HK1256099A1 - 用於治療移植物抗宿主病的組合物和方法 - Google Patents
用於治療移植物抗宿主病的組合物和方法Info
- Publication number
- HK1256099A1 HK1256099A1 HK18115164.8A HK18115164A HK1256099A1 HK 1256099 A1 HK1256099 A1 HK 1256099A1 HK 18115164 A HK18115164 A HK 18115164A HK 1256099 A1 HK1256099 A1 HK 1256099A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- compositions
- methods
- host disease
- versus host
- graft versus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Transplantation (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Marine Sciences & Fisheries (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562207000P | 2015-08-19 | 2015-08-19 | |
PCT/US2016/047595 WO2017031341A1 (en) | 2015-08-19 | 2016-08-18 | Compositions and methods for treating graft versus host disease |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1256099A1 true HK1256099A1 (zh) | 2019-09-13 |
Family
ID=58052028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18115164.8A HK1256099A1 (zh) | 2015-08-19 | 2018-11-27 | 用於治療移植物抗宿主病的組合物和方法 |
Country Status (6)
Country | Link |
---|---|
US (1) | US10898522B2 (zh) |
EP (1) | EP3337491A4 (zh) |
CN (1) | CN108135941B (zh) |
CA (1) | CA2995582A1 (zh) |
HK (1) | HK1256099A1 (zh) |
WO (1) | WO2017031341A1 (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108103027B (zh) * | 2018-02-02 | 2021-12-24 | 中国医学科学院血液病医院(血液学研究所) | 高效率血细胞重编程同时实现基因编辑的方法 |
FR3100715B1 (fr) * | 2019-09-12 | 2023-09-29 | Francais Du Sang Ets | Utilisation de HDL dans la prophylaxie de la maladie du greffon contre l’hôte |
CN114732807A (zh) * | 2022-03-27 | 2022-07-12 | 苏州大学 | 米托蒽醌在制备预防或治疗急性移植物抗宿主病药物中的应用 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2296366A1 (en) * | 1997-07-21 | 1999-01-28 | Cerus Corporation | Method of treating leukocytes, leukocyte compositions and methods of use thereof |
KR20120038546A (ko) * | 2002-11-01 | 2012-04-23 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | HIF-1 알파의 siRNA 억제를 위한 조성물 및 방법 |
WO2004071443A2 (en) * | 2003-02-12 | 2004-08-26 | Irm Llc | Methods and compositions for modulating stem cells |
US7682828B2 (en) | 2003-11-26 | 2010-03-23 | Whitehead Institute For Biomedical Research | Methods for reprogramming somatic cells |
US7629128B2 (en) * | 2004-08-30 | 2009-12-08 | Prolx Pharmaceuticals Corp. | Methods of identifying respondents to hypoxia inducible factor 1-α inhibitors |
US20080213404A1 (en) * | 2005-02-04 | 2008-09-04 | Johnson Randall S | Hif Modulating Compounds and Methods of Use Thereof |
US7312217B2 (en) * | 2005-03-11 | 2007-12-25 | Syntrix Biosystems, Inc. | Aminopterin dosage forms and methods for inflammatory disorders |
US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
US20090227032A1 (en) | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
US20070212360A1 (en) * | 2006-01-17 | 2007-09-13 | Denko Nicholas C | Modulation of mitochondrial oxygen consumption for therapeutic purposes |
CN101269088A (zh) * | 2007-03-23 | 2008-09-24 | 中山大学 | 用于预防与治疗慢性移植物抗宿主病的干细胞制剂 |
CN101687019A (zh) * | 2007-04-24 | 2010-03-31 | 迪亚米德治疗股份公司 | 用于治疗自身免疫性疾病和癌症的药物和方法 |
WO2009001545A1 (ja) * | 2007-06-22 | 2008-12-31 | Sapporo Medical University | 移植片対宿主疾患の検査および治療方法 |
