HK1221402A1 - 用於诱导并调节血管生成的组合物和方法以及用於鉴别血管生成调节剂的方法和实验 - Google Patents
用於诱导并调节血管生成的组合物和方法以及用於鉴别血管生成调节剂的方法和实验 Download PDFInfo
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- HK1221402A1 HK1221402A1 HK16109532.8A HK16109532A HK1221402A1 HK 1221402 A1 HK1221402 A1 HK 1221402A1 HK 16109532 A HK16109532 A HK 16109532A HK 1221402 A1 HK1221402 A1 HK 1221402A1
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- angiogenesis
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A61K9/1629—Organic macromolecular compounds
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C12N5/0691—Vascular smooth muscle cells; 3D culture thereof, e.g. models of blood vessels
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1347—Smooth muscle cells
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- C12N2502/28—Vascular endothelial cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2503/00—Use of cells in diagnostics
- C12N2503/04—Screening or testing on artificial tissues
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
- C12N2533/92—Amnion; Decellularised dermis or mucosa
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
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- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Virology (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361807401P | 2013-04-02 | 2013-04-02 | |
| US201361807401P | 2013-04-02 | ||
| PCT/US2014/032696 WO2014165602A1 (en) | 2013-04-02 | 2014-04-02 | Compositions and methods for induction and modulation of angiogenesis and methods and assays for identifying angiogenesis modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1221402A1 true HK1221402A1 (zh) | 2017-06-02 |
Family
ID=51621067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16109532.8A HK1221402A1 (zh) | 2013-04-02 | 2014-04-02 | 用於诱导并调节血管生成的组合物和方法以及用於鉴别血管生成调节剂的方法和实验 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9821013B2 (https=) |
| EP (1) | EP2981273B1 (https=) |
| JP (1) | JP2016516091A (https=) |
| KR (1) | KR20150139569A (https=) |
| AU (1) | AU2014248198B2 (https=) |
| CA (1) | CA2908562A1 (https=) |
| HK (1) | HK1221402A1 (https=) |
| WO (1) | WO2014165602A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2999420A1 (en) | 2005-09-27 | 2007-04-05 | Tissuetech, Inc. | Amniotic membrane preparations and purified compositions and methods of use |
| WO2012149486A1 (en) | 2011-04-28 | 2012-11-01 | Tissuetech, Inc. | Methods of modulating bone remodeling |
| EP2717888B1 (en) | 2011-06-10 | 2020-09-09 | Tissuetech, Inc. | Methods of processing fetal support tissues |
| HK1221402A1 (zh) | 2013-04-02 | 2017-06-02 | University Of Florida Research Foundation, Inc. | 用於诱导并调节血管生成的组合物和方法以及用於鉴别血管生成调节剂的方法和实验 |
| TW201603818A (zh) | 2014-06-03 | 2016-02-01 | 組織科技股份有限公司 | 組成物及方法 |
| WO2016138025A2 (en) | 2015-02-23 | 2016-09-01 | Tissuetech, Inc. | Apparatuses and methods for treating ophthalmic diseases and disorders |
| TWI720984B (zh) | 2015-05-20 | 2021-03-11 | 美商帝聖工業公司 | 用於防止上皮細胞增生及上皮-間質轉移之組合物及方法 |
| US12551509B2 (en) | 2015-11-18 | 2026-02-17 | Lucina Patent Holdco, Llc | Acellular regenerative products and methods of their manufacture |
| TW201733600A (zh) | 2016-01-29 | 2017-10-01 | 帝聖工業公司 | 胎兒扶持組織物及使用方法 |
| WO2020036245A1 (ko) * | 2018-08-17 | 2020-02-20 | 고려대학교 산학협력단 | 인간 신경줄기세포의 기능강화 및 생산을 위한 태반유래 세포 조건화 배지 및 이의 용도 |
| WO2020081817A1 (en) * | 2018-10-17 | 2020-04-23 | University Of Florida Research Foundation | Magnetically responsive composite microparticles for triggered delivery of biologically active agents |
| CA3135546A1 (en) | 2019-04-04 | 2020-10-08 | THT Biomaterials GmbH | A novel human-material-based platform technology for tissue engineering |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4829000A (en) * | 1985-08-30 | 1989-05-09 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Reconstituted basement membrane complex with biological activity |
| US4994559A (en) | 1985-12-17 | 1991-02-19 | Synergen, Inc. | Human basic fibroblast growth factor |
| JP2770926B2 (ja) * | 1985-12-17 | 1998-07-02 | サイナーゲン インコーポレーテッド | 毛管内皮細胞プロテアーゼ合成、dna合成および遊走を促進することの出来るヒト胎盤血管形成誘導因子 |
| JPS63152322A (ja) * | 1986-09-30 | 1988-06-24 | Ichimaru Pharcos Co Ltd | プラセンタ−組織由来フイブロネクチン含有溶液 |
| CA2005600A1 (en) | 1988-12-20 | 1990-06-20 | Cal-Henrik Heldin | Endothelial cell growth factor |
| AUPM425294A0 (en) | 1994-03-04 | 1994-03-31 | Australian National University, The | In-vitro angiogenesis assay |
