HK1243953A1 - 检测人dpp-4的测定法 - Google Patents

检测人dpp-4的测定法 Download PDF

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Publication number
HK1243953A1
HK1243953A1 HK18103568.6A HK18103568A HK1243953A1 HK 1243953 A1 HK1243953 A1 HK 1243953A1 HK 18103568 A HK18103568 A HK 18103568A HK 1243953 A1 HK1243953 A1 HK 1243953A1
Authority
HK
Hong Kong
Prior art keywords
assay
dpp
detect human
human dpp
antibodies
Prior art date
Application number
HK18103568.6A
Other languages
English (en)
Chinese (zh)
Inventor
Chang Chien-Ying
Xiao Xiaodong
Chowdhury Partha
Original Assignee
Medimmune, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune, Llc filed Critical Medimmune, Llc
Publication of HK1243953A1 publication Critical patent/HK1243953A1/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
HK18103568.6A 2015-01-09 2016-01-08 检测人dpp-4的测定法 HK1243953A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562101697P 2015-01-09 2015-01-09
US62/101,697 2015-01-09
PCT/US2016/012603 WO2016112261A2 (en) 2015-01-09 2016-01-08 Assay to detect human dpp-4

Publications (1)

Publication Number Publication Date
HK1243953A1 true HK1243953A1 (zh) 2018-07-27

Family

ID=56356576

Family Applications (2)

Application Number Title Priority Date Filing Date
HK18103568.6A HK1243953A1 (zh) 2015-01-09 2016-01-08 检测人dpp-4的测定法
HK18103970.8A HK1244444A1 (zh) 2015-01-09 2016-01-08 检测人dpp-4的测定法

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK18103970.8A HK1244444A1 (zh) 2015-01-09 2016-01-08 检测人dpp-4的测定法

Country Status (14)

Country Link
US (2) US10351630B2 (cg-RX-API-DMAC7.html)
EP (1) EP3242686B1 (cg-RX-API-DMAC7.html)
JP (1) JP2018502577A (cg-RX-API-DMAC7.html)
KR (1) KR20170098941A (cg-RX-API-DMAC7.html)
CN (1) CN107206079A (cg-RX-API-DMAC7.html)
AU (1) AU2016205188A1 (cg-RX-API-DMAC7.html)
BR (1) BR112017011724A2 (cg-RX-API-DMAC7.html)
CA (1) CA2970540A1 (cg-RX-API-DMAC7.html)
HK (2) HK1243953A1 (cg-RX-API-DMAC7.html)
IL (1) IL252528A0 (cg-RX-API-DMAC7.html)
MX (1) MX2017008748A (cg-RX-API-DMAC7.html)
RU (1) RU2017127182A (cg-RX-API-DMAC7.html)
SG (1) SG11201705598VA (cg-RX-API-DMAC7.html)
WO (1) WO2016112261A2 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118359716A (zh) * 2023-01-18 2024-07-19 江苏众红生物工程创药研究院有限公司 抗cd26抗体及其用途
CN118791612A (zh) * 2023-04-14 2024-10-18 江苏众红生物工程创药研究院有限公司 靶向cd26的抗原结合蛋白及其药物应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681718A (en) 1986-03-14 1997-10-28 Celltech Limited Methods for enhanced production of tissue plasminogen activator in cell culture using alkanoic acids or salts thereof
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
US7115555B2 (en) * 1998-07-09 2006-10-03 Baylor College Of Medicine Hypohidrotic ectodermal dysplasia genes and proteins
US6573096B1 (en) * 2000-04-01 2003-06-03 The Research Foundation At State University Of New York Compositions and methods for inhibition of cancer invasion and angiogenesis
CA2446806A1 (en) * 2001-05-11 2002-11-21 Board Of Regents, The University Of Texas System Anti-cd26 monoclonal antibodies as therapy for diseases associated with cells expressing cd26
GB0216648D0 (en) 2002-07-18 2002-08-28 Lonza Biologics Plc Method of expressing recombinant protein in CHO cells
EP1631680A2 (en) 2003-05-21 2006-03-08 Bayer HealthCare AG Diagnostics and therapeutics for diseases associated with dipeptidylpeptidase iv (dpp4)
GB0407315D0 (en) 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
EP1725585A2 (en) 2004-03-10 2006-11-29 Lonza Ltd Method for producing antibodies
RU2486204C2 (ru) * 2005-07-22 2013-06-27 Уай'З Терапьютикс Ко., Лтд. Антитела против сd26 и способы их применения
US20090155784A1 (en) 2007-01-22 2009-06-18 Wyeth Assessment of asthma and allergen-dependent gene expression
MX348362B (es) 2008-03-31 2017-06-07 Genentech Inc * Composiciones y metodos para tratar y diagnosticar asma.
US20100221752A2 (en) 2008-10-06 2010-09-02 Somalogic, Inc. Ovarian Cancer Biomarkers and Uses Thereof
US20130310266A1 (en) * 2010-09-03 2013-11-21 Immport Therapeutics, Inc. Methods and Compositions For The Diagnosis And Treatment Of Cancer and Autoimmune Disorders
US20130281876A1 (en) 2010-10-15 2013-10-24 Medimmune Limited Therapies for improving pulmonary function
TWI666447B (zh) 2010-12-16 2019-07-21 建南德克公司 關於th2抑制作用之診斷及治療
WO2012158954A1 (en) 2011-05-18 2012-11-22 Medimmune, Llc Methods of diagnosing and treating pulmonary diseases or disorders
EP3099323A4 (en) 2014-01-27 2017-10-04 Medlmmune, LLC Dipeptidyl peptidase-4 (dpp4/cd26) as a peripheral biomarker of il-13 activation in asthmatic lung

Also Published As

Publication number Publication date
US20160200832A1 (en) 2016-07-14
EP3242686A4 (en) 2018-06-06
BR112017011724A2 (pt) 2018-05-15
US20190352425A1 (en) 2019-11-21
HK1244444A1 (zh) 2018-08-10
KR20170098941A (ko) 2017-08-30
AU2016205188A1 (en) 2017-06-22
IL252528A0 (en) 2017-07-31
US10351630B2 (en) 2019-07-16
CA2970540A1 (en) 2016-07-14
WO2016112261A3 (en) 2016-09-01
MX2017008748A (es) 2017-11-17
CN107206079A (zh) 2017-09-26
SG11201705598VA (en) 2017-08-30
JP2018502577A (ja) 2018-02-01
WO2016112261A2 (en) 2016-07-14
RU2017127182A (ru) 2019-02-11
EP3242686B1 (en) 2020-07-08
EP3242686A2 (en) 2017-11-15

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