US8669048B2 (en) | 2008-06-24 | 2014-03-11 | Parkinson's Institute | Pluripotent cell lines and methods of use thereof |
NZ590330A (en) * | 2008-07-21 | 2012-08-31 | Immunomedics Inc | Structural variants of anti-cd20 antibodies for improved therapeutic characteristics |
CA2720567C (en) * | 2009-11-09 | 2016-06-21 | The Jackson Laboratory | Transgenic non-human animal and methods for stem cell engraftment |
LT2506840T (lt) * | 2009-12-04 | 2021-06-25 | OncoC4, Inc. | Hipoksija sukeliančio faktoriaus inhibitorių naudojimas |
US8586363B2 (en) | 2009-12-10 | 2013-11-19 | Regents Of The University Of Minnesota | TAL effector-mediated DNA modification |
WO2011146607A2 (en) | 2010-05-18 | 2011-11-24 | President And Fellows Of Harvard College | Stable reprogrammed cells |
EP2658965B1 (en) | 2010-12-31 | 2016-03-02 | Universität für Bodenkultur Wien | Method of generating induced pluripotent stem cells and differentiated cells |
WO2012116111A1 (en) | 2011-02-22 | 2012-08-30 | Sanford-Burnham Medical Research Institute | METHOD AND COMPOUNDS FOR GENERATION OF iPSCs |
EP2691515A2 (en) * | 2011-03-31 | 2014-02-05 | President and Fellows of Harvard College | A unique population of regulatory t cells that regulate tissue regeneration and wound healing |
US20130236453A1 (en) * | 2012-03-12 | 2013-09-12 | The Ohio State University | Methods and Compositions for Modulating Acute Graft-versus-Host Disease using miR-155 Specific Inhibitors |
JP5883539B2 (ja) * | 2012-03-16 | 2016-03-15 | ザ・ジョンズ・ホプキンス・ユニバーシティー | Hif−1阻害剤の送達のための放出制御製剤 |
DK2800811T3 (en) | 2012-05-25 | 2017-07-17 | Univ Vienna | METHODS AND COMPOSITIONS FOR RNA DIRECTIVE TARGET DNA MODIFICATION AND FOR RNA DIRECTIVE MODULATION OF TRANSCRIPTION |
CN104919048B (zh) | 2012-10-01 | 2018-10-26 | 台北荣民总医院 | 制备诱导多能干细胞的方法及其应用 |
US8697359B1 (en) * | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
CN103146646A (zh) * | 2013-02-22 | 2013-06-12 | 浙江大学 | 一种动员间充质干细胞的制剂及分离方法 |
WO2015006725A2 (en) | 2013-07-12 | 2015-01-15 | Cedars-Sinai Medical Center | Generation of induced pluripotent stem cells from normal human mammary epithelial cells |
AU2014359077A1 (en) * | 2013-12-06 | 2016-07-21 | Novimmune S.A. | Anti-TLR4 antibodies and methods of use thereof |
WO2017083403A1 (en) * | 2015-11-10 | 2017-05-18 | Children's Research Institute, Children's National Medical Center | Echinomycin formulation, method of making and method of use thereof |
-
2016
- 2016-08-18 US US15/753,901 patent/US10898522B2/en active Active
- 2016-08-18 CN CN201680061243.3A patent/CN108135941B/zh active Active
- 2016-08-18 EP EP16837853.7A patent/EP3337491A4/en active Pending
- 2016-08-18 CA CA2995582A patent/CA2995582A1/en active Pending
- 2016-08-18 WO PCT/US2016/047595 patent/WO2017031341A1/en active Application Filing
-
2018
- 2018-11-27 HK HK18115164.8A patent/HK1256099A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP3337491A1 (en) | 2018-06-27 |
EP3337491A4 (en) | 2019-04-10 |
WO2017031341A1 (en) | 2017-02-23 |
CN108135941A (zh) | 2018-06-08 |
CA2995582A1 (en) | 2017-02-23 |
US10898522B2 (en) | 2021-01-26 |
CN108135941B (zh) | 2021-07-27 |
US20180236002A1 (en) | 2018-08-23 |
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