HK1245888A1 - 對癌症的代理功能性診斷測試 - Google Patents
對癌症的代理功能性診斷測試Info
- Publication number
- HK1245888A1 HK1245888A1 HK18105170.1A HK18105170A HK1245888A1 HK 1245888 A1 HK1245888 A1 HK 1245888A1 HK 18105170 A HK18105170 A HK 18105170A HK 1245888 A1 HK1245888 A1 HK 1245888A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cancer
- diagnostics test
- functional diagnostics
- surrogate functional
- surrogate
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Databases & Information Systems (AREA)
- Data Mining & Analysis (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261645253P | 2012-05-10 | 2012-05-10 | |
US201361780252P | 2013-03-13 | 2013-03-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1245888A1 true HK1245888A1 (zh) | 2018-08-31 |
Family
ID=49551473
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18105170.1A HK1245888A1 (zh) | 2012-05-10 | 2018-04-20 | 對癌症的代理功能性診斷測試 |
Country Status (7)
Country | Link |
---|---|
US (2) | US20150301053A1 (zh) |
EP (2) | EP2847592A4 (zh) |
JP (2) | JP2015519565A (zh) |
KR (1) | KR102062416B1 (zh) |
CN (3) | CN111856013A (zh) |
HK (1) | HK1245888A1 (zh) |
WO (1) | WO2013170176A2 (zh) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040171809A1 (en) | 2002-09-09 | 2004-09-02 | Korsmeyer Stanley J. | BH3 peptides and method of use thereof |
EP2008106A2 (en) | 2006-03-31 | 2008-12-31 | Dana-Farber Cancer Institute | Methods of determining cellular chemosensitivity |
WO2014047342A1 (en) | 2012-09-19 | 2014-03-27 | Dana-Farber Cancer Institute, Inc. | Dynamic bh3 profiling |
US20160178612A1 (en) * | 2013-07-18 | 2016-06-23 | Eutropics Pharmaceuticals, Inc. | Differential bh3 mitochondrial profiling |
CA2922503C (en) | 2013-09-19 | 2021-10-26 | Dana-Farber Cancer Institute, Inc. | Methods of bh3 profiling |
US10640803B2 (en) * | 2013-10-30 | 2020-05-05 | Eutropics Pharmaceuticals, Inc. | Methods for determining chemosensitivity and chemotoxicity |
CN107406881B (zh) * | 2015-01-12 | 2021-05-25 | 尤特罗皮克斯制药股份有限公司 | 用于指导癌症治疗的内容相关的诊断测试 |
EP3274467A4 (en) * | 2015-03-24 | 2018-10-31 | Eutropics Pharmaceuticals, Inc. | Surrogate functional biomarker for solid tumor cancer |
CA2982928A1 (en) | 2015-04-20 | 2016-10-27 | Tolero Pharmaceuticals, Inc. | Predicting response to alvocidib by mitochondrial profiling |
EP3289094B1 (en) | 2015-04-27 | 2024-06-05 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for assessing toxicity using dynamic bh3 profiling |
EP3298021B1 (en) | 2015-05-18 | 2019-05-01 | Tolero Pharmaceuticals, Inc. | Alvocidib prodrugs having increased bioavailability |
US10568887B2 (en) | 2015-08-03 | 2020-02-25 | Tolero Pharmaceuticals, Inc. | Combination therapies for treatment of cancer |
CN105653896B (zh) * | 2016-01-22 | 2019-02-12 | 北京圣谷同创科技发展有限公司 | 高通量测序突变检测结果验证方法 |
EP3273240A1 (en) * | 2016-07-17 | 2018-01-24 | Mitogro OÜ | Method for selecting patients responsive for cancer treatments |
WO2018094275A1 (en) | 2016-11-18 | 2018-05-24 | Tolero Pharmaceuticals, Inc. | Alvocidib prodrugs and their use as protein kinase inhibitors |
CN110234659A (zh) | 2016-12-19 | 2019-09-13 | 特雷罗药物股份有限公司 | 用于敏感性分析的分析肽和方法 |
US20180293352A1 (en) * | 2017-04-10 | 2018-10-11 | COTA, Inc. | System and Method for Decision-Making for Determining Initiation and Type of Treatment for Patients with a Progressive Illness |
US11497756B2 (en) | 2017-09-12 | 2022-11-15 | Sumitomo Pharma Oncology, Inc. | Treatment regimen for cancers that are insensitive to BCL-2 inhibitors using the MCL-1 inhibitor alvocidib |
KR20210099066A (ko) | 2018-12-04 | 2021-08-11 | 스미토모 다이니폰 파마 온콜로지, 인크. | 암의 치료를 위한 작용제로서 사용하기 위한 cdk9 억제제 및 그의 다형체 |
CN109813916A (zh) * | 2019-02-15 | 2019-05-28 | 浠思(上海)生物技术有限公司 | 利用HTRF一步法筛选Bcl-2家族成员之间结合的阻断剂的方法 |
