HK1214263A1 - 吡唑並噠嗪以及用於治療視網膜變性疾病和與厄舍綜合征綜合征相關的聽力喪失的方法 - Google Patents

吡唑並噠嗪以及用於治療視網膜變性疾病和與厄舍綜合征綜合征相關的聽力喪失的方法

Info

Publication number
HK1214263A1
HK1214263A1 HK16102421.7A HK16102421A HK1214263A1 HK 1214263 A1 HK1214263 A1 HK 1214263A1 HK 16102421 A HK16102421 A HK 16102421A HK 1214263 A1 HK1214263 A1 HK 1214263A1
Authority
HK
Hong Kong
Prior art keywords
pyrazolopyridazines
methods
hearing loss
degenerative diseases
loss associated
Prior art date
Application number
HK16102421.7A
Other languages
English (en)
Chinese (zh)
Inventor
Roland Werner Burli
William Rameshchandra Krishna Esmieu
Christopher James Lock
Karine Fabienne Malagu
Andrew Pate Owens
William Edward Harte
Original Assignee
Usher Iii Initiative Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usher Iii Initiative Inc filed Critical Usher Iii Initiative Inc
Publication of HK1214263A1 publication Critical patent/HK1214263A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK16102421.7A 2012-10-25 2016-03-02 吡唑並噠嗪以及用於治療視網膜變性疾病和與厄舍綜合征綜合征相關的聽力喪失的方法 HK1214263A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261718593P 2012-10-25 2012-10-25
US201361775376P 2013-03-08 2013-03-08
PCT/US2013/066938 WO2014066835A1 (en) 2012-10-25 2013-10-25 Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome

Publications (1)

Publication Number Publication Date
HK1214263A1 true HK1214263A1 (zh) 2016-07-22

Family

ID=50545355

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16102421.7A HK1214263A1 (zh) 2012-10-25 2016-03-02 吡唑並噠嗪以及用於治療視網膜變性疾病和與厄舍綜合征綜合征相關的聽力喪失的方法

Country Status (11)

Country Link
EP (1) EP2912038B1 (ja)
JP (1) JP6290910B2 (ja)
AU (1) AU2013334138B2 (ja)
CA (1) CA2889537C (ja)
ES (1) ES2693166T3 (ja)
HK (1) HK1214263A1 (ja)
IL (1) IL238287B (ja)
PL (1) PL2912038T3 (ja)
TR (1) TR201816028T4 (ja)
WO (1) WO2014066835A1 (ja)
ZA (1) ZA201502654B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2701510T3 (pl) 2011-04-25 2017-07-31 Usher Iii Initiative Inc Pirazolopirydazyny oraz sposoby leczenia zwyrodnieniowych chorób siatkówki i utraty słuchu związanych z zespołem ushera
CA2889494C (en) * 2012-10-25 2018-12-18 Usher Iii Initiative, Inc. Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
US9227976B2 (en) 2012-10-25 2016-01-05 Usher Iii Initiative, Inc. Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03009957A (es) * 2001-04-30 2005-07-25 Vertex Pharma Inhibidores de la gsk-3 y estructuras cristalinas de la proteina gsk-3¦ y complejos de proteina.
US7812166B2 (en) * 2004-10-29 2010-10-12 Abbott Laboratories Kinase inhibitors
AR052559A1 (es) * 2005-01-21 2007-03-21 Astex Therapeutics Ltd Derivados de pirazol para inhibir cdk's y gsk's
AU2008323694A1 (en) * 2007-11-07 2009-05-14 Foldrx Pharmaceuticals, Inc. Modulation of protein trafficking
EP3549934A1 (en) * 2008-06-27 2019-10-09 Celgene CAR LLC Heteroaryl compounds and uses thereof
PL2701510T3 (pl) * 2011-04-25 2017-07-31 Usher Iii Initiative Inc Pirazolopirydazyny oraz sposoby leczenia zwyrodnieniowych chorób siatkówki i utraty słuchu związanych z zespołem ushera
CA2889494C (en) * 2012-10-25 2018-12-18 Usher Iii Initiative, Inc. Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome

Also Published As

Publication number Publication date
IL238287B (en) 2018-07-31
CA2889537C (en) 2017-12-12
WO2014066835A1 (en) 2014-05-01
JP6290910B2 (ja) 2018-03-07
TR201816028T4 (tr) 2018-11-21
ZA201502654B (en) 2016-07-27
PL2912038T3 (pl) 2019-02-28
AU2013334138A1 (en) 2015-05-07
EP2912038A1 (en) 2015-09-02
AU2013334138B2 (en) 2017-07-27
IL238287A0 (en) 2015-06-30
JP2015535256A (ja) 2015-12-10
ES2693166T3 (es) 2018-12-07
EP2912038B1 (en) 2018-08-15
EP2912038A4 (en) 2016-04-20
CA2889537A1 (en) 2014-05-01

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