HK1218861A1 - 包含異煙肼顆粒和利福噴汀顆粒的呈可分散的片劑形式的抗結核病的穩定的藥物組合物及其製備方法 - Google Patents
包含異煙肼顆粒和利福噴汀顆粒的呈可分散的片劑形式的抗結核病的穩定的藥物組合物及其製備方法Info
- Publication number
- HK1218861A1 HK1218861A1 HK16106876.8A HK16106876A HK1218861A1 HK 1218861 A1 HK1218861 A1 HK 1218861A1 HK 16106876 A HK16106876 A HK 16106876A HK 1218861 A1 HK1218861 A1 HK 1218861A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- granules
- rifapentine
- isoniazid
- preparation
- pharmaceutical composition
- Prior art date
Links
- 239000008187 granular material Substances 0.000 title 2
- 230000002365 anti-tubercular Effects 0.000 title 1
- 239000007919 dispersible tablet Substances 0.000 title 1
- 229960003350 isoniazid Drugs 0.000 title 1
- QRXWMOHMRWLFEY-UHFFFAOYSA-N isoniazide Chemical compound NNC(=O)C1=CC=NC=C1 QRXWMOHMRWLFEY-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- WDZCUPBHRAEYDL-GZAUEHORSA-N rifapentine Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)NC=2C(O)=C3C(O)=C4C)C)OC)C4=C1C3=C(O)C=2\C=N\N(CC1)CCN1C1CCCC1 WDZCUPBHRAEYDL-GZAUEHORSA-N 0.000 title 1
- 229960002599 rifapentine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
- A61K31/06—Phenols the aromatic ring being substituted by nitro groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3342CH2013 | 2013-07-26 | ||
| PCT/EP2014/065762 WO2015011162A1 (en) | 2013-07-26 | 2014-07-22 | Anti-tuberculosis stable pharmaceutical composition in a form of a dispersible tablet comprising granules of isoniazid and granules of rifapentine and its process of preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1218861A1 true HK1218861A1 (zh) | 2017-03-17 |
Family
ID=51211798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16106876.8A HK1218861A1 (zh) | 2013-07-26 | 2016-06-15 | 包含異煙肼顆粒和利福噴汀顆粒的呈可分散的片劑形式的抗結核病的穩定的藥物組合物及其製備方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9814680B2 (zh) |
| EP (1) | EP3024444A1 (zh) |
| JP (2) | JP2016539110A (zh) |
| CN (1) | CN105407876B (zh) |
| AU (1) | AU2014295099B2 (zh) |
| CA (1) | CA2918528A1 (zh) |
| CL (1) | CL2016000183A1 (zh) |
| HK (1) | HK1218861A1 (zh) |
| IL (1) | IL243369A0 (zh) |
| MX (1) | MX2016001155A (zh) |
| PE (1) | PE20160245A1 (zh) |
| PH (1) | PH12016500119A1 (zh) |
| RU (1) | RU2694056C2 (zh) |
| SA (1) | SA516370446B1 (zh) |
| SG (2) | SG11201510732VA (zh) |
| TW (1) | TWI630911B (zh) |
| WO (1) | WO2015011162A1 (zh) |
| ZA (1) | ZA201600110B (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2672879C2 (ru) | 2013-07-26 | 2018-11-20 | Санофи | Противотуберкулезная композиция, содержащая рифампицин, изониазид, этамбутол и пиразинамид, и способ ее получения |
| MX2023005395A (es) * | 2020-11-09 | 2023-05-19 | Realta Life Sciences Inc | Formulaciones de peptidos y metodos de uso. |
| CN112730657A (zh) * | 2020-12-18 | 2021-04-30 | 卓和药业集团有限公司 | 利福喷丁含量的分析检测方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1217912A (zh) * | 1997-11-26 | 1999-06-02 | 岑冠新 | 复方利福喷丁制剂及制备方法 |
| TR200200966T1 (tr) * | 2000-08-09 | 2002-09-23 | Panacea Biotec Limited | Tüberkülöz ilaçlarının yeni farmasötik terkipleri ve hazırlanma prosesleri |
| JP4446463B2 (ja) * | 2000-10-16 | 2010-04-07 | 第一三共株式会社 | 口腔内速崩壊性医薬組成物およびその製造方法 |
| BR0116994A (pt) | 2001-04-27 | 2004-03-02 | Lupin Ltd | Um processo aperfeiçoado para a preparação de uma composição que abrange uma combinação de dose fixa (fdc) de quatro drogas antituberculose |
| US20050059719A1 (en) | 2003-09-16 | 2005-03-17 | Badawy Sherif Ibrahim Farag | Solid dosage formulation containing a Factor Xa inhibitor and method |
| TW201434467A (zh) | 2005-10-05 | 2014-09-16 | Otsuka Pharma Co Ltd | 抗結核治療藥物及含彼之套組 |
| JP5105818B2 (ja) * | 2005-10-05 | 2012-12-26 | 大塚製薬株式会社 | 医薬組成物 |
| JPWO2007043452A1 (ja) * | 2005-10-12 | 2009-04-16 | パイオニア株式会社 | 車載撮影装置及び車載カメラの撮影可動範囲測定方法 |
| CN1989966B (zh) | 2005-12-30 | 2011-06-08 | 重庆华邦制药股份有限公司 | 含利福平和异烟肼的药物组合物 |
