비-ig 스캐폴드
PL2780371T3 (pl) * 2011-11-16 2019-06-28 Adrenomed Ag Przeciwciało przeciwko adrenomedulinie (ADM) lub fragment przeciwciała przeciwko ADM lub rusztowanie nie-Ig przeciwko ADM do regulowania równowagi płynów u pacjenta z chorobą przewlekłą lub ostrą
JP6259905B2 (ja) * 2013-03-20 2018-01-10 シュピーンゴテック ゲゼルシャフト ミット ベシュレンクテル ハフツング 血圧降下治療をガイドするアドレノメジュリン

Also Published As

Publication number Publication date
CN108291918A (zh) 2018-07-17
WO2017089474A1 (en) 2017-06-01
CA3006390A1 (en) 2017-06-01
RU2018123169A (ru) 2019-12-30
RU2018123169A3 (zh) 2020-03-24
BR112018010269A2 (pt) 2019-02-05
EP3380845A1 (en) 2018-10-03
JP2019502104A (ja) 2019-01-24
US20180348235A1 (en) 2018-12-06
JP6944449B2 (ja) 2021-10-06

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