HK1219269A1 - 化合物及其生產方法，以及用於生產磷酸奧司他韋的方法 - Google Patents
化合物及其生產方法，以及用於生產磷酸奧司他韋的方法Info
- Publication number
- HK1219269A1 HK1219269A1 HK16107325.3A HK16107325A HK1219269A1 HK 1219269 A1 HK1219269 A1 HK 1219269A1 HK 16107325 A HK16107325 A HK 16107325A HK 1219269 A1 HK1219269 A1 HK 1219269A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- producing
- compound
- well
- oseltamivir phosphate
- same
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 2
- 150000001875 compounds Chemical class 0.000 title 1
- VSZGPKBBMSAYNT-RRFJBIMHSA-N oseltamivir Chemical compound CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1 VSZGPKBBMSAYNT-RRFJBIMHSA-N 0.000 title 1
- 229960002194 oseltamivir phosphate Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011050720A JP5784336B2 (ja) | 2011-03-08 | 2011-03-08 | 化合物、及びその製造方法、並びにリン酸オセルタミビルの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1219269A1 true HK1219269A1 (zh) | 2017-03-31 |
Family
ID=46798047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16107325.3A HK1219269A1 (zh) | 2011-03-08 | 2016-06-23 | 化合物及其生產方法，以及用於生產磷酸奧司他韋的方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8940919B2 (zh) |
| EP (4) | EP2684866A4 (zh) |
| JP (1) | JP5784336B2 (zh) |
| CN (2) | CN105330558A (zh) |
| HK (1) | HK1219269A1 (zh) |
| IL (1) | IL228285A (zh) |
| TW (2) | TWI548615B (zh) |
| WO (1) | WO2012121079A1 (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6106452B2 (ja) * | 2012-12-05 | 2017-03-29 | 公益財団法人微生物化学研究会 | 化合物、及びその製造方法、並びにリン酸オセルタミビルの製造方法 |
| US10316982B2 (en) | 2014-07-10 | 2019-06-11 | Borgwarner Inc. | Curved shunt for solenoid curve shaping |
| CN109890790B (zh) * | 2017-06-20 | 2020-04-21 | 广东东阳光药业有限公司 | 一种奥司他韦及其异构体的制备方法 |
| CN115850102A (zh) * | 2022-12-29 | 2023-03-28 | 浙江工业大学 | 一种奥司他韦的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101475573B (zh) * | 2009-01-21 | 2012-07-25 | 中国科学院上海有机化学研究所 | 抗流感药物达菲中间体、合成方法及其用途 |
| CN101735140A (zh) * | 2009-12-23 | 2010-06-16 | 中国科学院上海有机化学研究所 | 手性胺基化合物、合成方法及其抗流感药物达菲中间体的用途 |
-
2011
- 2011-03-08 JP JP2011050720A patent/JP5784336B2/ja not_active Expired - Fee Related
-
2012
- 2012-02-29 EP EP12755315.4A patent/EP2684866A4/en not_active Withdrawn
- 2012-02-29 EP EP17000930.2A patent/EP3235806A1/en not_active Withdrawn
- 2012-02-29 WO PCT/JP2012/055085 patent/WO2012121079A1/ja unknown
- 2012-02-29 CN CN201510672402.0A patent/CN105330558A/zh active Pending
- 2012-02-29 EP EP17000931.0A patent/EP3235797A1/en not_active Withdrawn
- 2012-02-29 CN CN201280012120.2A patent/CN103402973B/zh not_active Expired - Fee Related
- 2012-02-29 EP EP17000929.4A patent/EP3235796A1/en not_active Withdrawn
- 2012-03-07 TW TW104134540A patent/TWI548615B/zh active
- 2012-03-07 TW TW101107652A patent/TWI540119B/zh not_active IP Right Cessation
-
2013
- 2013-09-03 IL IL228285A patent/IL228285A/en active IP Right Grant
- 2013-09-04 US US14/017,574 patent/US8940919B2/en not_active Expired - Fee Related
-
2016
- 2016-06-23 HK HK16107325.3A patent/HK1219269A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012121079A1 (ja) | 2012-09-13 |
| IL228285A (en) | 2016-11-30 |
| TW201249784A (en) | 2012-12-16 |
| TWI540119B (zh) | 2016-07-01 |
| US8940919B2 (en) | 2015-01-27 |
| CN103402973A (zh) | 2013-11-20 |
| CN105330558A (zh) | 2016-02-17 |
| CN103402973B (zh) | 2015-11-25 |
| US20140046087A1 (en) | 2014-02-13 |
| EP3235796A1 (en) | 2017-10-25 |
| EP2684866A4 (en) | 2015-05-06 |
| JP5784336B2 (ja) | 2015-09-24 |
| TW201604176A (zh) | 2016-02-01 |
| JP2012188356A (ja) | 2012-10-04 |
| EP3235797A1 (en) | 2017-10-25 |
| EP3235806A1 (en) | 2017-10-25 |
| EP2684866A1 (en) | 2014-01-15 |
| TWI548615B (zh) | 2016-09-11 |
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