HK1209372A1 - Low melting propionic acid derivative particles for use in oral dosage forms - Google Patents
Low melting propionic acid derivative particles for use in oral dosage formsInfo
- Publication number
- HK1209372A1 HK1209372A1 HK15110267.8A HK15110267A HK1209372A1 HK 1209372 A1 HK1209372 A1 HK 1209372A1 HK 15110267 A HK15110267 A HK 15110267A HK 1209372 A1 HK1209372 A1 HK 1209372A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- dosage forms
- propionic acid
- acid derivative
- low melting
- oral dosage
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/148—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Botany (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261702392P | 2012-09-18 | 2012-09-18 | |
US13/789,797 US20140256810A1 (en) | 2013-03-08 | 2013-03-08 | Low melting propionic acid derivative particles for use in oral dosage forms |
PCT/US2013/059918 WO2014047001A1 (en) | 2012-09-18 | 2013-09-16 | Low melting propionic acid derivative particles for use in oral dosage forms |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1209372A1 true HK1209372A1 (en) | 2016-04-01 |
Family
ID=49231643
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15110267.8A HK1209372A1 (en) | 2012-09-18 | 2015-10-19 | Low melting propionic acid derivative particles for use in oral dosage forms |
HK16100781.5A HK1212886A1 (zh) | 2012-09-18 | 2016-01-25 | 用於口服劑型的低熔點丙酸衍生物粒子 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16100781.5A HK1212886A1 (zh) | 2012-09-18 | 2016-01-25 | 用於口服劑型的低熔點丙酸衍生物粒子 |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP2897584A1 (pt) |
CN (1) | CN104640537A (pt) |
AU (1) | AU2013318356A1 (pt) |
BR (1) | BR112015005876A2 (pt) |
CA (1) | CA2884119A1 (pt) |
HK (2) | HK1209372A1 (pt) |
RU (1) | RU2015114540A (pt) |
WO (1) | WO2014047001A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2015110511A (ru) * | 2014-03-28 | 2016-10-20 | МакНЕЙЛ-ППС, ИНК. | Частицы производного пропионовой кислоты для прямого прессования |
CN109956860B (zh) * | 2019-03-08 | 2022-03-01 | 天津大学 | 一种布洛芬球形晶体的制备方法 |
CN116211807A (zh) * | 2019-11-25 | 2023-06-06 | 上海博志研新药物技术有限公司 | 布洛芬药物组合物、制备方法及应用 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1497044A (en) | 1974-03-07 | 1978-01-05 | Prodotti Antibiotici Spa | Salts of phenyl-alkanoic acids |
DE3440288A1 (de) | 1984-11-05 | 1986-05-07 | Gergely, Gerhard, Dr.-Ing., Wien | Pharmazeutische zubereitung mit einem gehalt an mindestens einer schleimhautreizenden substanz oder dergleichen, insbesondere profen, sowie verfahren zu ihrer herstellung |
US4923898A (en) | 1984-12-26 | 1990-05-08 | Analgesic Associates | Analgesic, anti-inflammatory and skeletal muscle relaxant compositions comprising non-steroidal anti-inflammatory drugs and musculoskeletal relaxants and methods of using same |
US4873231A (en) | 1986-04-08 | 1989-10-10 | Smith Walton J | Decreasing the toxicity of an ibuprofen salt |
CA2063141C (en) | 1989-08-04 | 1997-03-04 | Edward J. Roche | Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets |
IT1246383B (it) | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per il mascheramento del sapore di farmaci |
CA2061520C (en) | 1991-03-27 | 2003-04-22 | Lawrence J. Daher | Delivery system for enhanced onset and increased potency |
US5405617A (en) * | 1991-11-07 | 1995-04-11 | Mcneil-Ppc, Inc. | Aliphatic or fatty acid esters as a solventless carrier for pharmaceuticals |
WO1994005260A1 (en) | 1992-09-03 | 1994-03-17 | Affinity Biotech, Inc. | Taste-masking pharmaceutical compositions and methods for making the same |
IT1264855B1 (it) | 1993-06-21 | 1996-10-17 | Zambon Spa | Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici |
ZA945944B (en) | 1993-08-13 | 1996-02-08 | Eurand America Inc | Procedure for encapsulating nsaids |
TW442287B (en) | 1995-06-13 | 2001-06-23 | American Home Produits Corp | Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac) |
NZ333474A (en) | 1998-01-02 | 1999-06-29 | Mcneil Ppc Inc | A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat |
US6117452A (en) | 1998-08-12 | 2000-09-12 | Fuisz Technologies Ltd. | Fatty ester combinations |
FR2811912B1 (fr) | 2000-07-21 | 2003-02-07 | Gattefosse Ets Sa | Procede d'enrobage de particules solides par un agent thermofusible, et particules solides ainsi enrobees |
GB0113841D0 (en) | 2001-06-07 | 2001-08-01 | Boots Co Plc | Therapeutic agents |
JP2007516259A (ja) * | 2003-12-09 | 2007-06-21 | メッドクリスタルフォームズ、エルエルシー | 活性剤との混合相共結晶の調製方法 |
BRPI0419125A (pt) * | 2004-12-10 | 2007-12-11 | Council Scient Ind Res | composição farmacêutica e processo para a preparação de uma composição farmacêutica |
CN101528205A (zh) | 2006-10-25 | 2009-09-09 | 麦克内尔-Ppc股份有限公司 | 布洛芬组合物 |
-
2013
- 2013-09-16 AU AU2013318356A patent/AU2013318356A1/en not_active Abandoned
- 2013-09-16 EP EP13766453.8A patent/EP2897584A1/en not_active Withdrawn
- 2013-09-16 RU RU2015114540A patent/RU2015114540A/ru not_active Application Discontinuation
- 2013-09-16 WO PCT/US2013/059918 patent/WO2014047001A1/en active Application Filing
- 2013-09-16 CA CA2884119A patent/CA2884119A1/en not_active Abandoned
- 2013-09-16 BR BR112015005876A patent/BR112015005876A2/pt not_active IP Right Cessation
- 2013-09-16 CN CN201380048595.1A patent/CN104640537A/zh active Pending
-
2015
- 2015-10-19 HK HK15110267.8A patent/HK1209372A1/xx unknown
-
2016
- 2016-01-25 HK HK16100781.5A patent/HK1212886A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
RU2015114540A (ru) | 2016-11-10 |
BR112015005876A2 (pt) | 2017-07-04 |
EP2897584A1 (en) | 2015-07-29 |
AU2013318356A1 (en) | 2015-03-19 |
WO2014047001A1 (en) | 2014-03-27 |
HK1212886A1 (zh) | 2016-06-24 |
CN104640537A (zh) | 2015-05-20 |
CA2884119A1 (en) | 2014-03-27 |
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