HK1221190A1 - 炎症性眼科疾病的局部治疗 - Google Patents

炎症性眼科疾病的局部治疗 Download PDF

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Publication number
HK1221190A1
HK1221190A1 HK16109376.7A HK16109376A HK1221190A1 HK 1221190 A1 HK1221190 A1 HK 1221190A1 HK 16109376 A HK16109376 A HK 16109376A HK 1221190 A1 HK1221190 A1 HK 1221190A1
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HK
Hong Kong
Prior art keywords
diseases
nalidixic acid
analogues
local treatment
ophthalmic diseases
Prior art date
Application number
HK16109376.7A
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English (en)
Chinese (zh)
Inventor
Alan Leslie Rothaul
Jeremy Gilbert Vinter
Robert Arthur SCOFFIN
Original Assignee
Cresset Biomolecular Discovery Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB201306411A external-priority patent/GB201306411D0/en
Priority claimed from GB201306413A external-priority patent/GB201306413D0/en
Application filed by Cresset Biomolecular Discovery Limited filed Critical Cresset Biomolecular Discovery Limited
Publication of HK1221190A1 publication Critical patent/HK1221190A1/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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    • A61K9/0012Galenical forms characterised by the site of application
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/00Medicinal preparations characterised by special physical form
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    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
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    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
HK16109376.7A 2013-04-09 2014-04-09 炎症性眼科疾病的局部治疗 HK1221190A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1306411.8 2013-04-09
GB201306411A GB201306411D0 (en) 2013-04-09 2013-04-09 Treatment of inflammatory conditions
GB201306413A GB201306413D0 (en) 2013-04-09 2013-04-09 The local treatment of ophthalmic diseases
GB1306413.4 2013-04-09
PCT/GB2014/051108 WO2014167326A1 (en) 2013-04-09 2014-04-09 The local treatment of inflammatory ophthalmic diseases

Publications (1)

Publication Number Publication Date
HK1221190A1 true HK1221190A1 (zh) 2017-05-26

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ID=50489339

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16109377.6A HK1221166A1 (zh) 2013-04-09 2014-04-09 炎症性病症的治疗
HK16109376.7A HK1221190A1 (zh) 2013-04-09 2014-04-09 炎症性眼科疾病的局部治疗

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK16109377.6A HK1221166A1 (zh) 2013-04-09 2014-04-09 炎症性病症的治疗

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Country Link
US (2) US20160068527A1 (enExample)
EP (2) EP2983788A1 (enExample)
JP (2) JP2016516761A (enExample)
CN (2) CN105555364A (enExample)
AU (2) AU2014252807A1 (enExample)
CA (2) CA2909117A1 (enExample)
GB (2) GB2516137B (enExample)
HK (2) HK1221166A1 (enExample)
RU (2) RU2015145134A (enExample)
WO (2) WO2014167327A1 (enExample)
ZA (2) ZA201507718B (enExample)

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GB2516137B (en) 2016-02-17
CA2909111A1 (en) 2014-10-16
GB201406390D0 (en) 2014-05-21
CA2909117A1 (en) 2014-10-16
GB201406396D0 (en) 2014-05-21
GB2516138A (en) 2015-01-14
GB2516138B (en) 2015-11-25
ZA201507724B (en) 2019-02-27
WO2014167327A1 (en) 2014-10-16
ZA201507718B (en) 2019-11-27
US20160051526A1 (en) 2016-02-25
EP2983788A1 (en) 2016-02-17
HK1221166A1 (zh) 2017-05-26
WO2014167326A1 (en) 2014-10-16
AU2014252808A1 (en) 2015-11-12
US20160068527A1 (en) 2016-03-10
EP2983713A1 (en) 2016-02-17
RU2015145134A3 (enExample) 2018-03-16
AU2014252807A1 (en) 2015-11-12
RU2015145135A (ru) 2017-05-12
RU2015145134A (ru) 2017-05-16
CN105431172A (zh) 2016-03-23
JP2016516762A (ja) 2016-06-09
GB2516137A (en) 2015-01-14
GB2516138C (en) 2015-12-09
CN105555364A (zh) 2016-05-04
JP2016516761A (ja) 2016-06-09

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