| US5770565A (en) | 1994-04-13 | 1998-06-23 | La Jolla Cancer Research Center | Peptides for reducing or inhibiting bone resorption |
| JPH0931100A (ja) * | 1995-07-24 | 1997-02-04 | Nippon Ham Kk | 変性コラーゲン及びその製造方法 |
| JP2003501092A (ja) | 1999-06-07 | 2003-01-14 | エドワーズ ライフサイエンシーズ コーポレイション | 標的化新脈管形成 |
| US7163681B2 (en) | 2000-08-07 | 2007-01-16 | Centocor, Inc. | Anti-integrin antibodies, compositions, methods and uses |
| WO2002053191A1 (en) * | 2001-01-05 | 2002-07-11 | Viromed Limited | Compositions for gene therapy of rheumatoid arthritis including a gene encoding an anti-angiogenic protein or parts thereof |
| AU2003220966A1 (en) * | 2002-04-03 | 2003-10-13 | Naohide Yamashita | Drug containing human placenta-origin mesenchymal cells and process for producing vegf using the cells |
| EP1496878A4 (en) | 2002-04-12 | 2007-12-26 | Celgene Corp | TECHNIQUES FOR IDENTIFYING ANGIOGENESIS MODULATORS, COMPOUNDS DISCOVERED BY THESE TECHNIQUES AND TREATMENT TECHNIQUES USING THESE COMPOUNDS |
| US8940292B2 (en) * | 2003-01-28 | 2015-01-27 | Wake Forest University Health Sciences | Enhancement of angiogenesis to grafts using cells engineered to produce growth factors |
| WO2005003317A2 (en) * | 2003-07-01 | 2005-01-13 | Regents Of The University Of Minnesota | Engineered blood vessels |
| JP2005065661A (ja) * | 2003-08-20 | 2005-03-17 | Akihiro Yamaguchi | ヒト血管内皮細胞のVEGF誘導性活性化及び血管新生におけるIdの役割 |
| US7775965B2 (en) | 2004-03-09 | 2010-08-17 | The Board Of Regents Of The University Of Oklahoma | Decellularized grafts from umbilical cord vessels and process for preparing and using same |
| US8187639B2 (en) * | 2005-09-27 | 2012-05-29 | Tissue Tech, Inc. | Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment |
| CA2999420A1 (en) * | 2005-09-27 | 2007-04-05 | Tissuetech, Inc. | Amniotic membrane preparations and purified compositions and methods of use |
| US8003388B2 (en) * | 2006-03-24 | 2011-08-23 | Nortis, Inc. | Method for creating perfusable microvessel systems |
| US20080131522A1 (en) | 2006-10-03 | 2008-06-05 | Qing Liu | Use of placental biomaterial for ocular surgery |
| CA2700613C (en) | 2007-09-26 | 2022-09-20 | Celgene Cellular Therapeutics | Angiogenic cells from human placental perfusate |
| US8642333B2 (en) * | 2008-02-04 | 2014-02-04 | Massachusetts Institute Of Technology | Particulate delivery vehicles for embryoid bodies |
| JP2011514169A (ja) * | 2008-03-17 | 2011-05-06 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | 幹細胞培養のためのマイクロキャリア |
| US8685634B2 (en) * | 2009-03-06 | 2014-04-01 | University of Pittsburgh—of the Commonwealth System of Higher Education | Neural scaffolds |
| CA2769038A1 (en) * | 2009-07-31 | 2011-02-03 | The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services | Antiangiogenic small molecules and methods of use |
| KR101118017B1 (ko) | 2009-09-04 | 2012-02-24 | (주)차바이오앤디오스텍 | 태반 추출물을 제조하는 방법 및 태반 추출물 |
| EP2521861B1 (de) * | 2010-03-30 | 2015-05-27 | Siemens Aktiengesellschaft | Solarthermisches kraftwerk mit indirekter verdampfung und verfahren zum betrieb eines solchen solarthermischen kraftwerks |
| KR20140071813A (ko) | 2012-12-04 | 2014-06-12 | 삼성전자주식회사 | 파이버 상에 형성된 저항성 메모리 소자 및 그 제종 방법 |
| HK1221402A1 (zh) | 2013-04-02 | 2017-06-02 | University Of Florida Research Foundation, Inc. | 用於诱导并调节血管生成的组合物和方法以及用於鉴别血管生成调节剂的方法和实验 |
-
2014
- 2014-04-02 HK HK16109532.8A patent/HK1221402A1/zh unknown
- 2014-04-02 KR KR1020157031446A patent/KR20150139569A/ko not_active Withdrawn
- 2014-04-02 CA CA2908562A patent/CA2908562A1/en not_active Abandoned
- 2014-04-02 AU AU2014248198A patent/AU2014248198B2/en not_active Ceased
- 2014-04-02 WO PCT/US2014/032696 patent/WO2014165602A1/en not_active Ceased
- 2014-04-02 US US14/243,123 patent/US9821013B2/en active Active
- 2014-04-02 EP EP14779851.6A patent/EP2981273B1/en active Active
- 2014-04-02 JP JP2016506585A patent/JP2016516091A/ja active Pending
-
2015
- 2015-05-07 US US15/309,306 patent/US10300091B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016516091A (ja) | 2016-06-02 |
| KR20150139569A (ko) | 2015-12-11 |
| WO2014165602A1 (en) | 2014-10-09 |
| AU2014248198A1 (en) | 2015-10-29 |
| US20170209497A1 (en) | 2017-07-27 |
| EP2981273A4 (en) | 2016-10-26 |
| US10300091B2 (en) | 2019-05-28 |
| US9821013B2 (en) | 2017-11-21 |
| EP2981273A1 (en) | 2016-02-10 |
| US20140294780A1 (en) | 2014-10-02 |
| EP2981273B1 (en) | 2020-09-16 |
| CA2908562A1 (en) | 2014-10-09 |
| AU2014248198B2 (en) | 2018-11-29 |
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