HK1211487A1 - Oncolytic poliovirus for human tumors - Google Patents
Oncolytic poliovirus for human tumorsInfo
- Publication number
- HK1211487A1 HK1211487A1 HK15112399.5A HK15112399A HK1211487A1 HK 1211487 A1 HK1211487 A1 HK 1211487A1 HK 15112399 A HK15112399 A HK 15112399A HK 1211487 A1 HK1211487 A1 HK 1211487A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- human tumors
- oncolytic poliovirus
- oncolytic
- poliovirus
- tumors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/081—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the protein being an albumin, e.g. human serum albumin [HSA], bovine serum albumin [BSA], ovalbumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32671—Demonstrated in vivo effect
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32711—Rhinovirus
- C12N2770/32733—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Psychology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Radiology & Medical Imaging (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261729021P | 2012-11-21 | 2012-11-21 | |
PCT/US2013/071246 WO2014081937A2 (en) | 2012-11-21 | 2013-11-21 | Oncolytic poliovirus for human tumors |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1211487A1 true HK1211487A1 (en) | 2016-05-27 |
Family
ID=50776674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15112399.5A HK1211487A1 (en) | 2012-11-21 | 2015-12-16 | Oncolytic poliovirus for human tumors |
Country Status (9)
Country | Link |
---|---|
US (5) | US20160030497A1 (xx) |
EP (1) | EP2922564B1 (xx) |
JP (5) | JP2016500108A (xx) |
CN (2) | CN104936608A (xx) |
AU (1) | AU2013347945B2 (xx) |
CA (1) | CA2892183C (xx) |
ES (1) | ES2688653T3 (xx) |
HK (1) | HK1211487A1 (xx) |
WO (1) | WO2014081937A2 (xx) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2013347945B2 (en) | 2012-11-21 | 2017-02-02 | Duke University | Oncolytic poliovirus for human tumors |
WO2016201224A1 (en) | 2015-06-10 | 2016-12-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Processes for production and purification of nucleic acid-containing compositions |
CN108026567B (zh) * | 2015-07-31 | 2021-10-22 | 美国政府(由卫生和人类服务部的部长所代表) | 分析病毒来源治疗剂的方法 |
JP6850290B2 (ja) * | 2015-10-15 | 2021-03-31 | デューク ユニバーシティー | 併用療法 |
MX2018007423A (es) | 2015-12-17 | 2018-11-09 | Novartis Ag | Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas. |
DK3432901T3 (da) * | 2016-03-21 | 2021-10-11 | Univ Duke | Sekventiel antikræftbehandling |
AU2017263543A1 (en) * | 2016-05-11 | 2018-12-13 | Ohio State Innovation Foundation | Oncolytic viruses comprising esrage and methods of treating cancer |
CN109414023A (zh) * | 2016-06-29 | 2019-03-01 | 杜克大学 | 用嵌合脊髓灰质炎病毒激活抗原呈递细胞的组合物和方法 |
WO2018067446A1 (en) | 2016-10-06 | 2018-04-12 | Duke University | Detection of cd-155, the poliovirus receptor |
WO2018075357A1 (en) | 2016-10-17 | 2018-04-26 | Duke University | PRODUCTION OF IMMUNOTOXIN D2C7-(scdsFv)-PE38KDEL |
CN109276580B (zh) * | 2017-07-21 | 2021-08-24 | 厦门大学 | 一种用于治疗肿瘤的病毒 |
CA3095591A1 (en) * | 2018-04-02 | 2019-10-10 | Duke University | Neoadjuvant cancer treatment |
CN110387353B (zh) * | 2018-04-16 | 2023-07-18 | 厦门大学 | 一种用于治疗肿瘤的柯萨奇b组病毒 |
US20220387529A1 (en) * | 2019-11-04 | 2022-12-08 | Duke University | Treatment for primary and metastatic cancer |
US20210196813A1 (en) * | 2019-12-27 | 2021-07-01 | Rush University Medical Center | Utilizing Vaccines to Treat Cancer and Enhance the Success Rate of Cancer Immunotherapy |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5541100A (en) * | 1990-09-12 | 1996-07-30 | Rutgers University | Chimeric rhinoviruses |
