HK1250235A1 - 作為rorc調節劑的芳基磺內酰胺衍生物 - Google Patents
作為rorc調節劑的芳基磺內酰胺衍生物Info
- Publication number
- HK1250235A1 HK1250235A1 HK18109703.9A HK18109703A HK1250235A1 HK 1250235 A1 HK1250235 A1 HK 1250235A1 HK 18109703 A HK18109703 A HK 18109703A HK 1250235 A1 HK1250235 A1 HK 1250235A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- sultam derivatives
- aryl
- rorc modulators
- rorc
- modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562190071P | 2015-07-08 | 2015-07-08 | |
US201662345195P | 2016-06-03 | 2016-06-03 | |
PCT/EP2016/066271 WO2017005900A1 (en) | 2015-07-08 | 2016-07-08 | ARYL SULTAM DERIVATIVES AS RORc MODULATORS |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1250235A1 true HK1250235A1 (zh) | 2018-12-07 |
Family
ID=56368995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18109703.9A HK1250235A1 (zh) | 2015-07-08 | 2018-07-26 | 作為rorc調節劑的芳基磺內酰胺衍生物 |
Country Status (6)
Country | Link |
---|---|
US (1) | US10259808B2 (zh) |
EP (1) | EP3319962B1 (zh) |
JP (1) | JP2018519353A (zh) |
CN (1) | CN107690431A (zh) |
HK (1) | HK1250235A1 (zh) |
WO (1) | WO2017005900A1 (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102656934B1 (ko) | 2017-07-10 | 2024-04-16 | 셀진 코포레이션 | 항증식성 화합물 및 이의 사용 방법 |
TWI786303B (zh) * | 2018-06-21 | 2022-12-11 | 大陸商貝達藥業股份有限公司 | 抑制cdk4/6活性化合物的晶型及其應用 |
EP3894402B1 (en) * | 2018-12-14 | 2023-07-05 | F. Hoffmann-La Roche AG | N-containing chromen-4-one derivatives for the treatment and prophylaxis of hepatitis b virus infection |
CN114901640A (zh) * | 2019-12-24 | 2022-08-12 | 兹杜斯生命科学有限公司 | 适用于治疗血脂异常的新型化合物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR092348A1 (es) * | 2012-07-11 | 2015-04-15 | Hoffmann La Roche | DERIVADOS DE ARIL-SULTAMO COMO MODULADORES DE RORc |
CN105916852B (zh) * | 2014-01-10 | 2020-04-24 | 豪夫迈·罗氏有限公司 | 作为RORc调节剂的芳基磺内酰胺衍生物 |
CA2935012A1 (en) * | 2014-01-10 | 2015-07-16 | F. Hoffmann-La Roche Ag | Aryl sultam derivatives as rorc modulators |
US9552885B2 (en) * | 2014-12-10 | 2017-01-24 | Sandisk Technologies Llc | Partial block erase for open block reading in non-volatile memory |
EP3233849A1 (en) * | 2014-12-17 | 2017-10-25 | F. Hoffmann-La Roche AG | HETEROARYLALKYLENE ARYL SULTAM DERIVATIVES AS RORc MODULATORS |
-
2016
- 2016-07-08 WO PCT/EP2016/066271 patent/WO2017005900A1/en active Application Filing
- 2016-07-08 JP JP2018500538A patent/JP2018519353A/ja active Pending
- 2016-07-08 EP EP16736204.5A patent/EP3319962B1/en active Active
- 2016-07-08 CN CN201680033181.5A patent/CN107690431A/zh active Pending
-
2017
- 2017-12-19 US US15/847,407 patent/US10259808B2/en not_active Expired - Fee Related
-
2018
- 2018-07-26 HK HK18109703.9A patent/HK1250235A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP3319962A1 (en) | 2018-05-16 |
EP3319962B1 (en) | 2020-05-13 |
US20180105516A1 (en) | 2018-04-19 |
CN107690431A (zh) | 2018-02-13 |
WO2017005900A1 (en) | 2017-01-12 |
JP2018519353A (ja) | 2018-07-19 |
US10259808B2 (en) | 2019-04-16 |
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