HK1223829A1 - 用於治療亨廷頓病和其他聚谷氨酰胺疾病的丙酰輔酶 前體 - Google Patents

用於治療亨廷頓病和其他聚谷氨酰胺疾病的丙酰輔酶 前體

Info

Publication number
HK1223829A1
HK1223829A1 HK16112074.6A HK16112074A HK1223829A1 HK 1223829 A1 HK1223829 A1 HK 1223829A1 HK 16112074 A HK16112074 A HK 16112074A HK 1223829 A1 HK1223829 A1 HK 1223829A1
Authority
HK
Hong Kong
Prior art keywords
precursor
treatment
huntington disease
polyglutamine diseases
propionyl coenzyme
Prior art date
Application number
HK16112074.6A
Other languages
English (en)
Inventor
Alexandra Drr
Fanny Mochel
Original Assignee
Inserm (Institut Nat De La Sant Et De La Rech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inserm (Institut Nat De La Sant Et De La Rech filed Critical Inserm (Institut Nat De La Sant Et De La Rech
Publication of HK1223829A1 publication Critical patent/HK1223829A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A23L29/035—Organic compounds containing oxygen as heteroatom
    • A23L29/04—Fatty acids or derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK16112074.6A 2006-12-04 2016-10-20 用於治療亨廷頓病和其他聚谷氨酰胺疾病的丙酰輔酶 前體 HK1223829A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06291873A EP1929995A1 (en) 2006-12-04 2006-12-04 Anaplerotic therapy of Huntington disease and other polyglutamine diseases

Publications (1)

Publication Number Publication Date
HK1223829A1 true HK1223829A1 (zh) 2017-08-11

Family

ID=37733780

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16112074.6A HK1223829A1 (zh) 2006-12-04 2016-10-20 用於治療亨廷頓病和其他聚谷氨酰胺疾病的丙酰輔酶 前體

Country Status (11)

Country Link
US (5) US20100063147A1 (zh)
EP (3) EP1929995A1 (zh)
CY (1) CY1116938T1 (zh)
DK (1) DK2097064T3 (zh)
ES (2) ES2552843T3 (zh)
HK (1) HK1223829A1 (zh)
HU (1) HUE026217T2 (zh)
PL (1) PL2097064T3 (zh)
PT (1) PT2097064E (zh)
SI (1) SI2097064T1 (zh)
WO (1) WO2008068230A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1929995A1 (en) 2006-12-04 2008-06-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Anaplerotic therapy of Huntington disease and other polyglutamine diseases
JP5765839B2 (ja) * 2009-12-05 2015-08-19 国立大学法人名古屋大学 球脊髄性筋萎縮症治療薬
AR079733A1 (es) * 2009-12-30 2012-02-15 Baylor Res Inst Terapia anaplerotica para la enfermedad de alzheimer y el envejecimiento cerebral
WO2011159634A1 (en) * 2010-06-14 2011-12-22 Baylor Research Institute Triheptanoin diet for adult polyglucosan body disease (apbd) treatment
CN104955450A (zh) * 2012-12-13 2015-09-30 达拉斯贝勒研究院 用于治疗葡萄糖转运体1缺乏症的三庚酸甘油酯
WO2015073803A1 (en) 2013-11-14 2015-05-21 The University Of Queensland Neurodegenerative disorders and methods of treatment and diagnosis thereof
US20170161441A1 (en) * 2014-07-02 2017-06-08 Ridge Diagnostics, Inc. Methods and materials for treating pain and depression
CN117298092A (zh) 2016-06-08 2023-12-29 善睿圣医药保健股份有限公司 具有奇数碳的脂类化合物及其作为医药组合物或者营养补充剂的用途