JP2022525149A (ja) | 2019-03-20 | 2022-05-11 | スミトモ ダイニッポン ファーマ オンコロジー, インコーポレイテッド | ベネトクラクスが失敗した急性骨髄性白血病(aml)の処置 |
CN115968411A (zh) * | 2020-06-17 | 2023-04-14 | 犹他大学研究基金会 | 基于生物标记的用于蛋白酶体抑制剂治疗的患者选择 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9704444D0 (en) * | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
US20030073661A1 (en) * | 2001-09-24 | 2003-04-17 | Shigemi Matsuyama | Method of modulating or examining Ku70 levels in cells |
US20040171809A1 (en) * | 2002-09-09 | 2004-09-02 | Korsmeyer Stanley J. | BH3 peptides and method of use thereof |
CN1302004C (zh) * | 2003-08-22 | 2007-02-28 | 浙江海正药业股份有限公司 | 一种阿糖胞苷的制备方法 |
CN1981872B (zh) * | 2005-12-12 | 2012-01-25 | 中国医学科学院肿瘤研究所 | Puma在肿瘤放化疗增敏中的新用途 |
EP2008106A2 (en) | 2006-03-31 | 2008-12-31 | Dana-Farber Cancer Institute | Methods of determining cellular chemosensitivity |
US9360473B2 (en) | 2006-08-16 | 2016-06-07 | Eutropics Pharmaceuticals, Inc. | Assay system to identify therapeutic agents |
US8168755B2 (en) | 2008-05-07 | 2012-05-01 | Eutropics Pharmaceuticals, Inc. | Antibodies specific to heterodimers of Bcl-2 family and uses thereof |
CA2751293A1 (en) * | 2009-02-11 | 2010-08-19 | Abbott Laboratories | Methods and compositions for identifying, classifying and monitoring subject having bcl-2 family inhibitor-resistant tumors and cancers |
WO2012088438A1 (en) | 2010-12-22 | 2012-06-28 | Eutropics Pharmaceuticals, Inc. | Compositions and methods useful for treating diseases |
WO2012122370A2 (en) | 2011-03-08 | 2012-09-13 | Eutropics Pharmaceuticals, Inc. | Compositions and methods useful for treating diseases |
EP2660746A1 (en) * | 2012-04-30 | 2013-11-06 | Royal College of Surgeons in Ireland | Dose-response medical outcome model predictor system and method |
US20160178612A1 (en) * | 2013-07-18 | 2016-06-23 | Eutropics Pharmaceuticals, Inc. | Differential bh3 mitochondrial profiling |
US10640803B2 (en) * | 2013-10-30 | 2020-05-05 | Eutropics Pharmaceuticals, Inc. | Methods for determining chemosensitivity and chemotoxicity |
EP3274467A4 (en) * | 2015-03-24 | 2018-10-31 | Eutropics Pharmaceuticals, Inc. | Surrogate functional biomarker for solid tumor cancer |
-
2013
- 2013-05-10 US US14/440,762 patent/US20150301053A1/en not_active Abandoned
- 2013-05-10 CN CN202010528293.6A patent/CN111856013A/zh active Pending
- 2013-05-10 EP EP13787323.8A patent/EP2847592A4/en not_active Withdrawn
- 2013-05-10 JP JP2015511765A patent/JP2015519565A/ja not_active Withdrawn
- 2013-05-10 EP EP17159039.1A patent/EP3236262B1/en active Active
- 2013-05-10 WO PCT/US2013/040585 patent/WO2013170176A2/en active Application Filing
- 2013-05-10 KR KR1020147034524A patent/KR102062416B1/ko active IP Right Grant
- 2013-05-10 CN CN201380036422.8A patent/CN104541170A/zh active Pending
- 2013-05-10 CN CN201710356313.4A patent/CN107315088A/zh active Pending
-
2017
- 2017-10-19 JP JP2017202640A patent/JP6748050B2/ja active Active
- 2017-11-03 US US15/803,148 patent/US20180246106A1/en not_active Abandoned
-
2018
- 2018-04-20 HK HK18105170.1A patent/HK1245888A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP3236262A3 (en) | 2017-11-22 |
JP6748050B2 (ja) | 2020-08-26 |
EP2847592A2 (en) | 2015-03-18 |
EP2847592A4 (en) | 2016-05-04 |
EP3236262A2 (en) | 2017-10-25 |
JP2015519565A (ja) | 2015-07-09 |
KR20150008177A (ko) | 2015-01-21 |
CN107315088A (zh) | 2017-11-03 |
WO2013170176A2 (en) | 2013-11-14 |
US20150301053A1 (en) | 2015-10-22 |
WO2013170176A3 (en) | 2015-01-29 |
US20180246106A1 (en) | 2018-08-30 |
CN104541170A (zh) | 2015-04-22 |
EP3236262B1 (en) | 2019-09-25 |
KR102062416B1 (ko) | 2020-01-03 |
CN111856013A (zh) | 2020-10-30 |
JP2018013498A (ja) | 2018-01-25 |
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