HK1209638A1 - 藥物組合物 - Google Patents

藥物組合物

Info

Publication number
HK1209638A1
HK1209638A1 HK15110448.0A HK15110448A HK1209638A1 HK 1209638 A1 HK1209638 A1 HK 1209638A1 HK 15110448 A HK15110448 A HK 15110448A HK 1209638 A1 HK1209638 A1 HK 1209638A1
Authority
HK
Hong Kong
Prior art keywords
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
HK15110448.0A
Other languages
English (en)
Inventor
Shenshen Cai
Brian Alvin Johns
Andrew Spaltenstein
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of HK1209638A1 publication Critical patent/HK1209638A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
HK15110448.0A 2012-12-14 2015-10-23 藥物組合物 HK1209638A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261737177P 2012-12-14 2012-12-14
PCT/US2013/075196 WO2014093941A1 (en) 2012-12-14 2013-12-14 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
HK1209638A1 true HK1209638A1 (zh) 2016-04-08

Family

ID=50935020

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15110448.0A HK1209638A1 (zh) 2012-12-14 2015-10-23 藥物組合物

Country Status (20)

Country Link
US (2) US9795619B2 (zh)
EP (1) EP2931285A4 (zh)
JP (1) JP2016503030A (zh)
KR (1) KR20150093819A (zh)
CN (1) CN104902905A (zh)
AU (1) AU2013358897B2 (zh)
BR (1) BR112015013695A2 (zh)
CA (1) CA2893959A1 (zh)
CL (1) CL2015001660A1 (zh)
CR (1) CR20150313A (zh)
EA (1) EA201590862A1 (zh)
HK (1) HK1209638A1 (zh)
IL (1) IL238807A0 (zh)
MA (1) MA38182A1 (zh)
MX (1) MX2015007563A (zh)
PE (1) PE20151326A1 (zh)
PH (1) PH12015501156A1 (zh)
SG (2) SG11201503807TA (zh)
WO (1) WO2014093941A1 (zh)
ZA (1) ZA201503594B (zh)

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JO3387B1 (ar) 2011-12-16 2019-03-13 Glaxosmithkline Llc مشتقات بيتولين
SG11201503807TA (en) * 2012-12-14 2015-06-29 Glaxosmithkline Llc Pharmaceutical compositions
ME02400B (me) 2012-12-21 2016-09-20 Gilead Sciences Inc Policiklična karbamoilpiridonska jedinjenja i njihova farmaceutska upotreba
WO2014105926A1 (en) 2012-12-31 2014-07-03 Hetero Research Foundation Novel betulinic acid proline derivatives as hiv inhibitors
NO2865735T3 (zh) 2013-07-12 2018-07-21
HUE037347T2 (hu) 2013-07-12 2018-08-28 Gilead Sciences Inc Policiklusos karmaboilpiridon vegyületek és alkalmazásuk HIV fertõzések kezelésére
NO2717902T3 (zh) 2014-06-20 2018-06-23
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
TWI677489B (zh) 2014-06-20 2019-11-21 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
US20170129916A1 (en) 2014-06-26 2017-05-11 Hetero Research Foundation Novel betulinic proline imidazole derivatives as hiv inhibitors
BR112017006005A2 (pt) 2014-09-26 2017-12-19 Glaxosmithkline Ip No 2 Ltd composição farmacêutica, e, método de prevenção ou tratamento de uma infecção por hiv.
TWI738321B (zh) 2014-12-23 2021-09-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
MA40886B1 (fr) 2015-02-09 2020-03-31 Hetero Research Foundation Nouveau triterpénone en c-3 avec des dérivés d'amide inverse en c-28 en tant qu'inhibiteurs du vih
US10370405B2 (en) 2015-03-16 2019-08-06 Hetero Labs Limited C-3 novel triterpenone with C-28 amide derivatives as HIV inhibitors
JP6402259B2 (ja) 2015-04-02 2018-10-10 ギリアード サイエンシーズ， インコーポレイテッド 多環式カルバモイルピリドン化合物およびそれらの薬学的使用
WO2018042332A1 (en) * 2016-08-31 2018-03-08 Glaxosmithkline Intellectual Property (No.2) Limited Combinations and uses and treatments thereof
WO2018042331A1 (en) * 2016-08-31 2018-03-08 Glaxosmithkline Intellectual Property (No.2) Limited Combinations and uses and treatments thereof
CN111107850A (zh) 2017-07-21 2020-05-05 Viiv保健公司 用于治疗hib感染和aids的方案

