HK1221736A1 - 在無細胞生物合成系統中對代謝通量的控制 - Google Patents

在無細胞生物合成系統中對代謝通量的控制

Info

Publication number
HK1221736A1
HK1221736A1 HK16109807.6A HK16109807A HK1221736A1 HK 1221736 A1 HK1221736 A1 HK 1221736A1 HK 16109807 A HK16109807 A HK 16109807A HK 1221736 A1 HK1221736 A1 HK 1221736A1
Authority
HK
Hong Kong
Prior art keywords
cell
control
metabolic flux
biosynthetic systems
free
Prior art date
Application number
HK16109807.6A
Other languages
English (en)
Inventor
R Swartz James
Original Assignee
Greenlight Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Greenlight Biosciences Inc filed Critical Greenlight Biosciences Inc
Publication of HK1221736A1 publication Critical patent/HK1221736A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q3/00—Condition responsive control processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
HK16109807.6A 2013-06-05 2016-08-16 在無細胞生物合成系統中對代謝通量的控制 HK1221736A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361831376P 2013-06-05 2013-06-05
PCT/US2014/041009 WO2014197655A1 (en) 2013-06-05 2014-06-05 Control of metabolic flux in cell-free biosynthetic systems

Publications (1)

Publication Number Publication Date
HK1221736A1 true HK1221736A1 (zh) 2017-06-09

Family

ID=52008578

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16109807.6A HK1221736A1 (zh) 2013-06-05 2016-08-16 在無細胞生物合成系統中對代謝通量的控制

Country Status (10)

Country Link
US (1) US20160115558A1 (zh)
EP (1) EP3004335A4 (zh)
JP (1) JP2016520324A (zh)
KR (1) KR20160033685A (zh)
CN (1) CN105378076A (zh)
AU (1) AU2014274932A1 (zh)
CA (1) CA2913999A1 (zh)
HK (1) HK1221736A1 (zh)
SG (1) SG11201509976TA (zh)
WO (1) WO2014197655A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010077806A1 (en) 2008-12-15 2010-07-08 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
JP2013526277A (ja) 2010-05-07 2013-06-24 グリーンライト バイオサイエンシーズ インコーポレーテッド 酵素リロケーションにより代謝経路のフラックスを制御する方法
DK3219796T3 (da) 2010-08-31 2020-12-21 Greenlight Biosciences Inc Fremgangsmåder til kontrol af strømningen i metaboliske reaktionsveje ved hjælp af proteasemanipulation
JP2014526250A (ja) 2011-09-09 2014-10-06 グリーンライト バイオサイエンシーズ インコーポレーテッド カルバペネムの無細胞調製
SG11201504930PA (en) 2012-12-21 2015-07-30 Greenlight Biosciences Inc Cell-free system for converting methane into fuel, pyruvate or isobutanol
EP3030671B1 (en) 2013-08-05 2018-10-03 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
CN107614682B (zh) 2015-03-30 2021-11-09 绿光生物科技股份有限公司 核糖核酸的无细胞生成
CA3020312A1 (en) 2016-04-06 2017-10-12 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
JP7186167B2 (ja) 2017-01-06 2022-12-08 グリーンライト バイオサイエンシーズ インコーポレーテッド 糖の無細胞的生産
MX2020003841A (es) 2017-10-11 2020-11-06 Greenlight Biosciences Inc Métodos y composiciones para la producción de nucleósido trifosfatos y ácidos ribonucleicos.
CA3129926A1 (en) * 2019-02-12 2020-08-20 Biocheminsights, Inc. Cell-free compositions for atp regeneration and uses thereof
JP2020137460A (ja) * 2019-02-28 2020-09-03 株式会社日立製作所 代謝反応による化合物の合成反応を最適化する方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2457523A1 (en) * 2001-08-06 2003-08-14 Vanderbilt University An apparatus and methods for using biological material to discriminate an agent
EA010837B1 (ru) * 2004-03-25 2008-12-30 Зе Боард Оф Трастиз Оф Зе Лилэнд Стэнфорд Джуниор Юниверсити Повышение выхода экспрессии протеина в системах бесклеточного синтеза протеинов путём добавления антипенных присадок
CA2657811C (en) * 2006-06-29 2014-10-21 The Board Of Trustees Of The Leland Stanford Junior University Cell-free synthesis of proteins containing unnatural amino acids
WO2009062190A2 (en) * 2007-11-10 2009-05-14 Joule Biotechnologies, Inc. Hyperphotosynthetic organisms
JP2013526277A (ja) * 2010-05-07 2013-06-24 グリーンライト バイオサイエンシーズ インコーポレーテッド 酵素リロケーションにより代謝経路のフラックスを制御する方法

Also Published As

Publication number Publication date
CN105378076A (zh) 2016-03-02
KR20160033685A (ko) 2016-03-28
WO2014197655A8 (en) 2015-06-25
JP2016520324A (ja) 2016-07-14
CA2913999A1 (en) 2014-12-11
US20160115558A1 (en) 2016-04-28
WO2014197655A1 (en) 2014-12-11
EP3004335A1 (en) 2016-04-13
AU2014274932A1 (en) 2015-12-17
SG11201509976TA (en) 2016-01-28
EP3004335A4 (en) 2017-01-25

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