HK1206729A1 - [3-heteroaryl-2-trifluoromethyl-propyl]-piperidin-1-yle or - morpholin-4-yle compounds as trpa1 antagonists for the treatment of respiratory diseases trpa1 [3--2--]- -1---4- - Google Patents
[3-heteroaryl-2-trifluoromethyl-propyl]-piperidin-1-yle or - morpholin-4-yle compounds as trpa1 antagonists for the treatment of respiratory diseases trpa1 [3--2--]- -1---4-Info
- Publication number
- HK1206729A1 HK1206729A1 HK15107230.8A HK15107230A HK1206729A1 HK 1206729 A1 HK1206729 A1 HK 1206729A1 HK 15107230 A HK15107230 A HK 15107230A HK 1206729 A1 HK1206729 A1 HK 1206729A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- yle
- trpa1
- morpholin
- piperidin
- heteroaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
- C07D271/107—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with two aryl or substituted aryl radicals attached in positions 2 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261723932P | 2012-11-08 | 2012-11-08 | |
| PCT/EP2013/073129 WO2014072325A1 (fr) | 2012-11-08 | 2013-11-06 | Composés [3-hétéroaryl-2-trifluorométhyl-propyl]-pipéridin-1-yle ou -morpholin-4-yle en tant qu'antagonistes de trpa1 pour le traitement de maladies respiratoires |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1206729A1 true HK1206729A1 (en) | 2016-01-15 |
Family
ID=49584705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15107230.8A HK1206729A1 (en) | 2012-11-08 | 2015-07-28 | [3-heteroaryl-2-trifluoromethyl-propyl]-piperidin-1-yle or - morpholin-4-yle compounds as trpa1 antagonists for the treatment of respiratory diseases trpa1 [3--2--]- -1---4- |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9388172B2 (fr) |
| EP (1) | EP2917208A1 (fr) |
| JP (1) | JP2015536960A (fr) |
| KR (1) | KR20150079681A (fr) |
| CN (1) | CN104768947A (fr) |
| BR (1) | BR112015007507A2 (fr) |
| CA (1) | CA2884433A1 (fr) |
| HK (1) | HK1206729A1 (fr) |
| MX (1) | MX2015005426A (fr) |
| RU (1) | RU2015118740A (fr) |
| WO (1) | WO2014072325A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2805718B1 (fr) | 2012-01-17 | 2018-04-04 | EA Pharma Co., Ltd. | Dérivé d'amine hétérocyclique et produit pharmaceutique le contenant |
| IT202100015098A1 (it) | 2021-06-09 | 2022-12-09 | Flonext S R L | Composto antagonista del canale trpa1 per uso in patologie degenerative della retina |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05191578A (ja) | 1990-07-26 | 1993-07-30 | Ricoh Co Ltd | プリンタコントローラシステム |
| US5470189A (en) | 1994-04-19 | 1995-11-28 | Mi-Jack Products, Inc. | Side latch assembly for lifting trailers and containers |
| IL125658A0 (en) | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
| US7375125B2 (en) | 1999-08-04 | 2008-05-20 | Ore Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
| CA2413274A1 (fr) | 2000-06-21 | 2001-12-27 | George V. Delucca | N-ureidoalkyl-piperidines utiles comme modulateurs de l'activite du recepteur de chimiokine |
| US7709645B2 (en) | 2004-07-27 | 2010-05-04 | Sgx Pharmaceuticals, Inc. | Pyrrolo-pyridine kinase modulators |
| US20090105259A1 (en) | 2005-09-08 | 2009-04-23 | Jeong Jae U | Acyclic 1,4-Diamines and Uses Thereof |
| WO2011132017A1 (fr) | 2010-04-19 | 2011-10-27 | Glenmark Pharmaceuticals S.A. | Dérivés de pyrido[3,4-d]pyrimidinyl acétamide comme modulateurs de trpa1 |
-
2013
- 2013-11-06 CA CA2884433A patent/CA2884433A1/fr not_active Abandoned
- 2013-11-06 KR KR1020157011931A patent/KR20150079681A/ko not_active Application Discontinuation
- 2013-11-06 JP JP2015541112A patent/JP2015536960A/ja active Pending
- 2013-11-06 WO PCT/EP2013/073129 patent/WO2014072325A1/fr active Application Filing
- 2013-11-06 MX MX2015005426A patent/MX2015005426A/es unknown
- 2013-11-06 CN CN201380058111.1A patent/CN104768947A/zh active Pending
- 2013-11-06 RU RU2015118740A patent/RU2015118740A/ru not_active Application Discontinuation
- 2013-11-06 EP EP13791771.2A patent/EP2917208A1/fr not_active Withdrawn
- 2013-11-06 BR BR112015007507A patent/BR112015007507A2/pt not_active Application Discontinuation
-
2015
- 2015-05-08 US US14/707,524 patent/US9388172B2/en not_active Expired - Fee Related
- 2015-07-28 HK HK15107230.8A patent/HK1206729A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112015007507A2 (pt) | 2017-07-04 |
| CA2884433A1 (fr) | 2014-05-15 |
| EP2917208A1 (fr) | 2015-09-16 |
| MX2015005426A (es) | 2015-08-05 |
| RU2015118740A (ru) | 2016-12-27 |
| JP2015536960A (ja) | 2015-12-24 |
| KR20150079681A (ko) | 2015-07-08 |
| US20150239873A1 (en) | 2015-08-27 |
| WO2014072325A1 (fr) | 2014-05-15 |
| CN104768947A (zh) | 2015-07-08 |
| US9388172B2 (en) | 2016-07-12 |
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