HK1214553A1 - 用於治疗神经退行性疾病的拉喹莫德和普利多匹定 - Google Patents

用於治疗神经退行性疾病的拉喹莫德和普利多匹定 Download PDF

Info

Publication number
HK1214553A1
HK1214553A1 HK16102362.8A HK16102362A HK1214553A1 HK 1214553 A1 HK1214553 A1 HK 1214553A1 HK 16102362 A HK16102362 A HK 16102362A HK 1214553 A1 HK1214553 A1 HK 1214553A1
Authority
HK
Hong Kong
Prior art keywords
laquinimod
amount
pridopidine
pharmaceutical composition
package
Prior art date
Application number
HK16102362.8A
Other languages
English (en)
Chinese (zh)
Inventor
Hayden Michael
Bar-Zohar Dan
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of HK1214553A1 publication Critical patent/HK1214553A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Mechanical Engineering (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK16102362.8A 2012-09-27 2013-09-27 用於治疗神经退行性疾病的拉喹莫德和普利多匹定 HK1214553A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261706695P 2012-09-27 2012-09-27
US61/706,695 2012-09-27
US201361879004P 2013-09-17 2013-09-17
US61/879,004 2013-09-17
PCT/US2013/062482 WO2014052933A1 (en) 2012-09-27 2013-09-27 Laquinimod and pridopidine for treating neurodegenerative disorders

Publications (1)

Publication Number Publication Date
HK1214553A1 true HK1214553A1 (zh) 2016-07-29

Family

ID=50339469

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16102362.8A HK1214553A1 (zh) 2012-09-27 2013-09-27 用於治疗神经退行性疾病的拉喹莫德和普利多匹定
HK15112317.4A HK1211525A1 (en) 2012-09-27 2013-09-27 Laquinimod and pridopidine for treating neurodegenerative disorders

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK15112317.4A HK1211525A1 (en) 2012-09-27 2013-09-27 Laquinimod and pridopidine for treating neurodegenerative disorders

Country Status (13)

Country Link
US (7) US20150209346A1 (enExample)
EP (1) EP2900330A4 (enExample)
CN (1) CN104902958A (enExample)
AU (1) AU2013323131A1 (enExample)
BR (1) BR112015006623A2 (enExample)
CA (1) CA2884781A1 (enExample)
EA (1) EA201590655A8 (enExample)
HK (2) HK1214553A1 (enExample)
IL (1) IL237742A0 (enExample)
IN (1) IN2015DN03219A (enExample)
MX (1) MX2015003608A (enExample)
WO (1) WO2014052933A1 (enExample)
ZA (1) ZA201502600B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
DK2146961T3 (da) * 2007-04-12 2014-04-28 Ivax Int Gmbh N-oxid- og/eller di-N-oxidderivater af dopaminreceptorstabilisatorer/modulatorer udvisende forbedrede cardiovaskulære bivirkningsprofiler
AU2011298382A1 (en) 2010-09-03 2013-05-02 Teva Pharmaceuticals International Gmbh Deuterated analogs of pridopidine useful as dopaminergic stabilizers
KR20140075703A (ko) 2011-09-07 2014-06-19 아이백스 인터내셔널 게엠베하 프리도피딘 하이드로클로라이드의 다형 형태
US9012476B2 (en) 2011-12-08 2015-04-21 IVAX International GmbH Hydrobromide salt of pridopidine
US11090297B2 (en) 2013-06-21 2021-08-17 Prilenia Neurotherapeutics Ltd. Pridopidine for treating huntington's disease
KR102316933B1 (ko) 2013-06-21 2021-10-26 프리레니아 뉴로테라퓨틱스 엘티디. 헌팅턴병 치료를 위한 프리도피딘의 용도
BR112016014507A2 (pt) * 2013-12-20 2018-05-22 Teva Pharma uso de laquinimod para retardar progressão da doença de huntington
TW201613859A (en) 2014-06-30 2016-04-16 Teva Pharma Analogs of PRIDOPIDINE, their preparation and use
CA2961187A1 (en) * 2014-09-16 2016-03-24 Teva Pharmaceuticals Industries Ltd. Treatment of neurodegenerative diseases with combination of laquinimod and fingolimod
JP2018505147A (ja) 2014-12-22 2018-02-22 テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハー プリドピジンのｌ−酒石酸塩
US11471449B2 (en) 2015-02-25 2022-10-18 Prilenia Neurotherapeutics Ltd. Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
EP4282479A3 (en) 2015-02-25 2024-02-21 Prilenia Neurotherapeutics Ltd. Use of pridopidine to treat depression or anxiety
AR105434A1 (es) 2015-07-22 2017-10-04 Teva Pharmaceuticals Int Gmbh Proceso para preparar pridopidina
WO2017015615A1 (en) * 2015-07-22 2017-01-26 Teva Pharmaceuticals International Gmbh Pridopidine base formulations and their use
WO2017048457A1 (en) * 2015-09-18 2017-03-23 Teva Pharmaceuticals Industries Ltd. Combination of laquinimod and pridopidine to treat multiple sclerosis
IL311081A (en) 2016-08-24 2024-04-01 Prilenia Neurotherapeutics Ltd Use of pyridofidine to treat functional decline
WO2019010491A1 (en) * 2017-07-07 2019-01-10 University Of Pittsburgh-Of The Commonwealth System Of Higher Education COMBINATIONS OF MEDICINES FOR THE PROTECTION AGAINST THE DEATH OF NEURONAL CELLS
BR112020003119A2 (pt) * 2017-08-14 2020-10-13 Prilenia Neurotherapeutics Ltd. método de tratamento de esclerose lateral amiotrófica com pridopidina
IL319305A (en) * 2019-03-15 2025-04-01 Prilenia Neurotherapeutics Ltd Pridopidine and analogues for the treatment of mitochondrial diseases and disorders and symptoms associated with these diseases
EA202193190A1 (ru) * 2019-06-12 2022-03-24 Прилиния Ньюротерапьютикс Лтд. Композиция, включающая придопидин и его аналог, для лечения болезни гентингтона и ее симптомов

