HK1213551A1 - 作為磷酸二酯酶抑制劑的 -苯基- -吡啶基烷基醇衍生物 - Google Patents
作為磷酸二酯酶抑制劑的 -苯基- -吡啶基烷基醇衍生物Info
- Publication number
- HK1213551A1 HK1213551A1 HK16101442.4A HK16101442A HK1213551A1 HK 1213551 A1 HK1213551 A1 HK 1213551A1 HK 16101442 A HK16101442 A HK 16101442A HK 1213551 A1 HK1213551 A1 HK 1213551A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- phenyl
- alkyl alcohol
- alcohol derivatives
- phosphodiesterase inhibitors
- pyridinyl alkyl
- Prior art date
Links
- 229940082638 cardiac stimulant phosphodiesterase inhibitors Drugs 0.000 title 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12195738 | 2012-12-05 | ||
PCT/EP2013/075540 WO2014086865A1 (en) | 2012-12-05 | 2013-12-04 | 1-phenyl-2-pyridinyl alkyl alcohol derivatives as phosphodiesterase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1213551A1 true HK1213551A1 (zh) | 2016-07-08 |
Family
ID=47325924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16101442.4A HK1213551A1 (zh) | 2012-12-05 | 2016-02-15 | 作為磷酸二酯酶抑制劑的 -苯基- -吡啶基烷基醇衍生物 |
Country Status (14)
Country | Link |
---|---|
US (1) | US9944612B2 (zh) |
EP (1) | EP2928869B1 (zh) |
KR (1) | KR102192739B1 (zh) |
CN (2) | CN104822659A (zh) |
AR (1) | AR093796A1 (zh) |
BR (1) | BR112015012724A2 (zh) |
CA (1) | CA2893628C (zh) |
ES (1) | ES2716142T3 (zh) |
HK (1) | HK1213551A1 (zh) |
PL (1) | PL2928869T3 (zh) |
RU (1) | RU2655170C2 (zh) |
TR (1) | TR201907092T4 (zh) |
TW (1) | TWI628166B (zh) |
WO (1) | WO2014086865A1 (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2216327A1 (en) | 2009-02-06 | 2010-08-11 | CHIESI FARMACEUTICI S.p.A. | Benzoic acid (1-phenyl-2-pyridin-4-yl)ethyl esters as phosphodiesterase inhibitors |
PT3060551T (pt) | 2013-10-22 | 2019-12-09 | Chiesi Farm Spa | Processo para a preparação de um inibidor de pde4 |
AR104829A1 (es) * | 2015-06-01 | 2017-08-16 | Chiesi Farm Spa | Derivados de aminoésteres |
AR104822A1 (es) * | 2015-06-01 | 2017-08-16 | Chiesi Farm Spa | Derivado de aminoésteres |
MA51413A (fr) * | 2017-12-28 | 2021-04-28 | Chiesi Farm Spa | Utilisation de dérivés d'alcool alkylique de 1-phényl-2-pyridinyl pour le traitement de la fibrose kystique |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT652868E (pt) | 1992-07-28 | 2005-01-31 | Aventis Pharma Ltd | Inibidores da fosfodiesterase do amp ciclico |
US5786354A (en) | 1994-06-21 | 1998-07-28 | Celltech Therapeutics, Limited | Tri-substituted phenyl derivatives and processes for their preparation |
CA2345577A1 (en) * | 1998-10-06 | 2000-04-13 | Mari Itoh | 2,3-disubstituted pyridine derivatives, process for the preparation thereof, drug compositions containing the same and intermediates for the preparation |
SE9903995D0 (sv) * | 1999-11-03 | 1999-11-03 | Astra Ab | New combination |
TW200420554A (en) | 2003-03-31 | 2004-10-16 | Kyowa Hakko Kogyo Kk | A intra-airway administrating preparation |
EP2044023B1 (en) * | 2006-07-14 | 2011-01-19 | CHIESI FARMACEUTICI S.p.A. | Derivatives of 1-phenyl-2-pyridynyl alkylene alcohols as phosphodiesterase inhibitors |
JP2008174213A (ja) * | 2006-12-20 | 2008-07-31 | Nsk Ltd | 舵角可変式ステアリング装置 |
EP2022783A1 (en) * | 2007-08-08 | 2009-02-11 | CHIESI FARMACEUTICI S.p.A. | "Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors" |
EP2070913A1 (en) | 2007-12-14 | 2009-06-17 | CHIESI FARMACEUTICI S.p.A. | Ester derivatives as phosphodiesterase inhibitors |
EP2110375A1 (en) | 2008-04-14 | 2009-10-21 | CHIESI FARMACEUTICI S.p.A. | Phosphodiesterase-4 inhibitors belonging to the tertiary amine class |