| CN1857280A (zh) * | 2006-04-11 | 2006-11-08 | 济南帅华医药科技有限公司 | 一种复方抗结核药物缓释制剂 |
| EP2184983A1 (en) * | 2007-08-06 | 2010-05-19 | Insys Therapeutics Inc. | Oral cannabinoid liquid formulations and methods of treatment |
| KR101197277B1 (ko) * | 2009-02-05 | 2012-11-05 | (주) 벡스코아 | 경구용 결핵의 치료용 또는 예방용 고형 제형 |
| AP2012006119A0 (en) | 2009-07-31 | 2012-02-29 | Cadila Pharmaceuticals Ltd | Pharmaceutical composition of isoniazid. |
| US20130129791A1 (en) * | 2010-05-04 | 2013-05-23 | Mahmut Bilgic | Preparations of effervescent formulations comprising second and third generation cephalosporin and uses thereof |
| WO2012013756A2 (fr) | 2010-07-28 | 2012-02-02 | Laboratoires Pharma 5 | Procédé de préparation de comprimés contenant en association la rifampicine, l'isoniazide, la pyrazinamide, et éventuellement l'ethambutol |
| US8470365B2 (en) * | 2010-07-29 | 2013-06-25 | Taiwan Biotech Co., Ltd. | Process for preparation of anti-tubercular combination and pharmaceutical composition prepared therefrom |
| RU2672879C2 (ru) | 2013-07-26 | 2018-11-20 | Санофи | Противотуберкулезная композиция, содержащая рифампицин, изониазид, этамбутол и пиразинамид, и способ ее получения |
| SG11201510730UA (en) | 2013-07-26 | 2016-01-28 | Sanofi Sa | Anti-tuberculosis stable pharmaceutical composition in a form of a coated tablet comprising granules of isoniazid and granules of rifapentine and its process of preparation |
-
2014
- 2014-07-22 JP JP2016528510A patent/JP2016539110A/ja not_active Ceased
- 2014-07-22 US US14/906,885 patent/US9814680B2/en not_active Expired - Fee Related
- 2014-07-22 PE PE2016000090A patent/PE20160245A1/es unknown
- 2014-07-22 RU RU2016106328A patent/RU2694056C2/ru not_active IP Right Cessation
- 2014-07-22 WO PCT/EP2014/065762 patent/WO2015011162A1/en active Application Filing
- 2014-07-22 AU AU2014295099A patent/AU2014295099B2/en not_active Revoked
- 2014-07-22 CN CN201480041954.5A patent/CN105407876B/zh not_active Withdrawn - After Issue
- 2014-07-22 SG SG11201510732VA patent/SG11201510732VA/en unknown
- 2014-07-22 MX MX2016001155A patent/MX2016001155A/es unknown
- 2014-07-22 EP EP14741647.3A patent/EP3024444A1/en not_active Withdrawn
- 2014-07-22 SG SG10201803996WA patent/SG10201803996WA/en unknown
- 2014-07-22 CA CA2918528A patent/CA2918528A1/en not_active Withdrawn
- 2014-07-25 TW TW103125582A patent/TWI630911B/zh active
-
2015
- 2015-12-28 IL IL243369A patent/IL243369A0/en unknown
-
2016
- 2016-01-06 ZA ZA2016/00110A patent/ZA201600110B/en unknown
- 2016-01-19 PH PH12016500119A patent/PH12016500119A1/en unknown
- 2016-01-21 SA SA516370446A patent/SA516370446B1/ar unknown
- 2016-01-22 CL CL2016000183A patent/CL2016000183A1/es unknown
- 2016-06-15 HK HK16106876.8A patent/HK1218861A1/zh unknown
-
2018
- 2018-04-04 JP JP2018072182A patent/JP6476331B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SG10201803996WA (en) | 2018-06-28 |
| TWI630911B (zh) | 2018-08-01 |
| JP2016539110A (ja) | 2016-12-15 |
| CN105407876A (zh) | 2016-03-16 |
| AU2014295099B2 (en) | 2019-07-11 |
| MX2016001155A (es) | 2016-04-29 |
| AU2014295099A1 (en) | 2016-02-11 |
| CN105407876B (zh) | 2019-08-30 |
| ZA201600110B (en) | 2017-04-26 |
| EP3024444A1 (en) | 2016-06-01 |
| US20160184231A1 (en) | 2016-06-30 |
| RU2016106328A (ru) | 2017-08-31 |
| CA2918528A1 (en) | 2015-01-29 |
| WO2015011162A1 (en) | 2015-01-29 |
| SG11201510732VA (en) | 2016-01-28 |
| PH12016500119A1 (en) | 2016-04-25 |
| JP6476331B2 (ja) | 2019-02-27 |
| IL243369A0 (en) | 2016-02-29 |
| SA516370446B1 (ar) | 2018-09-13 |
| RU2694056C2 (ru) | 2019-07-09 |
| US9814680B2 (en) | 2017-11-14 |
| JP2018123147A (ja) | 2018-08-09 |
| CL2016000183A1 (es) | 2016-07-01 |
| TW201601723A (zh) | 2016-01-16 |
| PE20160245A1 (es) | 2016-05-10 |
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