HK1206995A1 - Methods for increasing cftr activity cftr - Google Patents

Methods for increasing cftr activity cftr

Info

Publication number
HK1206995A1
HK1206995A1 HK15107706.3A HK15107706A HK1206995A1 HK 1206995 A1 HK1206995 A1 HK 1206995A1 HK 15107706 A HK15107706 A HK 15107706A HK 1206995 A1 HK1206995 A1 HK 1206995A1
Authority
HK
Hong Kong
Prior art keywords
cftr
methods
increasing
activity
cftr activity
Prior art date
Application number
HK15107706.3A
Other languages
English (en)
Chinese (zh)
Inventor
Steven M Rowe
Mark Dransfield
Original Assignee
Uab Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab Research Foundation filed Critical Uab Research Foundation
Publication of HK1206995A1 publication Critical patent/HK1206995A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK15107706.3A 2012-04-06 2015-08-10 Methods for increasing cftr activity cftr HK1206995A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261621043P 2012-04-06 2012-04-06
PCT/US2013/032268 WO2013151758A2 (en) 2012-04-06 2013-03-15 Methods for increasing cftr activity

Publications (1)

Publication Number Publication Date
HK1206995A1 true HK1206995A1 (en) 2016-01-22

Family

ID=49301152

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15107706.3A HK1206995A1 (en) 2012-04-06 2015-08-10 Methods for increasing cftr activity cftr

Country Status (8)

Country Link
US (2) US20150065539A1 (ja)
EP (1) EP2833885A4 (ja)
JP (1) JP6525203B2 (ja)
CN (1) CN104619321A (ja)
AU (2) AU2013243857A1 (ja)
CA (1) CA2869257A1 (ja)
HK (1) HK1206995A1 (ja)
WO (1) WO2013151758A2 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5409010B2 (ja) 2005-12-28 2014-02-05 バーテックス ファーマシューティカルズ インコーポレイテッド Ｎ−［２，４−ビス（１，１−ジメチルエチル）−５−ヒドロキシフェニル］−１，４−ジヒドロ−４−オキソキノリン−３−カルボキサミドの固体形態
CA2963945C (en) 2014-10-07 2023-01-10 Vertex Pharmaceuticals Incorporated Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH690023A5 (de) * 1996-02-02 2000-03-31 Medichemie Ag Mittel zur Behandlung krankhafter Zellveränderungen der Nasenschleimhaut.
US20040266883A1 (en) * 1999-10-27 2004-12-30 Yale University Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
US7541466B2 (en) * 2003-12-23 2009-06-02 Genzyme Corporation Tetrahydroisoquinoline derivatives for treating protein trafficking diseases
CN102231990B (zh) 2008-08-13 2013-09-25 沃泰克斯药物股份有限公司 N-[2，4-双(1，1-二甲基乙基)-5-羟基苯基]-1，4-二氢-4-氧代喹啉-3-甲酰胺的药物组合物和其给药
US20100256184A1 (en) * 2008-08-13 2010-10-07 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
EP2475360A1 (en) * 2009-09-12 2012-07-18 Reckitt Benckiser LLC Use of guaifenesin for inhibiting mucin secretion
EP2547335A4 (en) * 2010-03-15 2014-04-16 Univ Virginia Commonwealth AEROSOLIC DAPSONE AS THERAPY AGAINST INFLAMMATION OF THE RESPIRATORY SYSTEM AND ANOMALY OF MUCOCILIARY TRANSPORT
EP3037415A1 (en) * 2010-03-19 2016-06-29 Vertex Pharmaceuticals Inc. Solid form of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
WO2012158885A1 (en) * 2011-05-18 2012-11-22 Concert Pharmaceuticals Inc. Deuterated derivatives of ivacaftor

Also Published As

Publication number Publication date
US20150065539A1 (en) 2015-03-05
AU2018200192B9 (en) 2019-07-25
AU2018200192B2 (en) 2019-06-06
CN104619321A (zh) 2015-05-13
JP2015521157A (ja) 2015-07-27
EP2833885A2 (en) 2015-02-11
US10300052B2 (en) 2019-05-28
CA2869257A1 (en) 2013-10-10
WO2013151758A2 (en) 2013-10-10
EP2833885A4 (en) 2015-12-16
AU2018200192A1 (en) 2018-02-01
JP6525203B2 (ja) 2019-06-05
US20170266177A1 (en) 2017-09-21
AU2013243857A1 (en) 2014-10-16

Similar Documents

Publication Publication Date Title
HK1250690A1 (zh) 方法
HK1208363A1 (en) New methods
GB201411223D0 (en) None
GB201211077D0 (en) Two-piece can
EP2833358A4 (en) DISK
GB2507760B (en) Methods
PL2838352T3 (pl) Wóz paszowy
EP2834351A4 (en) ACTIVITY OF METABOLITE MODIFIED BY AN ENZYME
GB2502122B (en) Amplifier
GB201208874D0 (en) Methods
ZA201409022B (en) 3-o-heteroaryl-ingenol
HU4381U (en) Arrangement for divided enery-production
GB201218867D0 (en) Acoustic pick-up assemblies
GB2500883B (en) Improved saw-horse
HK1206995A1 (en) Methods for increasing cftr activity cftr
GB201204280D0 (en) Methods
HK1212895A1 (zh) 用於免疫調節的沙奎那韋-
GB201208756D0 (en) Methods
GB201215582D0 (en) Biohaven
GB201213825D0 (en) Damper-device for bouncing-device
TWM433497U (en) Structure for jacklight
GB201220686D0 (en) Methods
AP2012000550S (en) E-horn methods
GB201216074D0 (en) Methods
GB201410091D0 (en) None