EP2216327A1 (en) | 2009-02-06 | 2010-08-11 | CHIESI FARMACEUTICI S.p.A. | Benzoic acid (1-phenyl-2-pyridin-4-yl)ethyl esters as phosphodiesterase inhibitors |
UA111198C2 (uk) | 2011-06-06 | 2016-04-11 | К'Єзі Фармачеутічі С.П.А. | Похідні 1-феніл-2-піридинілалкільних спиртів як інгібітори фосфодіестерази |
CN103827088B (zh) | 2011-09-26 | 2017-10-13 | 奇斯药制品公司 | 作为磷酸二酯酶抑制剂的1‑苯基‑2‑吡啶基烷基醇的衍生物 |
BR112014029642A2 (pt) | 2012-06-04 | 2017-06-27 | Chiesi Farm Spa | composto, combinação de um composto, composição farmacêutica, uso de um composto, dispositivo e kit |
-
2013
- 2013-12-04 WO PCT/EP2013/075540 patent/WO2014086865A1/en active Application Filing
- 2013-12-04 EP EP13814850.7A patent/EP2928869B1/en active Active
- 2013-12-04 PL PL13814850T patent/PL2928869T3/pl unknown
- 2013-12-04 BR BR112015012724A patent/BR112015012724A2/pt not_active Application Discontinuation
- 2013-12-04 ES ES13814850T patent/ES2716142T3/es active Active
- 2013-12-04 CN CN201380063353.XA patent/CN104822659A/zh active Pending
- 2013-12-04 CN CN201911008774.8A patent/CN110698459B/zh active Active
- 2013-12-04 AR ARP130104493A patent/AR093796A1/es active IP Right Grant
- 2013-12-04 CA CA2893628A patent/CA2893628C/en active Active
- 2013-12-04 KR KR1020157017275A patent/KR102192739B1/ko active IP Right Grant
- 2013-12-04 RU RU2015121045A patent/RU2655170C2/ru active
- 2013-12-04 TR TR2019/07092T patent/TR201907092T4/tr unknown
- 2013-12-04 TW TW102144352A patent/TWI628166B/zh active
- 2013-12-05 US US14/097,445 patent/US9944612B2/en active Active
-
2016
- 2016-02-15 HK HK16101442.4A patent/HK1213551A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
KR102192739B1 (ko) | 2020-12-18 |
CA2893628C (en) | 2021-11-30 |
RU2015121045A (ru) | 2017-01-11 |
KR20150092214A (ko) | 2015-08-12 |
EP2928869A1 (en) | 2015-10-14 |
BR112015012724A2 (pt) | 2017-07-11 |
WO2014086865A1 (en) | 2014-06-12 |
CA2893628A1 (en) | 2014-06-12 |
CN104822659A (zh) | 2015-08-05 |
CN110698459A (zh) | 2020-01-17 |
US9944612B2 (en) | 2018-04-17 |
US20140155391A1 (en) | 2014-06-05 |
RU2655170C2 (ru) | 2018-05-24 |
ES2716142T3 (es) | 2019-06-10 |
TR201907092T4 (tr) | 2019-06-21 |
CN110698459B (zh) | 2023-05-05 |
TWI628166B (zh) | 2018-07-01 |
AR093796A1 (es) | 2015-06-24 |
TW201439067A (zh) | 2014-10-16 |
PL2928869T3 (pl) | 2019-08-30 |
EP2928869B1 (en) | 2019-02-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL261282A (en) | Furinone compounds as kinase inhibitors | |
HRP20181429T8 (hr) | Novi derivati benzimidazola kao inhibitori kinaze | |
HK1210775A1 (zh) | 作為激酶抑制劑的咪唑並三嗪甲腈 | |
IL234183A (en) | The history of pyrazolotriazine as selective kinase antagonists with cyclin dependence | |
HK1208442A1 (zh) | 作為 激酶抑制劑的取代的吡咯並嘧啶基氨基-苯並噻唑酮 | |
ZA201309150B (en) | Derivatives of 1-phenyl-2-pyridinyl- alkyl alcohols as phosphodiesterase inhibitors | |
EP2900665A4 (en) | TRIAZOLYL DERIVATIVES AS SYK-HEMMER | |
HK1210470A1 (zh) | 用作脂肪酸合成酶抑制劑的氫吡咯並吡咯衍生物 | |
HK1211027A1 (zh) | 作為 抑制劑的吡咯並三嗪酮 | |
HK1205116A1 (zh) | 作為磷酸二酯酶抑制劑的 -苯基- -吡啶基烷基醇的衍生物 | |
EP2863914A4 (en) | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS | |
HK1198251A1 (zh) | 作為磷酸二酯酶抑制劑的- 苯基- -吡啶基烷基醇的衍生物 | |
IL228103A0 (en) | Amino-quinolines as kinase inhibitors | |
HK1210771A1 (zh) | 氮雜吲哚衍生物 | |
EP2685992A4 (en) | AMINO-QUINOLINES AS KINASE INHIBITORS | |
SG11201500973WA (en) | Amino-quinolines as kinase inhibitors | |
HK1210178A1 (zh) | 作為 抑制劑的取代吡啶並吡嗪類化合物 | |
ZA201409497B (en) | Tetrahydroquinazolinone derivatives as parp inhibitors | |
HK1213551A1 (zh) | 作為磷酸二酯酶抑制劑的 -苯基- -吡啶基烷基醇衍生物 | |
HK1211284A1 (zh) | 磷酸二酯酶 型的抑制劑化合物 |