HK1217293A1 - Method of preventing or treating heart failure - Google Patents

Method of preventing or treating heart failure Download PDF

Info

Publication number
HK1217293A1
HK1217293A1 HK16105288.2A HK16105288A HK1217293A1 HK 1217293 A1 HK1217293 A1 HK 1217293A1 HK 16105288 A HK16105288 A HK 16105288A HK 1217293 A1 HK1217293 A1 HK 1217293A1
Authority
HK
Hong Kong
Prior art keywords
arg
phe
lys
peptide
dmt
Prior art date
Application number
HK16105288.2A
Other languages
English (en)
Chinese (zh)
Inventor
Peter S Rabinovitch
Dao-Fu Dai
Hazel H Szeto
Original Assignee
Cornell University
The University Of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell University, The University Of Washington filed Critical Cornell University
Publication of HK1217293A1 publication Critical patent/HK1217293A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HK16105288.2A 2009-10-05 2016-05-10 Method of preventing or treating heart failure HK1217293A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US248681P 2000-11-16
US24868109P 2009-10-05 2009-10-05
US28948309P 2009-12-23 2009-12-23
US289483P 2009-12-23

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK17107403.7A Division HK1233532B (en) 2009-10-05 2016-05-10 Methods for the prevention or treatment of cardiac fibrosis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK17107403.7A Addition HK1233532B (en) 2009-10-05 2016-05-10 Methods for the prevention or treatment of cardiac fibrosis

Publications (1)

Publication Number Publication Date
HK1217293A1 true HK1217293A1 (en) 2017-01-06

Family

ID=43823652

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16105288.2A HK1217293A1 (en) 2009-10-05 2016-05-10 Method of preventing or treating heart failure

Country Status (7)

Country Link
US (7) US20110082084A1 (enExample)
EP (5) EP2944317A1 (enExample)
JP (6) JP2013506696A (enExample)
CN (2) CN103845724A (enExample)
CA (1) CA2776581C (enExample)
HK (1) HK1217293A1 (enExample)
WO (1) WO2011044044A1 (enExample)

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CN116474071A (zh) * 2013-03-01 2023-07-25 康德生物医疗有限公司 治疗线粒体疾病的方法
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CN112111003B (zh) * 2019-06-20 2022-02-11 中国农业大学 含有me序列的一类新型抑制血小板聚集和抗血栓形成寡肽
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US20230256047A1 (en) * 2020-06-17 2023-08-17 Stealth Biotherapeutics Inc. Methods and compositions for the treatment of muscular dystrophy
GB2614162B (en) 2020-09-09 2024-11-06 Social Profit Network Methods and compositions for delivery of biotin to mitochondria
CN117881411A (zh) 2021-06-01 2024-04-12 艾迪雅生物有限责任公司 用于眼部药物的延长释放药物递送系统和使用方法
CN117384253A (zh) * 2023-08-28 2024-01-12 南京医科大学 一类肽及其衍生物和应用

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Also Published As

Publication number Publication date
JP2016190876A (ja) 2016-11-10
US20110082084A1 (en) 2011-04-07
US20180236025A1 (en) 2018-08-23
CN103845724A (zh) 2014-06-11
EP2944317A1 (en) 2015-11-18
EP2485749A1 (en) 2012-08-15
JP7382607B2 (ja) 2023-11-17
JP2022046811A (ja) 2022-03-23
US20230285499A1 (en) 2023-09-14
EP3120860B1 (en) 2019-06-26
EP3603658A1 (en) 2020-02-05
JP2020097627A (ja) 2020-06-25
JP2018203764A (ja) 2018-12-27
CN102711785A (zh) 2012-10-03
US20210187056A1 (en) 2021-06-24
JP2015163609A (ja) 2015-09-10
US20140100166A1 (en) 2014-04-10
EP3120860A1 (en) 2017-01-25
US20200188470A1 (en) 2020-06-18
EP3603658B1 (en) 2025-01-08
EP2764871A1 (en) 2014-08-13
WO2011044044A1 (en) 2011-04-14
CA2776581A1 (en) 2011-04-14
US12102659B2 (en) 2024-10-01
US20160106800A1 (en) 2016-04-21
JP7017762B2 (ja) 2022-02-09
US11534476B2 (en) 2022-12-27
JP6429835B2 (ja) 2018-11-28
JP2013506696A (ja) 2013-02-28
EP2485749A4 (en) 2013-07-24
CA2776581C (en) 2020-12-15

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