HK1215531A1 - 肽、包括所述肽的藥物組合物及使用所述肽和組合物的方法 - Google Patents
肽、包括所述肽的藥物組合物及使用所述肽和組合物的方法Info
- Publication number
- HK1215531A1 HK1215531A1 HK16103473.2A HK16103473A HK1215531A1 HK 1215531 A1 HK1215531 A1 HK 1215531A1 HK 16103473 A HK16103473 A HK 16103473A HK 1215531 A1 HK1215531 A1 HK 1215531A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- peptides
- compositions
- xbp1cd138
- xbp1
- methods
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title 3
- 108090000765 processed proteins & peptides Proteins 0.000 title 3
- 101150056418 XBP1 gene Proteins 0.000 title 1
- -1 cd138 Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261722446P | 2012-11-05 | 2012-11-05 | |
US201361790780P | 2013-03-15 | 2013-03-15 | |
PCT/US2013/068582 WO2014071402A1 (en) | 2012-11-05 | 2013-11-05 | Xbp1, cd138, and cs1, pharmaceutical compositions that include the peptides, and methods of using such petides and compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1215531A1 true HK1215531A1 (zh) | 2016-09-02 |
Family
ID=49596483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16103473.2A HK1215531A1 (zh) | 2012-11-05 | 2016-03-24 | 肽、包括所述肽的藥物組合物及使用所述肽和組合物的方法 |
Country Status (8)
Country | Link |
---|---|
US (3) | US9950047B2 (zh) |
EP (2) | EP3919069A1 (zh) |
JP (3) | JP6374392B2 (zh) |
CN (2) | CN110787285A (zh) |
AU (3) | AU2013337247B2 (zh) |
CA (1) | CA2888803A1 (zh) |
HK (1) | HK1215531A1 (zh) |
WO (1) | WO2014071402A1 (zh) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9096681B2 (en) | 2008-06-02 | 2015-08-04 | Dana-Farber Cancer Institute, Inc. | XBP1, CD138, and CS1 peptides |
TWI641687B (zh) | 2012-05-29 | 2018-11-21 | 美商再生元醫藥公司 | 生產細胞株增強子 |
JP6374392B2 (ja) | 2012-11-05 | 2018-08-15 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | Xbp1、cd138およびcs1ペプチド、該ペプチドを含有する薬学的組成物、ならびにかかるペプチドおよび組成物を使用する方法 |
US10144778B2 (en) | 2014-03-12 | 2018-12-04 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
US9394365B1 (en) | 2014-03-12 | 2016-07-19 | Yeda Research And Development Co., Ltd | Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease |
US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
US11186640B2 (en) * | 2014-07-31 | 2021-11-30 | The University Of Western Australia | Method for the identification of immunotherapy-drug combinations using a network approach |
US11338026B2 (en) | 2014-09-10 | 2022-05-24 | The University Of Connecticut | Identification of immunologically protective neo-epitopes for the treatment of cancers |
JP2017528143A (ja) * | 2014-09-10 | 2017-09-28 | ザ ユニバーシティ オブ コネチカット | 癌の治療のための免疫防御ネオエピトープ同定 |
WO2016049022A1 (en) * | 2014-09-23 | 2016-03-31 | Board Of Trustees Of Michigan State University | Compositions and methods for modulating an immune response |
EP3503914A1 (en) | 2016-08-23 | 2019-07-03 | Oncopep, Inc. | Peptide vaccines and durvalumab for treating breast cancer |
WO2018039203A1 (en) | 2016-08-23 | 2018-03-01 | Oncopep, Inc. | Peptide vaccines and durvalumab for treating multiple myeloma |
US11517591B2 (en) * | 2017-09-01 | 2022-12-06 | Dana-Farber Cancer Institute, Inc. | Immunogenic peptides specific to BCMA and TACI antigens |
WO2019083960A1 (en) | 2017-10-24 | 2019-05-02 | Oncopep, Inc. | PEPTIDE VACCINES AND HDAC INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA |
EP3700575A1 (en) * | 2017-10-24 | 2020-09-02 | Oncopep, Inc. | Peptide vaccines and pembrolizumab for treating breast cancer |
EP3725370A1 (en) | 2019-04-19 | 2020-10-21 | ImmunoBrain Checkpoint, Inc. | Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease |
US11920202B2 (en) | 2020-04-09 | 2024-03-05 | University Of Connecticut | Unbiased identification of tumor rejection mediating neoepitopes |