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WO2005112929A2 (en) 2004-05-20 2005-12-01 Cornell Research Foundation, Inc. Anti-hiv-1 activity of betulinol derivatives
TW200628161A (en) 2004-11-12 2006-08-16 Panacos Pharmaceuticals Inc Novel betulin derivatives, preparation thereof and use thereof
CN1682740A (zh) * 2005-03-11 2005-10-19 中国药科大学 五环三萜类化合物在制备糖原磷酸化酶抑制剂中的应用
WO2006105356A2 (en) 2005-03-29 2006-10-05 Regents Of The University Of Minnesota Methods of manufacturing bioactive 3-esters of betulinic aldehyde and betulinic acid
TWI457136B (zh) 2005-04-04 2014-10-21 Tibotec Pharm Ltd Ｈｉｖ-感染之預防
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FI121468B (fi) 2006-06-07 2010-11-30 Valtion Teknillinen Betuliiniperäiset yhdisteet antimikrobisina aineina
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AU2011215986A1 (en) * 2010-02-11 2012-08-30 Glaxosmithkline Llc Derivatives of betulin
TWI577377B (zh) * 2010-09-16 2017-04-11 Ｖｉｉｖ醫療保健公司 醫藥組合物
WO2013020246A1 (en) 2011-08-08 2013-02-14 Glaxosmithkline Llc Methylene derivatives of betulin
WO2013020245A1 (en) 2011-08-08 2013-02-14 Glaxosmithkline Llc Carbonyl derivatives of betulin
BR112014014046A2 (pt) 2011-12-14 2017-06-13 Glaxosmithkline Llc composto, composição, e, método para tratar hiv
JO3387B1 (ar) 2011-12-16 2019-03-13 Glaxosmithkline Llc مشتقات بيتولين
US20150209273A1 (en) 2012-08-28 2015-07-30 Glaxosmithkline Llc Pharmaceutical Compositions
SG11201503807TA (en) * 2012-12-14 2015-06-29 Glaxosmithkline Llc Pharmaceutical compositions
BR112017006005A2 (pt) 2014-09-26 2017-12-19 Glaxosmithkline Ip No 2 Ltd composição farmacêutica, e, método de prevenção ou tratamento de uma infecção por hiv.

Also Published As

Publication number Publication date
CA2893959A1 (en) 2014-06-19
MA38182A1 (fr) 2018-04-30
PE20151326A1 (es) 2015-10-12
KR20150093819A (ko) 2015-08-18
IL238807A0 (en) 2015-06-30
EP2931285A1 (en) 2015-10-21
CL2015001660A1 (es) 2015-10-02
JP2016503030A (ja) 2016-02-01
US20150313917A1 (en) 2015-11-05
AU2013358897A1 (en) 2015-07-02
AU2013358897B2 (en) 2017-01-05
WO2014093941A1 (en) 2014-06-19
EA201590862A1 (ru) 2016-05-31
CN104902905A (zh) 2015-09-09
BR112015013695A2 (pt) 2017-07-11
US9795619B2 (en) 2017-10-24
SG10201704467SA (en) 2017-06-29
CR20150313A (es) 2015-10-19
PH12015501156A1 (en) 2015-08-10
SG11201503807TA (en) 2015-06-29
US20180042944A1 (en) 2018-02-15
MX2015007563A (es) 2015-10-14
EP2931285A4 (en) 2016-06-01
ZA201503594B (en) 2018-11-28

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