HK1252036A1 - 用於治療椎間盤退變性疾病的成纖維細胞 - Google Patents

用於治療椎間盤退變性疾病的成纖維細胞

Info

Publication number
HK1252036A1
HK1252036A1 HK18111368.1A HK18111368A HK1252036A1 HK 1252036 A1 HK1252036 A1 HK 1252036A1 HK 18111368 A HK18111368 A HK 18111368A HK 1252036 A1 HK1252036 A1 HK 1252036A1
Authority
HK
Hong Kong
Prior art keywords
treatment
dermal fibroblasts
disc disease
degenerative disc
degenerative
Prior art date
Application number
HK18111368.1A
Other languages
English (en)
Inventor
Pete O'heeron
Howard An
Original Assignee
Spinalcyte Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spinalcyte Llc filed Critical Spinalcyte Llc
Publication of HK1252036A1 publication Critical patent/HK1252036A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33—Fibroblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
HK18111368.1A 2011-11-09 2018-09-05 用於治療椎間盤退變性疾病的成纖維細胞 HK1252036A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161557479P 2011-11-09 2011-11-09
US201261691391P 2012-08-21 2012-08-21

Publications (1)

Publication Number Publication Date
HK1252036A1 true HK1252036A1 (zh) 2019-05-10

Family

ID=48290533

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18111368.1A HK1252036A1 (zh) 2011-11-09 2018-09-05 用於治療椎間盤退變性疾病的成纖維細胞

Country Status (6)

Country Link
US (3) US20140314726A1 (zh)
EP (3) EP3760707A1 (zh)
CN (2) CN108014339A (zh)
ES (2) ES2653679T3 (zh)
HK (1) HK1252036A1 (zh)
WO (1) WO2013070880A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102389344B (zh) 2006-02-07 2015-12-16 脊柱赛特有限公司 采用机械应变使人皮肤成纤维细胞发生软骨形成分化的方法
WO2014204806A2 (en) 2013-06-19 2014-12-24 Spinalcyte, Llc Adipose cells for chondrocyte applications
US11819555B2 (en) 2013-09-09 2023-11-21 Figene, Llc Gene therapy for the regeneration of chondrocytes or cartilage type cells
WO2017123951A1 (en) * 2016-01-14 2017-07-20 Spinacyte, Llc Cellular blend for the regeneration of chondrocytes or cartilage type cells
CA3049768A1 (en) * 2017-01-11 2018-07-19 Spinalcyte, Llc Methods of enhancing fibroblast therapeutic activity
EP3787650A4 (en) * 2018-05-04 2021-12-29 Spinalcyte, LLC Enhancement of fibroblast plasticity for treatment of disc degeneration
US20210130784A1 (en) * 2018-05-04 2021-05-06 Spinalcyte, Llc De-differentiated fibroblast-conditioned media for stimulation of disc regeneration
CA3099387A1 (en) * 2018-05-04 2019-11-07 Figene, Llc Pain-reducing effects of fibroblasts and treatment of pain
GB2586577B (en) * 2019-06-14 2024-03-27 Gelmetix Ltd Diagnosis and treatment
AU2020368344A1 (en) * 2019-10-13 2022-04-14 Figene, Llc Cannabidiol adjuvant therapy for treatment of disc degenerative disease
CN110693913A (zh) * 2019-10-18 2020-01-17 上海交通大学医学院附属第九人民医院 用于诱导髓核细胞纤维化的物质在制备药物中的用途
EP4200321A1 (en) * 2020-08-12 2023-06-28 Figene, LLC Reduction of covid-19 coagulopathy and other inflammation-associated coagulopathies by administration of fibroblasts

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE389416T1 (de) * 2000-05-16 2008-04-15 Genentech Inc Behandlung von knorpelerkrankungen
WO2002022185A2 (en) * 2000-09-18 2002-03-21 Organogenesis Inc. Method for treating a patient using a cultured connective tissue construct
US20020176893A1 (en) * 2001-02-02 2002-11-28 Wironen John F. Compositions, implants, methods, and kits for closure of lumen openings, repair of ruptured tissue, and for bulking of tissue
CA2479042C (en) * 2002-03-12 2014-05-13 Tissuegene, Inc. Cartilage regeneration using chondrocyte and tgf-.beta.
US8273347B2 (en) * 2003-05-13 2012-09-25 Depuy Spine, Inc. Autologous treatment of degenerated disc with cells
US8043614B2 (en) * 2004-03-09 2011-10-25 Ahlfors Jan-Eric W Autogenic living scaffolds and living tissue matrices: methods and uses thereof
CN102389344B (zh) * 2006-02-07 2015-12-16 脊柱赛特有限公司 采用机械应变使人皮肤成纤维细胞发生软骨形成分化的方法
ES2648128T3 (es) * 2007-07-31 2017-12-28 Lifescan, Inc. Diferenciación de células madre pluripotentes usando células alimentadoras humanas
US7910134B2 (en) * 2007-10-29 2011-03-22 Ayman Boutros Alloplastic injectable dermal filler and methods of use thereof
US20110293666A1 (en) * 2007-11-28 2011-12-01 Xianyan Wang Bioengineered Tissue Constructs and Methods for Production and Use
WO2014204806A2 (en) * 2013-06-19 2014-12-24 Spinalcyte, Llc Adipose cells for chondrocyte applications

Also Published As

Publication number Publication date
EP3290511A1 (en) 2018-03-07
EP2776556A1 (en) 2014-09-17
US20140314726A1 (en) 2014-10-23
EP2776556B1 (en) 2017-11-08
ES2822909T3 (es) 2021-05-05
WO2013070880A1 (en) 2013-05-16
US20180236005A1 (en) 2018-08-23
CN108014339A (zh) 2018-05-11
EP2776556A4 (en) 2015-05-27
ES2653679T3 (es) 2018-02-08
EP3290511B1 (en) 2020-08-26
CN104011201A (zh) 2014-08-27
EP3760707A1 (en) 2021-01-06
US20220047644A1 (en) 2022-02-17

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