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4025649A (en) 1974-08-19 1977-05-24 Labaz Acetic acid derivatives having pharmacological activity and compositions containing the same
DE3032300A1 (de) 1980-08-27 1982-04-01 Alfred Ing. Wien Lohninger Mittel zur parenteralen ernaehrung
GB2104079B (en) 1981-08-14 1985-08-21 London Polytech New aminoacid isomers, their production and their medicinal use
US4753963A (en) 1985-09-26 1988-06-28 The Procter & Gamble Company Nutritional fat suitable for enteral and parenteral products
JP3486778B2 (ja) 1993-04-02 2004-01-13 三菱ウェルファーマ株式会社 アルツハイマー病予防治療剤
US20090253781A1 (en) 2002-05-24 2009-10-08 Btg International Limited Therapeutic compositions
JP4902906B2 (ja) * 1999-02-05 2012-03-21 ベイラー リサーチ インスティテュート 炭素数が７である脂肪酸を含むトリグリセリドを含有する栄養補助剤または医薬調製物
US6740679B1 (en) * 1999-02-05 2004-05-25 Baylor University Medical Center Nutritional supplement or pharmaceutical preparation comprising triglycerides with seven-carbon fatty acid
WO2001032168A1 (en) 1999-11-03 2001-05-10 Juvenon, Inc. Method of treating benign forgetfulness
ES2323940T3 (es) 2000-05-01 2009-07-28 Accera, Inc. Uso de trigliceridos de cadena media para el tratamiento y prevencion de la enfermedad de alzheimer.
US6835750B1 (en) * 2000-05-01 2004-12-28 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II
JP2006519843A (ja) * 2003-03-06 2006-08-31 アクセラ・インコーポレーテッド 新規化学物質及び代謝異常の治療におけるそれらの使用法
EP1628622A4 (en) 2003-05-20 2008-12-17 Baylor Res Inst FIVE AND FIFTH CARBON FATTY ACIDS FOR THE TREATMENT OF METABOLISM DISORDERS AND AS FOOD SUPPLEMENTS
CA2784585A1 (en) 2004-07-02 2006-02-09 Baylor Research Institute Glycogen or polysaccharide storage disease treatment method
WO2006037069A1 (en) 2004-09-28 2006-04-06 Allergan, Inc. Compositions comprising nb-dnj, ne-dnj or d-glucaro-delta-lactam and their uses for the treatment of pain and other neurological conditions
HUE040002T2 (hu) 2006-04-03 2019-02-28 Accera Inc Ketogén vegyületek alkalmazása korfüggõ memóriazavar kezelésére
CN101573107A (zh) 2006-09-26 2009-11-04 贝勒研究院 营养传感器
EP1929995A1 (en) 2006-12-04 2008-06-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Anaplerotic therapy of Huntington disease and other polyglutamine diseases
PT2650380E (pt) 2007-07-31 2016-01-14 Accera Inc Utilização de testagem genómica e compostos cetogénicos para o tratamento de função cognitiva reduzida
WO2009124250A1 (en) 2008-04-03 2009-10-08 The Trustees Of The University Of Pennsylvania Compositions and methods for detecting tricarboxylic acid (tca) metabolic flux
AR079733A1 (es) 2009-12-30 2012-02-15 Baylor Res Inst Terapia anaplerotica para la enfermedad de alzheimer y el envejecimiento cerebral
US20110301238A1 (en) 2010-06-02 2011-12-08 Borges Karin Seizure related disorders and therapeutic methods thereof
WO2011159634A1 (en) 2010-06-14 2011-12-22 Baylor Research Institute Triheptanoin diet for adult polyglucosan body disease (apbd) treatment
EP3372228A1 (en) 2010-12-23 2018-09-12 Amazentis SA Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders
CN104955450A (zh) 2012-12-13 2015-09-30 达拉斯贝勒研究院 用于治疗葡萄糖转运体1缺乏症的三庚酸甘油酯
WO2015073803A1 (en) 2013-11-14 2015-05-21 The University Of Queensland Neurodegenerative disorders and methods of treatment and diagnosis thereof

Also Published As

Publication number Publication date
PT2097064E (pt) 2015-11-25
ES2552843T3 (es) 2015-12-02
PL2097064T3 (pl) 2016-02-29
US20180021287A1 (en) 2018-01-25
CY1116938T1 (el) 2017-04-05
EP3009135B1 (en) 2020-02-05
EP2097064B1 (en) 2015-08-19
EP3009135A1 (en) 2016-04-20
ES2778525T3 (es) 2020-08-10
US10220014B2 (en) 2019-03-05
US20190365695A1 (en) 2019-12-05
US20140364498A1 (en) 2014-12-11
US20120165405A1 (en) 2012-06-28
HUE026217T2 (en) 2016-05-30
US20100063147A1 (en) 2010-03-11
DK2097064T3 (en) 2015-11-23
SI2097064T1 (sl) 2016-01-29
EP2097064A1 (en) 2009-09-09
WO2008068230A1 (en) 2008-06-12
US9717705B2 (en) 2017-08-01
EP1929995A1 (en) 2008-06-11

Similar Documents

Publication Publication Date Title
HK1223829A1 (zh) 用於治療亨廷頓病和其他聚谷氨酰胺疾病的丙酰輔酶 前體
HK1131141A1 (en) Imidazolothiazole compounds for the treatment of disease
IL197001A0 (en) Combination treatment for metabolic disorders
GB2453188B (en) Use of compounds in the manufacture of medicaments for treatment of regional fat deposits
EP1976377A4 (en) COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
PT2056842E (pt) Galactosil-ceramidas modificadas para coloração e estimulação de células t assassinas naturais
EP2010187A4 (en) CONNECTIONS FOR DISEASES AND FUNCTIONAL DISORDERS
EP1983972A4 (en) COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
ZA200808963B (en) Compounds for the treatment of metabolic disorders
IL194189A0 (en) Combination treatment of metabolic disorders
ZA200805645B (en) Compounds for the treatment of metabolic disorders
IL198196A0 (en) Treatment of demyelinating disorders with soluble lymphotoxin-beta-receptor
PT2056805E (pt) Utilização de derivados de 2,5-di-hidroxibenzeno para o tratamento de reacção tecidular
EP2320939A4 (en) TISSUE CALLICLE FOR THE TREATMENT OF PARKINSON DISEASE
PL2056858T3 (pl) Leczenie stanów chorobowych płuc
GB0611240D0 (en) The treatment of increased sebum production
GB0605376D0 (en) Preparation for the relief of disease
GB0611241D0 (en) The treatment of increased sebum production
GB0707208D0 (en) Novel disease treatments
EP2421554A4 (en) TISSUE KALLICREIN FOR THE TREATMENT OF HUNTINGTON'S DISEASE
IL192851A0 (en) Compounds for the treatment of metabolic disorders
IL195392A0 (en) Compounds for the treatment of metabolic disorders
GB2447884B (en) Treatment for skin disease
GB0623740D0 (en) Treatment of disease
EP1927353A4 (en) MEANS FOR THE TREATMENT OF CORNEAL DISEASES