US6264940B1 (en) * | 1998-08-05 | 2001-07-24 | The Research Foundation Of State University Of New York | Recombinant poliovirus for the treatment of cancer |
US6518033B1 (en) | 1998-08-05 | 2003-02-11 | The Research Foundation Of State University Of New York | Method of detecting the presence of CD155 for diagnosis of cancer and to determine treatment |
US8066983B2 (en) * | 2008-03-14 | 2011-11-29 | The Research Foundation Of State University Of New York | Attenuated poliovirus |
US8076070B2 (en) | 2008-08-06 | 2011-12-13 | University Of Southern California | Genome-wide chromosome conformation capture |
EP2629803A2 (en) * | 2010-10-20 | 2013-08-28 | Mount Sinai School Of Medicine | Methods and compositions for treating tumors using myeloid derived suppressor cells |
BR112013017096A2 (pt) * | 2011-01-04 | 2020-09-01 | Jennerex Inc. | composição e métodos de indução de resposta citotóxica dependente de complemento mediado por anticorpo específico de tumor em animal tendo tumor, de geração de anticorpos in vivo, de inibição do crescimento ou morte de célula de câncer, para tratar indivíduo com câncer, para adaptar de terapia de câncer para indivíduo com câncer e para identificar antígeno específico de tumor |
AU2013347945B2 (en) | 2012-11-21 | 2017-02-02 | Duke University | Oncolytic poliovirus for human tumors |
-
2013
- 2013-11-21 AU AU2013347945A patent/AU2013347945B2/en active Active
- 2013-11-21 CN CN201380070749.7A patent/CN104936608A/zh active Pending
- 2013-11-21 ES ES13856989.2T patent/ES2688653T3/es active Active
- 2013-11-21 WO PCT/US2013/071246 patent/WO2014081937A2/en active Application Filing
- 2013-11-21 CA CA2892183A patent/CA2892183C/en active Active
- 2013-11-21 EP EP13856989.2A patent/EP2922564B1/en active Active
- 2013-11-21 CN CN202110369359.6A patent/CN113143975A/zh active Pending
- 2013-11-21 JP JP2015544130A patent/JP2016500108A/ja not_active Withdrawn
- 2013-11-21 US US14/646,233 patent/US20160030497A1/en not_active Abandoned
-
2015
- 2015-12-16 HK HK15112399.5A patent/HK1211487A1/xx unknown
-
2017
- 2017-02-09 US US15/428,510 patent/US10398743B2/en active Active
- 2017-04-21 JP JP2017084158A patent/JP2017171668A/ja not_active Withdrawn
-
2019
- 2019-07-09 US US16/505,771 patent/US10799543B2/en active Active
- 2019-07-09 JP JP2019127280A patent/JP6862499B6/ja active Active
-
2020
- 2020-09-10 US US17/016,699 patent/US11406677B2/en active Active
-
2021
- 2021-03-31 JP JP2021059723A patent/JP2021100973A/ja active Pending
-
2022
- 2022-07-05 US US17/857,534 patent/US11813298B2/en active Active
-
2023
- 2023-05-02 JP JP2023075928A patent/JP2023087031A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2021100973A (ja) | 2021-07-08 |
US20220339223A1 (en) | 2022-10-27 |
JP2023087031A (ja) | 2023-06-22 |
AU2013347945B2 (en) | 2017-02-02 |
JP2016500108A (ja) | 2016-01-07 |
CA2892183C (en) | 2019-03-26 |
EP2922564A4 (en) | 2016-05-25 |
US10398743B2 (en) | 2019-09-03 |
JP2019189649A (ja) | 2019-10-31 |
CN113143975A (zh) | 2021-07-23 |
CA2892183A1 (en) | 2014-05-30 |
WO2014081937A2 (en) | 2014-05-30 |
JP6862499B6 (ja) | 2021-06-02 |
JP2017171668A (ja) | 2017-09-28 |
EP2922564A2 (en) | 2015-09-30 |
US11406677B2 (en) | 2022-08-09 |
US20170216382A1 (en) | 2017-08-03 |
AU2013347945A1 (en) | 2015-06-04 |
JP6862499B2 (ja) | 2021-04-21 |
ES2688653T3 (es) | 2018-11-06 |
CN104936608A (zh) | 2015-09-23 |
US11813298B2 (en) | 2023-11-14 |
US10799543B2 (en) | 2020-10-13 |
US20190343904A1 (en) | 2019-11-14 |
EP2922564B1 (en) | 2018-07-04 |
US20160030497A1 (en) | 2016-02-04 |
US20200405795A1 (en) | 2020-12-31 |
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