HK1218762A1 - 抗血浆激肽释放酶抗体 - Google Patents

抗血浆激肽释放酶抗体 Download PDF

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Publication number
HK1218762A1
HK1218762A1 HK16106777.8A HK16106777A HK1218762A1 HK 1218762 A1 HK1218762 A1 HK 1218762A1 HK 16106777 A HK16106777 A HK 16106777A HK 1218762 A1 HK1218762 A1 HK 1218762A1
Authority
HK
Hong Kong
Prior art keywords
plasma kallikrein
antibodies
heavy chain
chain variable
variable region
Prior art date
Application number
HK16106777.8A
Other languages
English (en)
Chinese (zh)
Inventor
Andrew Nixon
Jon A. Kenniston
Stephen R. COMEAU
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of HK1218762A1 publication Critical patent/HK1218762A1/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
HK16106777.8A 2013-03-15 2014-03-14 抗血浆激肽释放酶抗体 HK1218762A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361791822P 2013-03-15 2013-03-15
US61/791,822 2013-03-15
PCT/US2014/027100 WO2014152232A2 (en) 2013-03-15 2014-03-14 Anti-plasma kallikrein antibodies

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK42020011110.2A Division HK40021386A (en) 2013-03-15 2016-06-13 Anti-plasma kallikrein antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK42020011110.2A Addition HK40021386A (en) 2013-03-15 2016-06-13 Anti-plasma kallikrein antibodies

Publications (1)

Publication Number Publication Date
HK1218762A1 true HK1218762A1 (zh) 2017-03-10

Family

ID=51581689

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16106777.8A HK1218762A1 (zh) 2013-03-15 2014-03-14 抗血浆激肽释放酶抗体

Country Status (10)

Country Link
US (4) US20160017055A1 (https=)
EP (2) EP2970502A4 (https=)
JP (2) JP2016513682A (https=)
KR (1) KR20150132473A (https=)
CN (3) CN118406688A (https=)
AU (4) AU2014240045A1 (https=)
CA (2) CA2906624A1 (https=)
HK (1) HK1218762A1 (https=)
IL (2) IL292121B2 (https=)
WO (1) WO2014152232A2 (https=)

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SMT201800552T1 (it) 2010-01-06 2018-11-09 Dyax Corp Proteine che legano la callicreina plasmatica
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AU2014240045A1 (en) 2013-03-15 2015-09-10 Dyax Corp. Anti-plasma kallikrein antibodies
EA038532B1 (ru) 2014-01-21 2021-09-10 Такеда Фармасьютикал Компани Лимитед Способ лечения наследственного ангионевротического отека (hae)
US10428158B2 (en) 2014-03-27 2019-10-01 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
CN107405399B (zh) * 2015-01-02 2022-02-08 武田药品工业株式会社 针对血浆激肽释放酶和因子xii的双特异性抗体
KR102607829B1 (ko) * 2015-03-30 2023-12-01 다케다 파머수티컬 컴패니 리미티드 혈장 칼리크레인 저해제 및 유전성 혈관부종 발작을 예방하기 위한 이의 용도
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EP3387018A1 (en) * 2015-12-11 2018-10-17 Dyax Corp. Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack
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CN113056304A (zh) * 2018-08-30 2021-06-29 戴埃克斯有限公司 用于治疗遗传性血管性水肿发作的血浆激肽释放酶抑制剂及其用途
CN114207135A (zh) 2019-06-11 2022-03-18 夏尔人类遗传性治疗公司 用于治疗由失调的血浆激肽释放酶介导的疾病的抗体的腺相关病毒载体递送
EP4090427A1 (en) 2020-01-13 2022-11-23 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating pediatric hereditary angioedema attack
US20230174674A1 (en) * 2020-04-04 2023-06-08 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating acute respiratory distress syndrome
WO2022130014A1 (en) 2020-12-16 2022-06-23 Takeda Pharmaceutical Company Limited Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein
CN114790246A (zh) * 2021-01-25 2022-07-26 成都康弘生物科技有限公司 一种抗体及其用途
CN114790245A (zh) * 2021-01-25 2022-07-26 成都康弘生物科技有限公司 一种抗体及其用途

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Also Published As

Publication number Publication date
EP2970502A2 (en) 2016-01-20
AU2021200144B2 (en) 2024-06-20
AU2019200638A1 (en) 2019-02-21
WO2014152232A2 (en) 2014-09-25
US20160017055A1 (en) 2016-01-21
KR20150132473A (ko) 2015-11-25
CN118406688A (zh) 2024-07-30
US20190185580A1 (en) 2019-06-20
AU2024219756A1 (en) 2024-10-10
IL292121A (en) 2022-06-01
IL292121B2 (en) 2024-02-01
JP2016513682A (ja) 2016-05-16
AU2019200638B2 (en) 2021-01-28
IL241334B (en) 2022-05-01
US20250129182A1 (en) 2025-04-24
US12110343B2 (en) 2024-10-08
BR112015022282A2 (pt) 2017-10-10
US11299553B2 (en) 2022-04-12
IL241334A0 (en) 2015-11-30
AU2021200144A1 (en) 2021-03-18
CA2906624A1 (en) 2014-09-25
WO2014152232A3 (en) 2014-11-13
EP2970502A4 (en) 2016-11-30
JP2020007354A (ja) 2020-01-16
AU2014240045A1 (en) 2015-09-10
EP3594244A1 (en) 2020-01-15
CN111704672A (zh) 2020-09-25
CN111704672B (zh) 2024-06-04
US20230002509A1 (en) 2023-01-05
IL292121B1 (en) 2023-10-01
CN105051068A (zh) 2015-11-11
CA3208188A1 (en) 2014-09-25

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