EP4337694A1 (en) | 2021-05-12 | 2024-03-20 | Dana-Farber Cancer Institute, Inc. | Lag3 and gal3 inhibitory agents, xbp1, cs1, and cd138 peptides, and methods of use thereof |
WO2023097249A2 (en) * | 2021-11-23 | 2023-06-01 | The University Of Chicago | Compositions and methods for dna binding and transcriptional regulation |
CN115040663B (zh) * | 2022-06-15 | 2023-12-12 | 上海交通大学医学院附属仁济医院 | 溶质载体家族38成员2在制备多发性骨髓瘤治疗药物中的应用 |
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GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
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JP2005503118A (ja) | 2001-02-14 | 2005-02-03 | ジェンザイム・コーポレーション | 改変ペプチドリガンド |
US7041499B2 (en) | 2001-12-12 | 2006-05-09 | University Of North Texas Health Science Center | Immuno activation of CS1 receptor in natural killer cells to inhibit tumor cell growth |
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MX2009001440A (es) | 2006-08-07 | 2009-04-15 | Pdl Biopharma Inc | Composiciones y metodos que utilizan anticuerpos anti-cs1 para tratar mieloma multiple. |
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US9096681B2 (en) * | 2008-06-02 | 2015-08-04 | Dana-Farber Cancer Institute, Inc. | XBP1, CD138, and CS1 peptides |
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JP2013536240A (ja) * | 2010-08-24 | 2013-09-19 | ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション | インターロイキン−13受容体α2ペプチド脳がんワクチン |
JP6374392B2 (ja) | 2012-11-05 | 2018-08-15 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | Xbp1、cd138およびcs1ペプチド、該ペプチドを含有する薬学的組成物、ならびにかかるペプチドおよび組成物を使用する方法 |
-
2013
- 2013-11-05 JP JP2015540873A patent/JP6374392B2/ja active Active
- 2013-11-05 US US14/440,442 patent/US9950047B2/en active Active
- 2013-11-05 CN CN201911000135.7A patent/CN110787285A/zh active Pending
- 2013-11-05 WO PCT/US2013/068582 patent/WO2014071402A1/en active Application Filing
- 2013-11-05 AU AU2013337247A patent/AU2013337247B2/en active Active
- 2013-11-05 CN CN201380067770.1A patent/CN105377288B/zh active Active
- 2013-11-05 CA CA2888803A patent/CA2888803A1/en active Pending
- 2013-11-05 EP EP21171538.8A patent/EP3919069A1/en active Pending
- 2013-11-05 EP EP13792561.6A patent/EP2914278B1/en active Active
-
2016
- 2016-03-24 HK HK16103473.2A patent/HK1215531A1/zh unknown
-
2017
- 2017-08-29 US US15/689,159 patent/US20180133297A1/en not_active Abandoned
-
2018
- 2018-07-19 JP JP2018135739A patent/JP2018172435A/ja not_active Withdrawn
- 2018-11-08 AU AU2018260912A patent/AU2018260912B2/en active Active
-
2021
- 2021-02-10 US US17/172,805 patent/US20210170004A1/en active Pending
- 2021-02-26 AU AU2021201265A patent/AU2021201265A1/en active Pending
- 2021-06-25 JP JP2021105587A patent/JP2021152073A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2015536953A (ja) | 2015-12-24 |
US20150297695A1 (en) | 2015-10-22 |
CN105377288A (zh) | 2016-03-02 |
AU2013337247B2 (en) | 2018-08-09 |
JP6374392B2 (ja) | 2018-08-15 |
WO2014071402A8 (en) | 2015-06-18 |
CN110787285A (zh) | 2020-02-14 |
AU2018260912A1 (en) | 2018-11-29 |
AU2021201265A1 (en) | 2021-03-18 |
EP3919069A1 (en) | 2021-12-08 |
EP2914278B1 (en) | 2021-06-02 |
WO2014071402A1 (en) | 2014-05-08 |
JP2018172435A (ja) | 2018-11-08 |
US20180133297A1 (en) | 2018-05-17 |
US20210170004A1 (en) | 2021-06-10 |
AU2018260912B2 (en) | 2020-11-26 |
US9950047B2 (en) | 2018-04-24 |
EP2914278A1 (en) | 2015-09-09 |
CN105377288B (zh) | 2019-11-15 |
CA2888803A1 (en) | 2014-05-08 |
AU2013337247A8 (en) | 2015-05-21 |
AU2013337247A1 (en) | 2015-05-14 |
AU2013337247A2 (en) | 2015-05-21 |
JP2021152073A (ja) | 2021-09-30 |
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