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008155357A2 (en) * 2007-06-18 2008-12-24 A. Carlsson Research Ab Use of dopamine stabilizers
WO2010057006A1 (en) * 2008-11-13 2010-05-20 Link Medicine Corporation Azaquinolinone derivatives and uses thereof
ES2731052T3 (es) * 2009-08-10 2019-11-13 Active Biotech Ab Tratamiento de la enfermedad de Huntington usando laquinimod
WO2011107583A1 (en) * 2010-03-04 2011-09-09 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Substituted 4-phenyl-n-alkyl-piperidines for preventing onset or slowing progression of neurodegenerative disorders
JP2013544887A (ja) * 2010-12-07 2013-12-19 テバ ファーマシューティカル インダストリーズ リミティド 多発性硬化症患者において疲労を軽減し、機能状態を改善し、生活の質を改善するための、ラキニモド（ｌａｑｕｉｎｉｍｏｄ）の使用

Also Published As

Publication number Publication date
EP2900330A4 (en) 2016-05-25
CA2884781A1 (en) 2014-04-03
US20140088140A1 (en) 2014-03-27
CN104902958A (zh) 2015-09-09
US20180250285A1 (en) 2018-09-06
IL237742A0 (en) 2015-05-31
EP2900330A1 (en) 2015-08-05
HK1211525A1 (en) 2016-05-27
AU2013323131A1 (en) 2015-05-07
MX2015003608A (es) 2015-06-05
BR112015006623A2 (pt) 2017-07-04
EA201590655A1 (ru) 2015-12-30
US20190117639A1 (en) 2019-04-25
US20180133209A1 (en) 2018-05-17
IN2015DN03219A (enExample) 2015-10-02
ZA201502600B (en) 2016-06-29
US20150209346A1 (en) 2015-07-30
WO2014052933A1 (en) 2014-04-03
US20180369228A1 (en) 2018-12-27
US20170319569A1 (en) 2017-11-09
EA201590655A8 (ru) 2016-07-29

Similar Documents

Publication Publication Date Title
HK1214553A1 (zh) 用於治疗神经退行性疾病的拉喹莫德和普利多匹定
US20140088145A1 (en) Combination of rasagiline and pridopidine for treating neurodegenerative disorders, in particular huntington's disease
JP7069253B2 (ja) 統合失調症を治療するための２－（（１－（２（４－フルオロフェニル）－２－オキソエチル）ピペリジン－４－イル）メチル）イソインドリン－１－オン
TW201321001A (zh) 以拉喹莫德及芬戈莫德之組合治療多發性硬化症
JP2019526571A (ja) 認知症の処置
US20190231768A1 (en) Pridopidine for treating drug induced dyskinesias
EP4512473A2 (en) Methods of treating behavior alterations
TW201408299A (zh) 不含鹼化劑之拉喹莫德（ｌａｑｕｉｎｉｍｏｄ）調配物
WO2017048457A1 (en) Combination of laquinimod and pridopidine to treat multiple sclerosis
MX2010014223A (es) Composiciones pediatricas para el tratamiento de esclerosis multiple.
WO2020110128A1 (en) Combination of pridopidine and an additional therapeutic agent for treating drug induced dyskinesia
WO2015017565A1 (en) Treatment of multiple sclerosis with combination of laquinimod and flupirtine
RU2799049C2 (ru) Способы лечения изменений поведения
EP3049075A2 (en) Laquinimod combination therapy for treatment of multiple sclerosis
HK40122445A (en) Methods of treating behavior alterations
US20160184428A1 (en) Treatment of multiple sclerosis by alemtuzumab induction followed by laquinimod therapy
WO2025154076A1 (en) Method of prolonging the survival of a subject with als
EP3086788A1 (en) Treatment of multiple sclerosis with combination of laquinimod and teriflunomide
HK1225292A1 (en) Laquinimod combination therapy for treatment of multiple sclerosis
NZ715951B2 (en) Therapeutic agents for use in the prophylaxis and/or treatment of hyperkinetic movement disorders
NZ713051A (en) S-enantiomerically enriched compositions of beta blockers for treating amyotrophic lateral sclerosis